Results 171 to 180 of about 28,252 (277)
Frequency of Non-Type I/II <i>CALR</i> Mutations in Patients Undergoing Molecular Diagnostics for Myeloproliferative Neoplasms. [PDF]
Makarik T +7 more
europepmc +1 more source
The study constructed an integrated diagnosis‐treatment system by using engineered probiotic EcN expressing ARGs and Cur‐Lip‐FA. It enables US guided tumor targeting, real‐time in vivo drug monitoring, and US‐assisted curcumin induced immunogenic cell death, and activating the cGAS‐STING pathway to boost CD4+/CD8+ T cell anti‐tumor immunity.
Jie Long +14 more
wiley +1 more source
Volumetric Single-Molecule Tracking Inside Subcellular Structures. [PDF]
Daly S +8 more
europepmc +1 more source
Macrophage: Biological Functions, Diseases, and Therapeutic Targets
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun +4 more
wiley +1 more source
Cascade-activatable small-molecule theranostic nanomicelles for photodynamic-immunotherapy of immune-cold lung tumors. [PDF]
Yoon YC, Kim HJ, Choi Y.
europepmc +1 more source
A sonosensitizer‐functionalized polymetallic nanozyme PPBCH enables photoacoustic imaging‐guided sonodynamic cancer immunotherapy. Upon US irradiation activation, the nanozyme amplifies oxidative stress by generating O2, producing ROS, and depleting glutathione, thereby inducing ferroptotic stress and immunogenic cell death.
Caiying Li +10 more
wiley +1 more source
Mechanically Regulated Nanozymes for Remote Metabolic Reprogramming and Precise Cancer Therapy
Inspired by mechanoenzymes, a ferrocene‐based mechanically regulated nanozyme converts acoustic shear force into enhanced peroxidase‐like activity by decreasing electron density and alleviating steric hindrance at the Fe active sites, thereby rewiring redox homeostasis. Leveraging this remote regulatory mechanism, a multienzyme‐regulated nanoreactor is
Fangman Chen +13 more
wiley +2 more sources
Calreticulin in the nasal mucus promotes neutrophil migration and pathogen clearance. [PDF]
Ma Y +6 more
europepmc +1 more source

