Results 101 to 110 of about 3,561,997 (213)

CYP3A variation, premenopausal estrone levels, and breast cancer risk. [PDF]

, 2012
BACKGROUND: Epidemiological studies have provided strong evidence for a role of endogenous sex steroids in the etiology of breast cancer. Our aim was to identify common variants in genes involved in sex steroid synthesis or metabolism that are associated
Gibson, Lorna J, Jones, M, Tomlinson, IP, Ross, G, Folkerd, Elizabeth, Hillier, Stephen G, Schoemaker, M, Sawyer, Elinor, Folkerd, E, Kerin, M, Ross, Gillian, Peto, Julian, Swerdlow, A, Johnson, Nichola, Tomlinson, Ian P., Coupland, Ben, Fletcher, Olivia, Haynes, Ben, Kerin, Michael J, Williamson, Jill, Schoemaker, Minouk, Coupland, B, Simpson, Gemma, Palles, Claire, Ashworth, A, Dowsett, M, Houlston, RS, Johnson, N, Swerdlow, Anthony, Jones, Michael, Chilcott-Burns, S, Dos-Santos-Silva, Isabel, Williamson, J, Broderick, P, Zvelebil, M, Dowsett, Mitch, Walker, Kate, Fletcher, O, Houlston, Richard S, Dos Santos Silva, I, Kerin, Michael, Tomczyk, K, Walker, K, Palles, C, Zvelebil, Marketa, Gibson, Lorna J., Ashworth, Alan, Tomlinson, Ian P, Tomczyk, Katarzyna, Simpson, G, Orr, Nick; id_orcid, Orr, Nick, Orr, N, Swerdlow, Anthony J, Houlston, Richard S., Peto, J, Dos Santos Silva, Isabel, Hillier, Stephen G., Haynes, B, Hillier, SG, Sawyer, E, Broderick, Peter, Chilcott-Burns, Sarah, Gibson, LJ, Walker-Springett, Kate   +64 more
core   +1 more source

P45. SURGICAL MANAGEMENT AND LONG-TERM OUTCOMES OF BIA-ALCL: A MULTI-DISCIPLINARY APPROACH

Plastic and Reconstructive Surgery, Global Open, 2022
Joshua Vorstenbosch, MD, PhD, Paola Ghione, MD, Steven M. Horwitz, MD, Peter G. Cordeiro, MD, Jonas A. Nelson, MD, MPH, Colleen M. McCarthy, MD   +5 more
doaj   +1 more source

Impact of body surface area on efficacy and safety in patients with EGFR-mutant non-small cell lung cancer treated with osimertinib as a first-line treatment

Cancer Treatment and Research Communications
Background: The most recommended treatment for stage IV EGFR-positive lung cancer is osimertinib monotherapy. The dosage of osimertinib is fixed at 80 mg/day regardless of body surface area (BSA), however some patients withdraw or reduce the dosage due ...
Saki Tanaka, Motohiro Tamiya, Satoshi Nishiuma, Sayaka Nakamura, Keisuke Nozaki, Naoko Watanabe, Chisae Itoh, Yukio Kadokawa, Kenji Takeda, Kozo Takahashi, Akito Miyazaki, Takahisa Kawamura, Kei Kunimasa, Takako Inoue, Kazumi Nishino, Mari Takagi   +15 more
doaj   +1 more source

A Unique Anti-Cancer 3-Styrylchromone Suppresses Inflammatory Response via HMGB1-RAGE Signaling. [PDF]

Medicines (Basel), 2021
Abe H, Okazawa M, Oyama T, Yamazaki H, Yoshimori A, Kamiya T, Tsukimoto M, Takao K, Sugita Y, Sakagami H, Abe T, Tanuma SI.   +11 more
europepmc   +1 more source

Prospero homeobox 1 promotes epithelial-mesenchymal transition in colon cancer cells by inhibiting E-cadherin via miR-9 [PDF]

, 2012
[[abstract]]PURPOSE: Prospero homeobox 1 (PROX1) has been shown to function as a tumor suppressor in various types of cancer. However, it promotes colon cancer progression.
Lu, MH;Huang, CC;Pan, MR;Chen, HH;Hung, WC
core   +1 more source

Effects of intrafractional diaphragm motion on dose perturbation in stereotactic body radiation therapy for lower thoracic vertebrae

Physics and Imaging in Radiation Oncology
Background and Purpose: This study aimed to evaluate the impact of intrafractional diaphragm motion (IFDM) on dose accuracy in stereotactic body radiation therapy (SBRT) for lower thoracic vertebrae.
Fumiyasu Matsubayashi, Kosuke Matsuura, Yasushi Ito, Yasuo Yoshioka   +3 more
doaj   +1 more source

Outcomes and toxicities after proton partial breast radiotherapy for early stage, hormone receptor positive breast cancer: 3-Year results of a phase II multi-center trial. [PDF]

Clin Transl Radiat Oncol, 2022
Choi JI, Prabhu K, Hartsell WF, DeWees T, Sinesi C, Vargas C, Benda RK, Cahlon O, Chang AL.   +8 more
europepmc   +1 more source

B7 homolog 3 in pancreatic cancer

World Journal of Gastroenterology
Despite advances in cancer treatment, pancreatic cancer (PC) remains a disease with high mortality rates and poor survival outcomes. The B7 homolog 3 (B7-H3) checkpoint molecule is overexpressed among many malignant tumors, including PC, with low or absent expression in healthy tissues. By modulating various immunological and nonimmunological molecular
Perovic, Dijana, Dusanovic Pjevic, Marija, Perovic, Vladimir, Grk, Milka, Rasic, Milica, Milickovic, Maja, Mijovic, Tanja, Rasic, Petar   +7 more
openaire   +2 more sources

P405: INHIBITION OF CKS1-DEPENDENT PROTEOSTASIS REVEALS VULNERABILITIES IN LEUKAEMIC STEM CELLS WITH CONCOMITANT PROTECTION OF HEALTHY HAEMATOPOIETIC STEM CELLS

HemaSphere, 2022
W. Grey, A. Rio-Machin, P. Casado-Izquierdo, E. Gronroos, S. Ali, J. Miettinen, F. Bewicke-Copley, A. Parsons, C. Heckman, C. Swanton, P. Cutillas, J. Gribben, J. Fitzgibbon, D. Bonnet   +13 more
doaj   +1 more source

Durvalumab, with or without tremelimumab, plus platinum-etoposide in first-line treatment of extensive-stage small-cell lung cancer: 3-year overall survival update from CASPIAN. [PDF]

ESMO Open, 2022
Paz-Ares L, Chen Y, Reinmuth N, Hotta K, Trukhin D, Statsenko G, Hochmair MJ, Özgüroğlu M, Ji JH, Garassino MC, Voitko O, Poltoratskiy A, Musso E, Havel L, Bondarenko I, Losonczy G, Conev N, Mann H, Dalvi TB, Jiang H, Goldman JW.   +20 more
europepmc   +1 more source