Results 31 to 40 of about 3,561,997 (213)

Two cases of spindle cell variant diffuse large B-cell lymphoma of the uterine cervix

Gynecologic Oncology Reports, 2020
Lymphoma with prominent spindle cell features is a morphological variant of diffuse large B-cell lymphoma (DLBCL) and is categorized as a rare variant by the WHO classification.
Hiroko Murata, Harumi Nakamura, Yukinobu Ohta, Masanori Kitamura, Shinichi Nakastuka, Jun Ishikawa, Shoji Kamiura   +6 more
doaj   +1 more source

Safety and Effectiveness of Chemotherapy in Elderly Biliary Tract Cancer Patients

Current Oncology, 2023
The safety and effectiveness of chemotherapy in elderly patients with biliary tract cancer (BTC) remain unclear. Therefore, we retrospectively reviewed patients who underwent chemotherapy for locally advanced, metastatic, or recurrent BTC at our ...
Takeshi Okamoto, Tsuyoshi Takeda, Takashi Sasaki, Tsuyoshi Hamada, Takafumi Mie, Takahiro Ishitsuka, Manabu Yamada, Hiroki Nakagawa, Tatsuki Hirai, Takaaki Furukawa, Akiyoshi Kasuga, Masato Ozaka, Naoki Sasahira   +12 more
doaj   +1 more source

The Genetic Landscape and Clonal Evolution of Breast Cancer Resistance to Palbociclib plus Fulvestrant in the PALOMA-3 Trial [PDF]

, 2018
CDK4/6 inhibition with endocrine therapy is now a standard of care for advanced estrogen receptor-positive breast cancer. Mechanisms of CDK4/6 inhibitor resistance have been described preclinically, with limited evidence from clinical samples.
Liu, Y, Sibylle Loibl, Loi, S, Rosalind J. Cutts, Huang Bartlett, C, André, F, Fabrice André, Cynthia Huang Bartlett, Cutts, RJ, Nicholas C. Turner, Cristofanilli, M, Sarah Hrebien, Garcia-Murillas, I, Hrebien, S, Kerry Fenwick, Loibl, S, Fenwick, K, Yuan Liu, Huang, X, Sherene Loi, Turner, NC, Ben O'Leary, Isaac Garcia-Murillas, Massimo Cristofanilli, Xin Huang, O'Leary, B   +25 more
core   +1 more source

Targeting Tumor Mitochondrial Metabolism Overcomes Resistance to Antiangiogenics

Cell Reports, 2016
Epithelial malignancies are effectively treated by antiangiogenics; however, acquired resistance is a major problem in cancer therapeutics. Epithelial tumors commonly have mutations in the MAPK/Pi3K-AKT pathways, which leads to high-rate aerobic ...
Paloma Navarro, Maria J. Bueno, Ivana Zagorac, Tamara Mondejar, Jesus Sanchez, Silvana Mourón, Javier Muñoz, Gonzalo Gómez-López, Veronica Jimenez-Renard, Francisca Mulero, Navdeep S. Chandel, Miguel Quintela-Fandino   +11 more
doaj   +1 more source

Differences between laparoscopic super-radical hysterectomy and laterally extended endopelvic resection

Gynecologic Oncology Reports, 2021
In 2003, Höckel described the laterally extended endopelvic resection (LEER), which may be an effective surgical technique for patients with laterally recurrent cervical cancer (Höckel, 2003).
Hiroyuki Kanao, Tomoko Kurita, Yuji Tanaka, Atsushi Fusegi, Yoichi Aoki, Hidetaka Nomura   +5 more
doaj   +1 more source

A Phase II Study of Talazoparib after Platinum or Cytotoxic Nonplatinum Regimens in Patients with Advanced Breast Cancer and Germline BRCA1/2 Mutations (ABRAZO). [PDF]

, 2019
PURPOSE: To assess talazoparib activity in germline BRCA1/2 mutation carriers with advanced breast cancer. PATIENTS AND METHODS: ABRAZO (NCT02034916) was a two-cohort, two-stage, phase II study of talazoparib (1 mg/day) in germline BRCA mutation carriers
Grischke, E-M, Rugo, HS, Mailliez, A, Fasching, PA, Hannah, AL, Robson, ME, Chappey, C, Mina, LA, Hurvitz, SA, Turner, NC, Wardley, AM, Telli, ML, ABRAZO Study Group,, Ettl, J, Balmaña, J   +14 more
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Androgens are differentially associated with ovarian cancer subtypes in the Ovarian Cancer Cohort Consortium [PDF]

