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Association between dietary fiber intake and cancer cachexia: mediation by inflammatory biomarkers [PDF]
Frontiers in NutritionBackgroundCancer cachexia (CC) is a major cause of death in cancer patients, with chronic inflammation being a key driver. Dietary fiber, a nutrient with strong anti-inflammatory potential, is closely linked to mortality risk in cancer patients. However,
Yan Guo +16 more
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Cancer Cachexia Prevalence Is Underestimated in Medical Records of Patients in a Regional Tertiary Hospital [PDF]
Journal of Cachexia, Sarcopenia and MuscleBackground Widespread lack of awareness and limited real‐world prevalence evidence have impeded cachexia care and research. We hypothesized that healthcare professionals may identify the term cachexia, leading to International Classification of Diseases (
Yann Colardelle +6 more
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Serum and urine metabolomics study reveals a distinct diagnostic model for cancer cachexia
Journal of Cachexia, Sarcopenia and Muscle, 2018 Background Cachexia is a multifactorial metabolic syndrome with high morbidity and mortality in patients with advanced cancer. The diagnosis of cancer cachexia depends on objective measures of clinical symptoms and a history of weight loss, which lag ...
Quan‐Jun Yang +11 more
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Screening Assessment and Therapy Intervention of Cancer Cachexia in Adult Patients——Based on the Interpretation of Cancer Cachexia in Adult Patients: ESMO Clinical Practice Guidelines [PDF]
Zhongguo quanke yixue, 2023 Cancer cachexia is a cancer-related, multi-factorial, irreversible clinical syndrome characterized by progressive nutritional consumption, which greatly reduces the survival expectation and quality of life of cancer patient.
WANG Rui, WANG Xiaomei, PENG Guoqing, YU Huan, WANG Sihan, XIA Jin
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JCSM Rapid Communications, 2022 Background Cancer patients who exhibit cachexia lose weight and have low treatment tolerance and poor outcomes compared with cancer patients without weight loss.
Jeffery M. Chakedis +7 more
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QJM: An International Journal of Medicine, 2005 Cancer cachexia is a severe debilitating disorder for which there are currently few therapeutic options. It is driven by the release of pro-inflammatory cytokines and cachectic factors by both host and tumour. Over the past few years, basic science advances have begun to reveal the breadth and complexity of the immunological mechanisms involved, and in
J N, Gordon, S R, Green, P M, Goggin
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Targeting cancer cachexia: Molecular mechanisms and clinical study
MedComm, 2022 Cancer cachexia is a complex systemic catabolism syndrome characterized by muscle wasting. It affects multiple distant organs and their crosstalk with cancer constitute cancer cachexia environment. During the occurrence and progression of cancer cachexia,
Yong‐Fei Wang +3 more
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Journal of Parenteral and Enteral Nutrition, 1988 Cancer cachexia describes a syndrome of progressive weight loss, anorexia, and persistent erosion of host body cell mass in response to a malignant growth. Although often associated with preterminal patients bearing disseminated disease, cachexia may be present in the early stages of tumor growth before any signs or symptoms of malignancy. A decline in
K A, Kern, J A, Norton
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Journal of Cachexia, Sarcopenia and Muscle, 2021 Backgrounds Hand grip strength (HGS) is one of diagnose criteria factors of sarcopenia and is associated with the survival of patients with cancer. However, few studies have addressed the association of HGS and 1 year mortality of patients with cancer ...
Mengmeng Song +16 more
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The Adipokines in Cancer Cachexia [PDF]
International Journal of Molecular Sciences, 2020 Cachexia is a devastating pathology induced by several kinds of diseases, including cancer. The hallmark of cancer cachexia is an extended weight loss mainly due to skeletal muscle wasting and fat storage depletion from adipose tissue. The latter exerts key functions for the health of the whole organism, also through the secretion of several adipokines.
Mannelli M. +3 more
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