Nicotine mediated epithelial modulations: An in-vitro evidence
Journal of Oral Biology and Craniofacial Research, 2023 Introduction: Nicotine, the main ingredient in tobacco, acts as a key alkaloid of nearly all tobacco products and has been demonstrated to facilitate tumorigenesis and accelerate metastasis.
Jigna Joshi, Apexa Pandit, Franky Shah
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Completeness of case ascertainment and survival time error in English cancer registries: impact on 1-year survival estimates. [PDF]
, 2011 BACKGROUND: It has been suggested that cancer registries in England are too dependent on processing of information from death certificates, and consequently that cancer survival statistics reported for England are systematically biased and too low ...
Riaz, SP +22 more
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Gynecologic Oncology Reports, 2023 Pelvic exenteration (PE) is a highly invasive procedure associated with high morbidity and mortality rates. Laparoscopy is a promising option to reduce this invasiveness, and laparoscopic PE significantly reduces blood loss and shortens hospital stays ...
Hiroyuki Kanao +7 more
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Novel phosphoinositide 3-kinase/mTOR dual inhibitor, NVP-BGT226, displays potent growth-inhibitory activity against human head and neck cancer cells in vitro and in vivo [PDF]
, 2011 [[abstract]]Purpose: Dysregulation of the phosphoinositide 3-kinase (PI3K)/AKT/mTOR signaling pathway frequently accounts for the tumorigenesis in head and neck cancer.
Chang, KY;Tsai, SY;Wu, CM;Yen, CJ;Chuang, BF;Chang, JY
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Omega-3 and-6 Fatty Acid Intake and Colorectal Cancer Risk in Swedish Womens Lifestyle and Health Cohort [PDF]
, 2020 Purpose We aimed to assess the association between the dietary intake of fish-derived omega-3 polyunsaturated fatty acids and the risk of colorectal cancer among Swedish women.
Shin, Aesun, +11 more
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LAG-3 in Cancer Immunotherapy [PDF]
, 2010 LAG-3 (CD223) is a cell surface molecule expressed on activated T cells (Huard et al. Immunogenetics 39:213-217, 1994), NK cells (Triebel et al. J Exp Med 171:1393-1405, 1990), B cells (Kisielow et al. Eur J Immunol 35:2081-2088, 2005), and plasmacytoid dendritic cells (Workman et al.
Monica V, Goldberg, Charles G, Drake
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Salt-inducible kinase 3 expression identifies long-term survivors of serous ovarian cancer [PDF]
, 2019 [[abstract]]Background: Epithelial ovarian cancer (EOC) has a high tumor-associated mortality rate among the gynecological cancers because EOC is usually diagnosed during the advanced stage.
Hsu, KF;Liang, YL;Wu, CH;Shih, NY
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Role of insulin-like growth factor binding protein-3 in 1, 25-dihydroxyvitamin-d 3 -induced breast cancer cell apoptosis. [PDF]
, 2013 Insulin-like growth factor I (IGF-I) is implicated in breast cancer development and 1, 25-dihydroxyvitamin D3 (1, 25-D3) has been shown to attenuate prosurvival effects of IGF-I on breast cancer cells.
Brosseau, C +5 more
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The HDAC6 inhibitor C1A modulates autophagy substrates in diverse cancer cells and induces cell death [PDF]
, 2018 BACKGROUND: Cytosolic Deacetylase HDAC6 is involved in the autophagy degradation pathway of malformed proteins, an important survival mechanism in cancer cells.
Yunqing Li +13 more
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RB1 Heterogeneity in Advanced Metastatic Castration-Resistant Prostate Cancer. [PDF]
, 2019 PURPOSE: Metastatic castration-resistant prostate cancer (mCRPC) is a lethal but clinically heterogeneous disease, with patients having variable benefit from endocrine and cytotoxic treatments.
Crespo, M +19 more
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