Results 51 to 60 of about 3,561,997 (213)

Desmocollin-3 and Bladder Cancer

Diseases
Background: Desmocollin3, a transmembrane protein, is expressed in the basal/suprabasal layer of normal stratified epithelium. DSC3 gene expression is described in muscle-invasive bladder cancer (MIBC). DSC3-protein-expressing recurrent non-muscle-invasive bladder cancer (NMIBC) had a durable response to CADI-03, a DSC3-specific active immunotherapy ...
Chandreshwar P. Shukla, Nayan K. Jain, Michael A. O’Donnell, Kapil V. Vachhani, Rashmi Patel, Janki Patel, Rajiv Modi, Arpit Dheeraj, Jee Min Lee, Annah Rolig, Sanjay V. Malhotra, Bakulesh Khamar   +11 more
openaire   +3 more sources

Prognostic impact of coexisting cardiovascular disease in patients with cancer: A multicenter retrospective cohort study

Heliyon
Background: The incidence of malignancy and cardiovascular disease (CVD) is increasing worldwide. However, it is not entirely clear how the coexistence of CVD at the time of cancer diagnosis affects the overall survival of patients with cancer.
Yoshihiro Kuwabara, Toshitaka Morishima, Haruka Kudo, Chaochen Ma, Mizuki Shimadzu Kato, Shihoko Koyama, Kayo Nakata, Takahiro Tabuchi, Isao Miyashiro   +8 more
doaj   +1 more source

Indole-3-Carbinol and Prostate Cancer [PDF]

The Journal of Nutrition, 2004
Epidemiological and dietary studies have revealed an association between high dietary intake of cruciferous vegetables and decreased prostate cancer risk. Our studies have shown that indole-3-carbinol (I3C), a common phytochemical in cruciferous vegetables, and its in vivo dimeric product 3,3'-diindolylmethane (DIM) upregulate the expression of phase I
Fazlul H, Sarkar, Yiwei, Li
openaire   +2 more sources

Clinical usefulness of cancer markers in primary breast cancer [PDF]

, 2011
The aim of this study was to investigate the diagnostic power of CA 549, MSA and CA 15-3 in identifying breast cancer. The study included 232 patients of which 56 were healthy, 43 had benign breast cancer and 191 with other growths.
Verring, A., Ziolkowski, Piotr, Oremek, Gerhard, Clouth, Aline   +3 more
core   +1 more source

Cancer Research UK COVID Cancer Awareness Measures: Wave 1 and Wave 2, 2020-2021: Special Licence Access [PDF]

, 2023
copyright UK Data Service and data collection copyright owner.The Cancer Awareness Measure (CAM) was developed in 2007-8 to address the absence of a validated measure of general public awareness of cancer (Stubbings, S., Robb, K., Waller ...
Cancer Research UK
core   +1 more source

Regional pancreatoduodenectomy versus standard pancreatoduodenectomy with portal vein resection for pancreatic ductal adenocarcinoma with portal vein invasion

BJS Open, 2020
Background Pancreatoduodenectomy (PD) with portal vein resection (PVR) is a standard operation for pancreatic ductal adenocarcinoma (PDAC) with portal vein (PV) invasion, but positive margin rates remain high.
A. Oba, H. Ito, Y. Ono, T. Sato, Y. Mise, Y. Inoue, Y. Takahashi, A. Saiura   +7 more
doaj   +1 more source

Function of Human Tumor-Infiltrating Lymphocytes in Early-Stage Non-Small Cell Lung Cancer. [PDF]

Cancer progression is marked by dysfunctional tumor-infiltrating lymphocytes (TIL) with high inhibitory receptor (IR) expression. Because IR blockade has led to clinical responses in some patients with non-small cell lung cancer (NSCLC), we investigated ...
O'Brien, SM, Martinez, MC, Moon, EK, Kim, S, Litzky, LA, Hwang, W-T, Thompson, JC, Eruslanov, EB, Albelda, SM, Standalick, JE, Rao, AS, Klampatsa, A, Cantu, E, Singhal, S   +13 more
core   +2 more sources

EGFR T790M mutation after chemotherapy for small cell lung cancer transformation of EGFR-positive non-small cell lung cancer

Respiratory Medicine Case Reports, 2018
In non-small cell lung cancer (NSCLC) with an epidermal growth factor receptor (EGFR) mutation, 50%–65% of cases acquire resistance after treatment with EGFR-tyrosine kinase inhibitors (EGFR-TKIs) because of an EGFR T790M point mutation and 3%–14% of ...
Tomoaki Sonoda, Shingo Nishikawa, Rie Sakakibara, Masafumi Saiki, Ryo Ariyasu, Junji Koyama, Satoru Kitazono, Noriko Yanagitani, Atsushi Horiike, Fumiyoshi Ohyanagi, Hironori Ninomiya, Yuichi Ishikawa, Makoto Nishio   +12 more
doaj   +1 more source

The ErbB signalling pathway: protein expression and prognostic value in epithelial ovarian cancer [PDF]

, 2008
Ovarian cancer is the most frequent cause of death from gynaecological cancer in the Western world. Current prognostic factors do not allow reliable prediction of response to chemotherapy and survival for individual ovarian cancer patients.
de Bock, G. H., A P G Crijns, Hollema, H., P de Graeff, de Bock, G.H.; id_orcid, de Vries, E.G.; id_orcid, Crijns, A.P.G., G H de Bock, de Bock, G.H., A G J van der Zee, Bartlett, J.M., H G Klip, S de Jong, de Graeff, P., J M Bartlett, van der Zee, A. G. J., Crijns, A. P. G., ten Hoor, K.A., de Vries, E.G.E., van der Zee, A.G.J., Wisman, G.B., ten Hoor, K. A., de Vries, E. G. E., Bartlett, J. M., H Hollema, K A ten Hoor, Klip, H. G., G B A Wisman, de Jong, S., Wisman, G. B. A., Klip, H.G., van der Zee, A.G., de Jong, S.; id_orcid, Crijns, A.P., K Oien, Oien, K., Wisman, G.B.A., de Vries, E.G., E G E de Vries   +38 more
core   +1 more source

GSK-3 and mitochondria in cancer cells [PDF]

Frontiers in Oncology, 2013
GSK-3 is a multifunctional kinase that is located in the cytosol, nucleus, and mitochondria of all cell types, and it is involved in the pathogenesis of a variety of diseases. In cancer, GSK-3 modulates the response of the cell death machinery to stress stimuli, including chemotherapeutics.
CHIARA, FEDERICA, RASOLA, ANDREA
openaire   +4 more sources