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Galectin-3 in cancer

Clinica Chimica Acta, 2014
Galectin-3 (Gal-3) plays important roles in cell proliferation, adhesion, differentiation, angiogenesis and apoptosis in normal and pathologic tissues. Accumulated evidences indicate that Gal-3 is closely involved in tumor cell transformation, migration, invasion and metastasis. In this review, the associations of the expression and localization of Gal-
Lin, Song   +5 more
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Galectin-3 and cancer (Review).

International Journal of Oncology, 2004
Galectin-3 is a pleiotropic carbohydrate-binding protein involved in a variety of normal and pathological biological processes. Its carbohydrate-binding properties constitute the basis for cell-cell and cell-matrix interactions and cancer progression. Modulation of galectin-3 expression in cancer cells has indeed been reported.
Califice, Stéphane   +2 more
openaire   +3 more sources

The functional significance of 14-3-3 proteins in cancer: focus on lung cancer

Hormone Molecular Biology and Clinical Investigation, 2017
Abstract The 14-3-3 family proteins are phosphoserine/phosphothreonine binding proteins constituting a conserved class of proteins which are detected in all eukaryotic cells. In mammalians, 14-3-3 proteins have seven distinct isoforms ( β, γ, ε, η, ζ, σ and
Afshin, Khorrami   +3 more
openaire   +2 more sources

Cardiovascular, pulmonary, and cancer rehabilitation. 3. Cancer rehabilitation

Archives of Physical Medicine and Rehabilitation, 1996
This self-directed learning module highlights several important rehabilitation aspects in the care of persons with cancer. It is part of the chapter on cardiovascular, pulmonary, and cancer rehabilitation in the Self-Directed Physiatric Education Program for practitioners and trainees in physical medicine and rehabilitation.
M J, Brennan   +2 more
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Cardiopulmonary Rehabilitation and Cancer Rehabilitation. 3. Cancer Rehabilitation

Archives of Physical Medicine and Rehabilitation, 2006
This self-directed learning module highlights the treatment and rehabilitation of patients with cancer. It is part of the study guide on cardiac, pulmonary, and cancer rehabilitation in the Self-Directed Physiatric Education Program for practitioners and trainees in physical medicine and rehabilitation.
Michael D, Stubblefield   +2 more
openaire   +2 more sources

The 14-3-3 cancer connection

Nature Reviews Cancer, 2003
14-3-3 proteins regulate many cellular processes that are important in cancer biology, such as apoptosis and cell-cycle checkpoints. There are seven human 14-3-3 genes and one of these, 14-3-3σ, has been directly implicated in the aetiology of human cancer.
openaire   +3 more sources

3′UTR heterogeneity and cancer progression

Trends in Cell Biology, 2023
The majority of human mRNAs generate alternative 3' untranslated regions (UTRs) through various processes, including RNA modifications such as RNA editing, m6A methylation, and alternative polyadenylation (APA), with 3'UTR splicing as an emerging mechanism.
Jia Jia, Chan   +2 more
openaire   +2 more sources

Claudin-3 expression in gastric cancer

Arkhiv patologii, 2020
Claudins are a family of transmembrane proteins which are essential for the formation and maintenance of epithelial tight junctions. Altered expression of claudins may lead to structural and functional damage of tight junctions, which plays an important role in tumorigenesis and cancer progression.
N V, Danilova   +4 more
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Role of type 3 deiodinase in cancer

Expert Opinion on Therapeutic Targets, 2009
Thyroid hormone (TH) influences a wide variety of biological events in vertebrates. Among them, the balance between proliferation and differentiation is crucial in TH action in normal and pathological conditions, including cancer. Thyroid hormone signaling results from the interaction of T3 with nuclear receptors that, in concert with other ...
DENTICE, MONICA   +2 more
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On the role of galectin-3 in cancer apoptosis

Apoptosis, 2005
Galectin-3, a member of the beta-galactoside-binding gene family, is a multifunctional protein implicated in a variety of biological functions, including tumor cell adhesion, proliferation, differentiation, angiogenesis, cancer progression and metastasis.
S, Nakahara, N, Oka, A, Raz
openaire   +2 more sources

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