Results 11 to 20 of about 3,550,326 (312)
TC3A: The Cancer 3' UTR Atlas. [PDF]
Nucleic Acids Res, 2018 AbstractWidespread alternative polyadenylation (APA) occurs during enhanced cellular proliferation and transformation. Recently, we demonstrated that CFIm25-mediated 3′ UTR shortening through APA promotes glioblastoma tumor growth in vitro and in vivo, further underscoring its significance to tumorigenesis. Here, we report The Cancer 3′ UTR Atlas (TC3A)
Feng X, Li L, Wagner EJ, Li W.
europepmc +3 more sources
International Journal of Molecular Sciences, 2017 Increasing evidence suggests that the water/glycerol channel aquaporin-3 (AQP3) plays a pivotal role in cancer metastasis. AQP3 knockout mice were resistant to skin tumor formation and overexpression correlated with metastasis and poor prognosis in patients with breast or gastric cancer.
Marlar, Saw +3 more
openaire +3 more sources
The Role of Pentraxin 3 in Gastrointestinal Cancers
Cancers, 2023 Gastrointestinal cancers have become a huge problem worldwide as the number of new cases continues to increase. Due to the growing need to explore new biomarkers and therapeutic targets for the detection and treatment of cancerous lesions, we sought to elucidate the role of Pentraxin-3 in the progression of cancerous lesions, as it is involved in the ...
Monika Zajkowska, Barbara Mroczko
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Galectin-3 and cancer stemness [PDF]
Glycobiology, 2018 Over the last few decades galectin-3, a carbohydrate binding protein, with affinity for N-acetyllactosamine residues, has been unique due to the regulatory roles it performs in processes associated with tumor progression and metastasis such as cell proliferation, homotypic/heterotypic aggregation, dynamic cellular transformation, migration and invasion,
Pratima, Nangia-Makker +2 more
openaire +2 more sources
LAG-3 in Cancer Immunotherapy [PDF]
, 2010 LAG-3 (CD223) is a cell surface molecule expressed on activated T cells (Huard et al. Immunogenetics 39:213-217, 1994), NK cells (Triebel et al. J Exp Med 171:1393-1405, 1990), B cells (Kisielow et al. Eur J Immunol 35:2081-2088, 2005), and plasmacytoid dendritic cells (Workman et al.
Monica V, Goldberg, Charles G, Drake
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The HDAC6 inhibitor C1A modulates autophagy substrates in diverse cancer cells and induces cell death [PDF]
, 2018 BACKGROUND: Cytosolic Deacetylase HDAC6 is involved in the autophagy degradation pathway of malformed proteins, an important survival mechanism in cancer cells.
Yunqing Li +13 more
core +1 more source
Safety and Effectiveness of Chemotherapy in Elderly Biliary Tract Cancer Patients
Current Oncology, 2023 The safety and effectiveness of chemotherapy in elderly patients with biliary tract cancer (BTC) remain unclear. Therefore, we retrospectively reviewed patients who underwent chemotherapy for locally advanced, metastatic, or recurrent BTC at our ...
Takeshi Okamoto +12 more
doaj +1 more source
Two cases of spindle cell variant diffuse large B-cell lymphoma of the uterine cervix
Gynecologic Oncology Reports, 2020 Lymphoma with prominent spindle cell features is a morphological variant of diffuse large B-cell lymphoma (DLBCL) and is categorized as a rare variant by the WHO classification.
Hiroko Murata +6 more
doaj +1 more source
Targeting Tumor Mitochondrial Metabolism Overcomes Resistance to Antiangiogenics
Cell Reports, 2016 Epithelial malignancies are effectively treated by antiangiogenics; however, acquired resistance is a major problem in cancer therapeutics. Epithelial tumors commonly have mutations in the MAPK/Pi3K-AKT pathways, which leads to high-rate aerobic ...
Paloma Navarro +11 more
doaj +1 more source
Gynecologic Oncology Reports, 2021 In 2003, Höckel described the laterally extended endopelvic resection (LEER), which may be an effective surgical technique for patients with laterally recurrent cervical cancer (Höckel, 2003).
Hiroyuki Kanao +5 more
doaj +1 more source