Results 21 to 30 of about 3,550,326 (312)

Androgens are differentially associated with ovarian cancer subtypes in the Ovarian Cancer Cohort Consortium [PDF]

open access: yes, 2017
Invasive epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy. The etiology of EOC remains elusive; however, experimental and epidemiologic data suggest a role for hormone-related exposures in ovarian carcinogenesis and risk factor ...
Antonia Trichopoulou   +91 more
core   +1 more source

Infectious pericarditis caused by Gemella sanguinis induced by Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA): A case report

open access: yesRespiratory Medicine Case Reports, 2020
A 69-year-old man had experienced right chest pain for several months. Chest computed tomography (CT) showed a right upper lobe lung tumor and swelling of multiple mediastinal and right hilar lymph node.
Takako Inoue   +9 more
doaj   +1 more source

Preventative therapies for healthy women at high risk of breast cancer [PDF]

open access: yes, 2014
Ivana Sestak Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London, UKAbstract: Tamoxifen has been shown to reduce the risk of developing estrogen receptor (ER)-positive ...
Sestak I, Sestak, I
core   +1 more source

The Role of Transabdominal Ultrasound in the Diagnosis of Early Stage Pancreatic Cancer: Review and Single-Center Experience

open access: yesDiagnostics, 2018
Pancreatic cancer (PC) is the fourth leading cause of cancer-related death with a 5-year survival rate less than 10%. In the absence of effective screening methods, such as blood markers, most clinical diagnoses of PC are made at an advanced stage ...
Reiko Ashida   +8 more
doaj   +1 more source

Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk. [PDF]

open access: yes, 2011
BACKGROUND: Somatic mutations in phosphoinositide-3-kinase catalytic subunit alpha (PIK3CA) are frequent in breast tumours and have been associated with oestrogen receptor (ER) expression, human epidermal growth factor receptor-2 overexpression, lymph ...
Dite, G S   +417 more
core   +1 more source

Patients' and oncologists' views on the treatment and care of advanced ovarian cancer in the UK:results from the ADVOCATE study [PDF]

open access: yes, 2013
Background:Most patients presenting with advanced ovarian cancer (AOC) eventually relapse. Symptom palliation, maintenance of quality of life (QoL) and prolongation of life are primary therapeutic goals.Methods:Sixty-six UK oncologists completed an ...
Monson, K   +23 more
core   +1 more source

Novel phosphoinositide 3-kinase/mTOR dual inhibitor, NVP-BGT226, displays potent growth-inhibitory activity against human head and neck cancer cells in vitro and in vivo

open access: yes, 2011
[[abstract]]Purpose: Dysregulation of the phosphoinositide 3-kinase (PI3K)/AKT/mTOR signaling pathway frequently accounts for the tumorigenesis in head and neck cancer.
Chang, KY;Tsai, SY;Wu, CM;Yen, CJ;Chuang, BF;Chang, JY
core   +1 more source

Omega-3 and-6 Fatty Acid Intake and Colorectal Cancer Risk in Swedish Womens Lifestyle and Health Cohort

open access: yes, 2020
Purpose We aimed to assess the association between the dietary intake of fish-derived omega-3 polyunsaturated fatty acids and the risk of colorectal cancer among Swedish women.
Shin, Aesun,   +11 more
core   +1 more source

Early differential responses elicited by BRAFV600E in adult mouse models

open access: yesCell Death and Disease, 2022
The BRAF gene is frequently mutated in cancer. The most common genetic mutation is a single nucleotide transition which gives rise to a constitutively active BRAF kinase (BRAFV600E) which in turn sustains continuous cell proliferation.
Giuseppe Bosso   +5 more
doaj   +1 more source

Salt-inducible kinase 3 expression identifies long-term survivors of serous ovarian cancer

open access: yes, 2019
[[abstract]]Background: Epithelial ovarian cancer (EOC) has a high tumor-associated mortality rate among the gynecological cancers because EOC is usually diagnosed during the advanced stage.
Hsu, KF;Liang, YL;Wu, CH;Shih, NY
core   +1 more source

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