Results 11 to 20 of about 5,262,481 (310)

Novel Strategies to Address Critical Challenges in Pancreatic Cancer

, 2022
Whereas mortality rates improved for breast and prostate cancer as a result of successful tumour biology-based therapies and biomarkers, mortality rates for pancreatic cancer patients remained stable [...
Elisa Giovannetti, Puik, Jisce R., Kazemier, Geert, Giovannetti, Elisa, Geert Kazemier, Jisce R. Puik, Rutger-Jan Swijnenburg, Swijnenburg, Rutger-Jan   +7 more
core   +1 more source

Systems biology based drug repositioning for development of cancer therapy

, 2021
Drug repositioning is a powerful method that can assists the conventional drug discovery process by using existing drugs for treatment of a disease rather than its original indication.
Turanli, B., Turanli, Beste, Altay, O., Mardinoglu, A., Nielsen, Jens B, Nielsen, J., Turanli, Beste,, Uhlen, M, Mardinoglu, Adil,, Nielsen, J, Uhlen, Mathias,, Arga, Kazim Y., Bor\ue9n, Jan, Turkez, Hasan, Mardinoglu, Adil, Borén, J, Uhlen, Mathias, Uhlen, M., Turanli, B, Turkez, H., Arga, KY, Altay, Ozlem, Altay, Ozlem,, Arga, K. Y., Mardinoglu, A, Borén, Jan,, Arga, Kazim Y.,, Altay, O, Nielsen, Jens B,, Turkez, Hasan,   +29 more
core   +2 more sources

Registered report: Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

eLife, 2014
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012.
David Blum, Samuel LaBarge, Reproducibility Project: Cancer Biology   +2 more
doaj   +1 more source

Registered report: Widespread potential for growth factor-driven resistance to anticancer kinase inhibitors

eLife, 2014
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012.
Edward Greenfield, Erin Griner, Reproducibility Project: Cancer Biology   +2 more
doaj   +1 more source

Registered report: Transcriptional amplification in tumor cells with elevated c-Myc

eLife, 2015
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012.
David Blum, Haiping Hao, Michael McCarthy, Reproducibility Project: Cancer Biology   +3 more
doaj   +1 more source

Registered report: Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

eLife, 2016
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology. The papers,
John Repass, Nimet Maherali, Kate Owen, Reproducibility Project: Cancer Biology   +3 more
doaj   +1 more source

Registered report: Melanoma genome sequencing reveals frequent PREX2 mutations

eLife, 2014
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012.
Denise Chroscinski, Darryl Sampey, Alex Hewitt, Reproducibility Project: Cancer Biology   +3 more
doaj   +1 more source

Registered report: Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

eLife, 2016
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology. The papers,
Ajay Bhargava, Madan Anant, Hildegard Mack, Reproducibility Project: Cancer Biology   +3 more
doaj   +1 more source

Biology of colorectal cancer [PDF]

ecancermedicalscience, 2015
El cáncer colorrectal es un grave problema de salud, un reto para la investigación y un modelo para estudiar los mecanismos moleculares implicados en su desarrollo. Según su incidencia, esta patología se manifiesta en tres formas: familiar, hereditaria y más comúnmente esporádica, aparentemente no asociada a ningún factor hereditario o familiar.
Arvelo, Francisco, Sojo, Felipe, Cotte, Carlos   +2 more
openaire   +2 more sources

Systems oncology : towards patient-specific treatment regimes informed by multiscale mathematical modelling [PDF]

, 2014
The multiscale complexity of cancer as a disease necessitates a corresponding multiscale modelling approach to produce truly predictive mathematical models capable of improving existing treatment protocols.
Gibin Powathil, Powathil, Gibin G., Chaplain, Mark A. J., Swat, Maciej   +3 more
core   +1 more source