Results 161 to 170 of about 30,178 (280)

A photoimmune synergizing RNA interference technology for highly effective antitumor treatment

open access: yesSmart Molecules, EarlyView.
We developed a red‐light‐activated small‐molecule photosensitizer FNBS, which enables simultaneous photodynamic immunotherapy and RNA interference. FNBS can induce pyroptosis, immunogenic cell death and RNA degradation, avoiding the carrier‐dependent delivery drawbacks of conventional RNAi therapy, converting cold tumors into hot tumors and ...
Xiang Xia   +6 more
wiley   +1 more source

Endovascular stem cell therapy reconfigures post-stroke ER dynamics via GRP78/Atlastin/CHOP axis. [PDF]

open access: yesMol Brain
Kumari A   +12 more
europepmc   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

open access: yesVIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin   +3 more
wiley   +1 more source

Rituximab-Conjugated DART Nanoformulation for CD20-Targeted Drug Delivery in Non-Hodgkin Lymphoma. [PDF]

open access: yesInt J Nanomedicine
Mahmud MM   +6 more
europepmc   +1 more source

Large‐Scale Applications of Plasma Technologies: Progresses and Challenges

open access: yesHigh Voltage, EarlyView.
ABSTRACT Plasma technologies convert electrical power into energetic electrons, ions, reactive species, radiation and heat, thereby breaking through the bottleneck of purely thermal or chemical routes and bringing impressive changes to our world. This roadmap reviews the progress and challenges of plasma technologies from a large‐scale and application ...
Pankaj Attri   +51 more
wiley   +1 more source

Integrating novel therapeutic strategies in myeloproliferative neoplasms: Driving disease‐directed progress

open access: yesBritish Journal of Haematology, EarlyView.
Summary Over the past decade, there has been a substantial increase in the diversity and number of therapeutic options for myeloproliferative neoplasms (MPNs). While many remain within the clinical trial arena, the clinician and patient community have seen more approvals reaching the clinic and a rethink on how best we should be approaching these ...
Trung Q. Ngo   +3 more
wiley   +1 more source

Survival outcomes and treatment patterns in myelofibrosis in the JAK inhibitor era

open access: yesBritish Journal of Haematology, EarlyView.
Summary Data on real‐world survival and treatment patterns in large, unselected myelofibrosis (MF) cohorts remain limited. We analysed 1649 patients with MF diagnosed from 2010 onwards and included in the Spanish Myelofibrosis Registry across 64 centres. Janus kinase (JAK) inhibitors were administered to approximately half of the patients.
Juan‐Carlos Hernández‐Boluda   +35 more
wiley   +1 more source

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