Results 81 to 90 of about 23,963,911 (309)

HPV-associated cancers: cancer trends report [PDF]

open access: yes
Human papilloma virus (HPV) is a group of viruses known to infect the genital area, as well as the mouth and the throat. There are 13 HPV subtypes which are considered high-risk, as these are more likely to cause cell changes that over time can develop ...
National Cancer Registry Ireland (NCRI)
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Cancer Trends: Mesothelioma

open access: yes, 2012
Mesothelioma is a rare cancer of the thin lining that mainly covers the lungs and abdominal cavity. An average of 24 cases of mesothelioma was diagnosed per year in Ireland between 1994 and 2010 (Table 1), representing less than 0.2% of all invasive ...
National Cancer Registry Ireland (NCRI)
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Cancer Trends: Cancer of the pancreas

open access: yes, 2012
Cancer of the pancreas accounts for approximately 2.5% of all invasive cancers and is the 9th most commonly diagnosed cancer in Ireland.1 Almost 400 cases of pancreatic cancer were diagnosed annually between 1994 and 2010 (Table 1).
National Cancer Registry Ireland (NCRI)
core  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Cancer Trends: Cancers of the testis

open access: yes, 2012
An average of 132 cases of testicular cancer was diagnosed per year in Ireland between 1994 and 2010 (Table 1). Almost all cases were microscopically verified (98%) and were germ-cell tumours—57% of which were seminomatous and 40% non-seminomatous ...
National Cancer Registry Ireland (NCRI)
core  

Diagnosing cancer in an emergency: Patterns of emergency presentation of cancer in Ireland 2002–2015 [PDF]

open access: yes, 2018
Emergency presentation with cancer can result from lack of awareness of symptoms in patients and is generally associated with more advanced stage, limited treatment options and poorer survival outcomes.
National Cancer Registry Ireland (NCRI)   +1 more
core  

PB1788: A SCREENING OF DONATED CHEMICAL PROBES TO IDENTIFY NOVEL THERAPEUTIC OPTIONS FOR ACUTE MYELOID LEUKEMIA (AML) IN CHILDHOOD

open access: yesHemaSphere, 2023
Stephanie Laszig   +3 more
doaj   +1 more source

Impact of body surface area on efficacy and safety in patients with EGFR-mutant non-small cell lung cancer treated with osimertinib as a first-line treatment

open access: yesCancer Treatment and Research Communications
Background: The most recommended treatment for stage IV EGFR-positive lung cancer is osimertinib monotherapy. The dosage of osimertinib is fixed at 80 mg/day regardless of body surface area (BSA), however some patients withdraw or reduce the dosage due ...
Saki Tanaka   +15 more
doaj   +1 more source

Home - About - Disclaimer - Privacy