Results 11 to 20 of about 23,963,911 (309)
TC3A: The Cancer 3' UTR Atlas. [PDF]
AbstractWidespread alternative polyadenylation (APA) occurs during enhanced cellular proliferation and transformation. Recently, we demonstrated that CFIm25-mediated 3′ UTR shortening through APA promotes glioblastoma tumor growth in vitro and in vivo, further underscoring its significance to tumorigenesis. Here, we report The Cancer 3′ UTR Atlas (TC3A)
Feng X, Li L, Wagner EJ, Li W.
europepmc +4 more sources
Increasing evidence suggests that the water/glycerol channel aquaporin-3 (AQP3) plays a pivotal role in cancer metastasis. AQP3 knockout mice were resistant to skin tumor formation and overexpression correlated with metastasis and poor prognosis in patients with breast or gastric cancer.
Marlar, Saw +3 more
openaire +3 more sources
Galectin-3 and cancer stemness [PDF]
Over the last few decades galectin-3, a carbohydrate binding protein, with affinity for N-acetyllactosamine residues, has been unique due to the regulatory roles it performs in processes associated with tumor progression and metastasis such as cell proliferation, homotypic/heterotypic aggregation, dynamic cellular transformation, migration and invasion,
Pratima, Nangia-Makker +2 more
openaire +2 more sources
The Role of Pentraxin 3 in Gastrointestinal Cancers
Gastrointestinal cancers have become a huge problem worldwide as the number of new cases continues to increase. Due to the growing need to explore new biomarkers and therapeutic targets for the detection and treatment of cancerous lesions, we sought to elucidate the role of Pentraxin-3 in the progression of cancerous lesions, as it is involved in the ...
Monika Zajkowska, Barbara Mroczko
openaire +2 more sources
LAG-3 in Cancer Immunotherapy [PDF]
LAG-3 (CD223) is a cell surface molecule expressed on activated T cells (Huard et al. Immunogenetics 39:213-217, 1994), NK cells (Triebel et al. J Exp Med 171:1393-1405, 1990), B cells (Kisielow et al. Eur J Immunol 35:2081-2088, 2005), and plasmacytoid dendritic cells (Workman et al.
Monica V, Goldberg, Charles G, Drake
openaire +2 more sources
Two cases of spindle cell variant diffuse large B-cell lymphoma of the uterine cervix
Lymphoma with prominent spindle cell features is a morphological variant of diffuse large B-cell lymphoma (DLBCL) and is categorized as a rare variant by the WHO classification.
Hiroko Murata +6 more
doaj +1 more source
In 2003, Höckel described the laterally extended endopelvic resection (LEER), which may be an effective surgical technique for patients with laterally recurrent cervical cancer (Höckel, 2003).
Hiroyuki Kanao +5 more
doaj +1 more source
A 69-year-old man had experienced right chest pain for several months. Chest computed tomography (CT) showed a right upper lobe lung tumor and swelling of multiple mediastinal and right hilar lymph node.
Takako Inoue +9 more
doaj +1 more source
Pancreatic cancer (PC) is the fourth leading cause of cancer-related death with a 5-year survival rate less than 10%. In the absence of effective screening methods, such as blood markers, most clinical diagnoses of PC are made at an advanced stage ...
Reiko Ashida +8 more
doaj +1 more source
The overall burden of cancer in Ireland is increasing, primarily due to population growth and ageing, with the annual number of cases of breast cancer, cervical cancer and colorectal cancer estimated to increase by 50%, 56% and 113% respectively by 2045 ...
National Cancer Registry Ireland (NCRI)
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