Results 11 to 20 of about 3,139,231 (313)
Safety and Effectiveness of Chemotherapy in Elderly Biliary Tract Cancer Patients
Current Oncology, 2023 The safety and effectiveness of chemotherapy in elderly patients with biliary tract cancer (BTC) remain unclear. Therefore, we retrospectively reviewed patients who underwent chemotherapy for locally advanced, metastatic, or recurrent BTC at our ...
Takeshi Okamoto +12 more
doaj +1 more source
LAG-3 in Cancer Immunotherapy [PDF]
, 2010 LAG-3 (CD223) is a cell surface molecule expressed on activated T cells (Huard et al. Immunogenetics 39:213-217, 1994), NK cells (Triebel et al. J Exp Med 171:1393-1405, 1990), B cells (Kisielow et al. Eur J Immunol 35:2081-2088, 2005), and plasmacytoid dendritic cells (Workman et al.
Monica V, Goldberg, Charles G, Drake
openaire +2 more sources
Targeting Tumor Mitochondrial Metabolism Overcomes Resistance to Antiangiogenics
Cell Reports, 2016 Epithelial malignancies are effectively treated by antiangiogenics; however, acquired resistance is a major problem in cancer therapeutics. Epithelial tumors commonly have mutations in the MAPK/Pi3K-AKT pathways, which leads to high-rate aerobic ...
Paloma Navarro +11 more
doaj +1 more source
Two cases of spindle cell variant diffuse large B-cell lymphoma of the uterine cervix
Gynecologic Oncology Reports, 2020 Lymphoma with prominent spindle cell features is a morphological variant of diffuse large B-cell lymphoma (DLBCL) and is categorized as a rare variant by the WHO classification.
Hiroko Murata +6 more
doaj +1 more source
Gynecologic Oncology Reports, 2021 In 2003, Höckel described the laterally extended endopelvic resection (LEER), which may be an effective surgical technique for patients with laterally recurrent cervical cancer (Höckel, 2003).
Hiroyuki Kanao +5 more
doaj +1 more source
Respiratory Medicine Case Reports, 2020 A 69-year-old man had experienced right chest pain for several months. Chest computed tomography (CT) showed a right upper lobe lung tumor and swelling of multiple mediastinal and right hilar lymph node.
Takako Inoue +9 more
doaj +1 more source
Diagnostics, 2018 Pancreatic cancer (PC) is the fourth leading cause of cancer-related death with a 5-year survival rate less than 10%. In the absence of effective screening methods, such as blood markers, most clinical diagnoses of PC are made at an advanced stage ...
Reiko Ashida +8 more
doaj +1 more source
Early differential responses elicited by BRAFV600E in adult mouse models
Cell Death and Disease, 2022 The BRAF gene is frequently mutated in cancer. The most common genetic mutation is a single nucleotide transition which gives rise to a constitutively active BRAF kinase (BRAFV600E) which in turn sustains continuous cell proliferation.
Giuseppe Bosso +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.
Stefan Rutkowski +59 more
wiley +1 more source
Update Breast Cancer 2020 Part 3 – Early Breast Cancer [PDF]
Geburtshilfe und Frauenheilkunde, 2020 AbstractThe treatment of patients with early breast cancer has always been characterised by escalation by new therapies and de-escalation through identification of better treatment regimens or introduction of better tools to estimate prognosis. Efforts in some of these areas in the last few years have led to solid data. The results of the large studies
Huober, Jens +18 more
openaire +2 more sources