Results 161 to 170 of about 28,252 (277)

The Interaction Between <i>Echinococcus multilocularis</i> Calreticulin S-Domain and Human Complement C1q Inhibits C1q-Dependent Immune Functions. [PDF]

Pathogens
Xia M, Song Y, Dong X, Gu L, Wang Y, Sun W, Zhan B, Yan Y, Zhao L.   +8 more
europepmc   +1 more source

Nanomaterial‐Mediated Radiotherapy–Immunotherapy Combinations: Breaking Immunosuppression and Revolutionizing Cancer Treatment

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
Nanomaterials integrate radiotherapy and immunotherapy by enhancing radiosensitivity, remodeling the immunosuppressive tumor microenvironment, and promoting systemic antitumor immunity. This review summarizes the latest strategies of nanomaterial‐mediated combinations (RT, immunotherapy, IRT) and highlights future directions for overcoming clinical ...
Peijie Li, Xiangqin Wang, Sisi He, Hu Ma
wiley   +1 more source

Syntaxin 12 Sustains Endosomal‐Lysosomal Homeostasis and Survival in Glioblastoma Stem‐Like Cells

Traffic, Volume 27, Issue 3, September 2026.
Syntaxin12 maintains endolysosomal trafficking and lysosomal homeostasis in glioblastoma cells. Syntaxin12 depletion disrupts lysosomal organization, impairs endolysosomal progression and mTOR‐lysosome communication, and compromises adaptive pathways required for cell survival. ABSTRACT Glioblastoma cells display a striking vulnerability to disruptions
Clément Maghe, Agnieszka Barbach, Gwennan André‐Grégoire, Clotilde C. N. Renaud, Margaux Le Guyon, Rosalie Moreau, Nicolas Bidère, Julie Gavard   +7 more
wiley   +1 more source

MHC-I Upregulation and Increased Glucose Dependence Define Innate Antifungal Immune Responses to Cryptococcus neoformans. [PDF]

J Infect Dis
Nair AS, Wozniak KL.
europepmc   +1 more source

Calreticulin in plant cells [PDF]

, 1998
MARIANI, PAOLINA, NAVAZIO, LORELLA
core  

Goniothalamin as a Styryl‐Lactone Toxicophore in Cancer Models: Electrophile‐Driven DNA Damage, Reactive Oxygen Species–Endoplasmic Reticulum Stress Signaling and Detoxification‐Relevant Safety Considerations

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Nataša Joković, Strahinja Pešić, Marija Novaković, Anđela Dubroja Krstić, William N. Setzer, Javad Sharifi‐Rad, Daniela Calina   +6 more
wiley   +1 more source

EGFR-targeted photoimmunotherapy and its association with the immune microenvironment in locoregional recurrent head and neck squamous cell carcinoma. [PDF]

Front Immunol
Yoshizawa K, Tsujikawa T, Leelasawatsuk P, Bedeir MM, van der Aar Y, de Martines T, Shibata S, Ogi H, Okada R, Kimura A, Morimoto H, Saburi S, Mukudai S, Nagao H, Miyagawa-Hayashino A, Konishi E, Itoh K, Asakage T, Hirano S.   +18 more
europepmc   +1 more source

Inhibitory HLA‐C/KIR2DL2 Interactions and KIR Allelic Polymorphisms Are Associated With Susceptibility to Philadelphia Chromosome‐Negative Myeloproliferative Neoplasms

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Background Immune surveillance is increasingly recognized as a determinant of clonal selection in Philadelphia chromosome‐negative myeloproliferative neoplasms (MPN). While HLA‐restricted adaptive immune effects have been described, the contribution of inherited variation in natural killer (NK)‐cell regulatory pathways remains less well ...
Velizar Shivarov, Gergana Tsvetkova, Evgueniy Hadjiev, Milena Ivanova   +3 more
wiley   +1 more source

Cancer frenemy pathways: Inducing immunogenic cell death by exploiting apoptosis-interferon antagonism with oncolytic viruses. [PDF]

Mol Ther Oncol
Bozhdansky V, Bacharach E, Ehrlich M.
europepmc   +1 more source

Monitoring the Effect of Tributyltin Salicylate and Propionate, Retinoid X Receptor Ligands, on Heat Shock Protein Expression in MDA‐MB‐231 Cells by MALDI MS/MS

Journal of Mass Spectrometry, Volume 61, Issue 8, August 2026.
ABSTRACT Organotin (IV) compounds are known to induce apoptosis via the intrinsic mitochondrial pathway, which is a key mechanism of effective anticancer therapy. Their ability to selectively promote apoptotic cell death highlights their potential as chemotherapeutic agents. In this study, the in vitro effects of two triorganotin compounds, tributyltin
Dana Strouhalova, Dana Macejova, Julius Brtko, Janette Bobalova   +3 more
wiley   +1 more source