Results 21 to 30 of about 3,014,693 (296)

A multi‐targeted treatment approach to cancer cachexia: Auckland's Cancer Cachexia evaluating Resistance Training (ACCeRT) trial [PDF]

, 2020
Background Cancer cachexia is a condition often seen at diagnosis, throughout anti-cancer treatments and in end-stage nonsmall- cell lung cancer patients.
Rita Sasidharan, Bird, Stephen P., Keogh, Justin W.L., Elaine S. Rogers, Rogers, Elaine S, Rogers, Elaine S., Matthew R. Wood, Stephen P. Bird, Roderick D. MacLeod, Bird, Stephen P, Joanna Stewart, Graeme M. Sequeira, Wood, Matthew R, Bruce Arroll, Arroll, Bruce, Sasidharan, Rita, Sequeira, Graeme M., Keogh, Justin WL, Stewart, Joanna, MacLeod, Roderick D, Justin W.L. Keogh, Wood, Matthew R., Sequeira, Graeme M, MacLeod, Roderick D.   +23 more
core   +1 more source

Cachexia in Cancer Patients: Systematic Literature Review

Asian Journal of Oncology, 2020
Introduction Cachexia in cancer patients, especially in advanced stage, is recently known as an emerging problem. Cachexia occurs in about half of all patients with neoplastic disease.
Timotius I. Hariyanto, Andree Kurniawan
doaj   +1 more source

Dystrophin glycoprotein complex dysfunction:a regulatory link between muscular dystrophy and cancer cachexia [PDF]

, 2005
Cachexia contributes to nearly a third of all cancer deaths, yet the mechanisms underlying skeletal muscle wasting in this syndrome remain poorly defined.
Butchbach, Matthew E R, Burghes, Arthur H M, Guttridge, Denis C, Sahenk, Zarife, Saji, Motoyasu, Acharyya, Swarnali, Ringel, Matthew D, Skipworth, Richard J E, Rafael-Fortney, Jill A, Wang, Huating, Ringel, Matthew D., Hollingsworth, Michael A, Carathers, Micheal, Fearon, Kenneth C H, Butchbach, Matthew E.R., Hollingsworth, Michael A., Muscarella, Peter, Guttridge, Denis C., Rafael-Fortney, Jill A., Skipworth, Richard J.E., Burghes, Arthur H.M., Fearon, Kenneth C.H.   +21 more
core   +1 more source

A systematic review examining the relationship between cytokines and cachexia in incurable cancer [PDF]

, 2022
Cancer cachexia is an unmet clinical need that affects more than 50% of patients with cancer. The systemic inflammatory response, which is mediated by a network of cytokines, has an established role in the genesis and maintenance of cancer as well as in ...
Laird, Barry J, Gallagher, Iain J, Paval, D Robert, Barry J. Laird, Skipworth, Richard J E, James McDonald, D. Robert Paval, the Caledonian Cachexia Collaborative, McDonald, James, Richard J.E. Skipworth, Iain J. Gallagher, Patton, Rebekah, Rebekah Patton   +12 more
core   +1 more source

Molecular biomarker discovery and physiological assessment of skeletal muscle in cancer cachexia [PDF]

, 2014
Cachexia affects up to two thirds of all cancer patients with progressive disease. It is a syndrome characterised by weight-loss, anorexia, fatigue, asthenia, peripheral oedema, and is responsible for around 20% of cancer deaths.
Stephens, Nathan Andrew
core   +3 more sources

A prospective study examining cachexia predictors in patients with incurable cancer [PDF]

, 2019
© 2019 The Author(s). Background: Early intervention against cachexia necessitates a predictive model. The aims of this study were to identify predictors of cachexia development and to create and evaluate accuracy of a predictive model based on these ...
Strasser, Florian, Nabal, Maria, Solheim, Tora S, Laird, Barry J, Vagnildhaug, O. M., Solheim, Tora Skeidsvoll, Baracos, V. E., Kaasa, S., Vagnildhaug, Ola M, Brunelli, Cinzia, Hjermstad, Marianne J., Hjermstad, Marianne Jensen, Kaasa, Stein, Laird, Barry, Vagnildhaug, Ola Magne, Baracos, Vickie, Hjermstad, Marianne J, Solheim, T. S., Wilcock, Andrew, Solheim, Tora S.   +19 more
core   +1 more source

Nutritional, pharmacological and hormonal manipulation of muscle metabolism [PDF]

, 2010
PhDSarcopenia and cachexia occur when there is a deficit between the rates of muscle protein synthesis and breakdown, such that a negative balance exists.
Wilkes, Emilie Anne
core   +4 more sources

Ginsenoside Rb1 can ameliorate the key inflammatory cytokines TNF-α and IL-6 in a cancer cachexia mouse model

BMC Complementary Medicine and Therapies, 2020
Background Cancer cachexia is a severe condition that leads to the death of advanced cancer patients, and approximately 50~80% of cancer patients have cancer cachexia.
Shuai Lu, Yubo Zhang, Huajun Li, Jing Zhang, Yingqian Ci, Mei Han   +5 more
doaj   +1 more source

Bile acid metabolism dysregulation associates with cancer cachexia: roles of liver and gut microbiome

Journal of Cachexia, Sarcopenia and Muscle, 2021
Background Cancer cachexia is a multifactorial metabolic syndrome in which bile acid (BA) metabolism might be involved. The aim of the present study was to clarify the contribution of liver and gut microbiota to BA metabolism disturbance in cancer ...
Lixing Feng, Wanli Zhang, Qiang Shen, Chunxiao Miao, Lijuan Chen, Yiwei Li, Xiaofan Gu, Meng Fan, Yushui Ma, Hui Wang, Xuan Liu, Xiongwen Zhang   +11 more
doaj   +1 more source

Pathophysiology of cancer cachexia [PDF]

Revista do Hospital das Clínicas, 2000
Cancer cachexia is a frequent complication observed in patients with malignant tumors. Although several decades have passed since the first focus on the metabolic dysfunction's associated with cancer, few effective therapeutic interventions have been successfully introduced into the medical armamentarium.
Younes, Riad N., Noguchi, Yoshikazu
openaire   +4 more sources