Results 61 to 70 of about 23,963,911 (309)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Cancer trends: no. 3. Recent trends in prostate cancer
, 2010 Prostate cancer incidence increased by 4% annually between 1994 and 1998, but then increased sharply between 1998 and 2004 (Figure 1), by 11% for case numbers and 9% for age-standardised rate.
National Cancer Registry Ireland (NCRI)
core
Cancer Trends: Soft Tissue Sarcomas [PDF]
, 2014 Sarcomas are a group of uncommon cancers that originate from mesenchymal cells as opposed to more well-known cancers that develop from epithelial tissue.
National Cancer Registry Ireland (NCRI)
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Cancer in Ireland 1994-2021: Annual statistical report of the National Cancer Registry [PDF]
, 2023 The latest Annual Statistical Report from the National Cancer Registry (NCRI) focuses on the impact of age and stage at diagnosis on cancer outcomes. The report titled: Cancer in Ireland 1994 – 2021 is an analysis of nationally collated data revealing ...
National Cancer Registry Ireland (NCRI)
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The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Galectin 3 for the diagnosis of bladder cancer
Arab Journal of Urology, 2014 To evaluate serum levels of galectin-3 (G-3) in patients with bladder cancer and a control group, as a potential diagnostic and prognostic serum tumour marker.Between November 2012 and January 2013, 55 patients (median age 58 years) were enrolled into three groups, i.e., a control, those with transitional cell carcinoma (TCC) or those with squamous ...
El Gendy, Hoda +7 more
openaire +2 more sources
Cancer Trends: Cancer of the liver and biliary tract
, 2010 Liver cancer consists of two main types—hepatocellular carcinoma (HCC) which accounts for about 60% of cases, and intrahepatic bile duct cholangiocarcinoma (ICC), which accounts for about 20%. The liver is one of the less common cancer sites, about 0.
National Cancer Registry Ireland (NCRI)
core
Journal of Bone OncologyBackground: Denosumab is widely used to prevent skeletal-related events (SREs) in patients with bone metastases. However, rebound bone resorption after discontinuation is recognized.
Nokitaka Setsu +5 more
doaj +1 more source