, 2017
Invasive epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy. The etiology of EOC remains elusive; however, experimental and epidemiologic data suggest a role for hormone-related exposures in ovarian carcinogenesis and risk factor ...
Antonia Trichopoulou, Tjonneland, Anne, Onland-Moret, NC, Eric J. Duell, Fortner, RT, Merritt, Melissa A., Ose, J, Masala, G, Onland-Moret, N Charlotte, Rinaldi, S, Poole, EM, Buring, JE, Tworoger, Shelley S., Schock, H, Dossus, L, Weiderpass, Elisabete, Travis, Ruth C., Tjønneland, A, Idahl, A, Renée T. Fortner, Helzlsouer, Kathy J., Duell, Eric J, Matti Lehtinen, Ruth C. Travis, Zeleniuch-Jacquotte, Anne, Helzlsouer, Kathy J, Schock, Helena, Trichopoulou, Antonia, Lehtinen, M, Annika Idahl, Arslan, AA, Wentzensen, N, Lee, I-Min, Merritt, Melissa A, Britton Trabert, Tworoger, Shelley S, Wentzensen, Nicolas, Elizabeth M. Poole, Rudolf Kaaks, Duell, Eric J., Rinaldi, Sabina, Helena Schock, Julie E. Buring, Masala, Giovanna, Kaaks, Rudolf, Weiderpass, E, Shelley S. Tworoger, Zeleniuch-Jacquotte, A, Giovanna Masala, Sabina Rinaldi, Kala Visvanathan, Helzlsouer, KJ, Lee, IM, Helzlsouer, Kathy, Anne Zeleniuch-Jacquotte, Duell, EJ, Poole, Elizabeth M, Nicolas Wentzensen, Arslan, Alan A, Idahl, Annika, I-Min Lee, Trabert, B, N. Charlotte Onland-Moret, Buring, Julie E, Laure Dossus, Buring, Julie E., Trabert, Britton, Fortner, Renée T, Visvanathan, K, Merritt, MA, Idahl, Annika,, Poole, Elizabeth M., Tjønneland, Anne, Elisabete Weiderpass, Travis, Ruth C, Kathy Helzlsouer, Melissa A. Merritt, Trichopoulou, A, Dossus, Laure, Lee, I. Min, Jennifer Ose, Anne Tjønneland, Kaaks, R, Arslan, Alan A., Travis, RC, Lehtinen, Matti, Visvanathan, Kala, Onland-Moret, N. Charlotte, Fortner, Renée T., Alan A. Arslan, Tworoger, SS, Ose, Jennifer   +91 more
core   +1 more source

Preventative therapies for healthy women at high risk of breast cancer [PDF]

, 2014
Ivana Sestak Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London, UKAbstract: Tamoxifen has been shown to reduce the risk of developing estrogen receptor (ER)-positive ...
Sestak I, Sestak, I
core   +1 more source

The Role of Transabdominal Ultrasound in the Diagnosis of Early Stage Pancreatic Cancer: Review and Single-Center Experience

Diagnostics, 2018
Pancreatic cancer (PC) is the fourth leading cause of cancer-related death with a 5-year survival rate less than 10%. In the absence of effective screening methods, such as blood markers, most clinical diagnoses of PC are made at an advanced stage ...
Reiko Ashida, Sachiko Tanaka, Hiromi Yamanaka, Suetsumi Okagaki, Keiko Nakao, Junko Fukuda, Miho Nakao, Tatsuya Ioka, Kazuhiro Katayama   +8 more
doaj   +1 more source

Infectious pericarditis caused by Gemella sanguinis induced by Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA): A case report

Respiratory Medicine Case Reports, 2020
A 69-year-old man had experienced right chest pain for several months. Chest computed tomography (CT) showed a right upper lobe lung tumor and swelling of multiple mediastinal and right hilar lymph node.
Takako Inoue, Tatsuya Nishikawa, Kei Kunimasa, Motohiro Tamiya, Hanako Kuhara, Kazumi Nishino, Mamoru Fujiwara, Masashi Fujita, Fumio Imamura, Toru Kumagai   +9 more
doaj   +1 more source