Results 81 to 90 of about 266,269 (291)

A Survey of the Management and Development of Captive African Elephant (\u3cem\u3eLoxodonta africana\u3c/em\u3e) Calves: Birth to Three Months of Age [PDF]

open access: yes, 2010
We used four surveys to collect information about the birth, physical growth, and behavioral development of 12 African elephant calves born in captivity. The management of the birth process and neonatal care involved a variety of standard procedures. All
Dale, Robert H.I.   +2 more
core   +1 more source

From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function

open access: yesAdvanced Healthcare Materials, EarlyView.
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini   +2 more
wiley   +1 more source

Ion‑Mediated Structural Engineering of Hydrogel Interfaces for Tunable Mechanical and Analyte Diffusion Properties in Electrochemical Biosensors

open access: yesAdvanced Materials, EarlyView.
An ion‐mediated structural engineering strategy enables versatile modulation of PVA–Alginate hydrogel microstructure. We systematically examine how different ion combinations affect hydrogel mechanical properties and analyte diffusivity. Applying this novel strategy to hydrogel as the outer membrane in an electrochemical glucose biosensor allows ...
Dongwook Lee   +14 more
wiley   +1 more source

Impact of different handling styles (good vs. adverse) on growth performance, behavior, and cortisol concentrations in beef cattle [PDF]

open access: yes, 2012
Our objective was to determine effects of aggressive handling on growth performance, behavior, and cortisol concentrations in beef calves. Crossbred calves (313 ± 4.7 kg; n = 54; 24 steers, 30 heifers) from a single herd were stratified by gender, body ...
Bauer, Joan   +5 more
core   +2 more sources

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

open access: yesAdvanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode   +16 more
wiley   +1 more source

Characterization of the preweaned Holstein calf fecal microbiota prior to, during, and following resolution of uncomplicated gastrointestinal disease

open access: yesFrontiers in Microbiology
Little is known about shifts in the fecal microbiome of dairy calves preceding and following the incidence of gastrointestinal disease. The objective of this cohort study was to describe the fecal microbiome of preweaned dairy calves before, during, and ...
Rachel A. Claus-Walker   +7 more
doaj   +1 more source

Calf mortality of semi-domesticated reindeer (Rangifer tarandus tarandus) in the Finnish reindeer-herding area

open access: yesRangifer, 2013
During 1999-2008 calf mortality was studied in six reindeer-herding cooperatives in Northern Finland, where 3942 semi-domesticated reindeer (Rangifer tarandus tarandus) calves were equipped with radio mortality collars.
Mauri Nieminen   +2 more
doaj   +1 more source

Development of a novel clinical scoring system for on-farm diagnosis of bovine respiratory disease in pre-weaned dairy calves. [PDF]

open access: yes, 2014
Several clinical scoring systems for diagnosis of bovine respiratory disease (BRD) in calves have been proposed. However, such systems were based on subjective judgment, rather than statistical methods, to weight scores.
Aly, Sharif S   +4 more
core   +2 more sources

Oxygen‐Inhibition Driven Compartmentalization of Dextran Microgels: Toward Fusible Colloidal Biomaterial Inks for 3D Printing

open access: yesAdvanced Materials, EarlyView.
Harnessing oxygen inhibition as a materials design principle enables the universal fabrication of core–shell microgels with tunable radial crosslinking gradients. This conceptually simple yet highly versatile strategy generates fusible colloidal bioinks that combine structural hierarchy with adaptive porosity.
Selin Bulut   +8 more
wiley   +1 more source

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

open access: yesAdvanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade   +19 more
wiley   +1 more source

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