Results 41 to 50 of about 61,183 (295)

Potential role of immunological factors in early diagnosis of cancer cachexia in C26 tumor-bearing mice

open access: yesApplied Biological Chemistry, 2019
Cachexia is a wasting syndrome associated with high mortality in cancer patients through inducing the failure of normal metabolism and reducing the efficacy of cancer treatment. Thus, it is critically important to diagnose cancer cachexia early.
Jae Eun Ju   +7 more
doaj   +1 more source

The regulatory approval of anamorelin for treatment of cachexia in patients with non‐small cell lung cancer, gastric cancer, pancreatic cancer, and colorectal cancer in Japan: facts and numbers.

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2021
Anamorelin is a ghrelin receptor agonist that can be administered orally and thought to improve cancer cachexia by improving appetite and increasing serum insulin‐like growth factor‐1. Anamorelin was not approved for use in Europe.
Hidetaka Wakabayashi   +2 more
doaj   +1 more source

Tumor Growth Increases Neuroinflammation, Fatigue and Depressive-like Behavior Prior to Alterations in Muscle Function [PDF]

open access: yes, 2015
Cancer patients frequently suffer from fatigue, a complex syndrome associated with loss of muscle mass, weakness, and depressed mood. Cancer-related fatigue (CRF) can be present at the time of diagnosis, during treatment, and persists for years after ...
Bicer, Sabahattin   +8 more
core   +2 more sources

Clinical Framework for Quality Improvement of Cancer Cachexia

open access: yesAsia-Pacific Journal of Oncology Nursing, 2018
The objective of this article is to introduce the Clinical Framework for Quality Improvement of Cancer Cachexia (Cachexia Care Framework) as a tool to demonstrate the relevance of integrating the clinical components of cancer cachexia and the ...
Clara Granda-Cameron, Mary Pat Lynch
doaj   +1 more source

Understanding Cachexia in Head and Neck Cancer

open access: yesAsia-Pacific Journal of Oncology Nursing, 2021
One of the major comorbidities of cancer and cancer therapy is posing a global health problem in cancer cachexia. Cancer cachexia is now considered a multifactorial syndrome that presents with drastic loss of body weight, anorexia, asthenia, and anemia ...
Sivaramakrishnan Muthanandam   +1 more
doaj   +1 more source

InACTIVatINg cancer cachexia [PDF]

open access: yesDisease Models & Mechanisms, 2011
Summary of and comment on a recent Cell paper entitled ‘Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival’ (Zhou et al., 2010).
openaire   +3 more sources

Storage Conditions and Passages Alter IL-6 Secretion in C26 Adenocarcinoma Cell Lines [PDF]

open access: yes, 2015
The C26 adenocarcinoma tumor line is frequently used to establish peripheral tumors in mice for the study of cancer cachexia and cancer-related fatigue. Recently, we have noticed a progressive decline in the effects of tumor growth on our biological and ...
Devine, Raymond   +3 more
core   +3 more sources

The Role of Nurse in the Multidisciplinary Management of Cancer Cachexia

open access: yesAsia-Pacific Journal of Oncology Nursing, 2021
Cancer cachexia is a complex syndrome for which multidisciplinary management through collaboration has the potential to improve patient outcomes and efficiency of care, through the integration of nursing into practice.
Yiyuan Zhao, Dong Pang, Yuhan Lu
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

How and why systemic inflammation worsens quality of life in patients with advanced cancer [PDF]

open access: yes, 2017
Introduction: The presence of an innate host systemic inflammatory response has been reported to be a negative prognostic factor in a wide group of solid tumour types in both the operable and advanced setting, both local and distant.
Dolan, Ross D.   +4 more
core   +1 more source

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