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Postępy Higieny i Medycyny Doświadczalnej, 2012 Cancer stem cell theory gains increasingly greater significance in the world of medicine. Numerous findings of scientific research in vivo and in vitro indicate that it is the population of undifferentiated, self-renewing cells which is responsible for recurrence of cancer and metastasis. Similarly to normal stem cells, cancer stem cells (CSC) function
Katarzyna, Wieczorek +1 more
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New England Journal of Medicine, 2006 International ...
Wion, Didier, Berger, François, R.
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Stem cells, cancer, and cancer stem cells [PDF]
Nature, 2001 Stem cell biology has come of age. Unequivocal proof that stem cells exist in the haematopoietic system has given way to the prospective isolation of several tissue-specific stem and progenitor cells, the initial delineation of their properties and expressed genetic programmes, and the beginnings of their utility in regenerative medicine.
Reya, T. +3 more
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Chinese Journal of Lung Cancer, 2023 With the development of precision diagnosis and treatment for non-small cell lung cancer (NSCLC), the epidermal growth factor receptor (EGFR) exon 20 insertion (ex20ins) mutations, as a rare subset of EGFR mutaions, have gradually attracted attention ...
Chinese Society of Clinical Oncology (CSCO) Non-small Cell Lung Cancer Committee
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In Vitro Anticancer Drug Sensitivity Sensing through Single-Cell Raman Spectroscopy
Biosensors, 2021 Traditional in vitro anticancer drug sensitivity testing at the population level suffers from lengthy procedures and high false positive rates. To overcome these defects, we built a confocal Raman microscopy sensing system and proposed a single-cell ...
Jingkai Wang +7 more
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Biomedicines, 2021 “Jekyll and Hyde” refers to persons with an unpredictably dual personality, who are battling between good and evil within themselves In this regard, even cells consist of good and evil counterparts.
Wan Safwani Wan Kamarul Zaman +2 more
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U1 snRNP regulates cancer cell migration and invasion in vitro
Nature Communications, 2020 Stimulated cells and cancer cells have widespread shortening of mRNA 3’-untranslated regions (3’UTRs) and switches to shorter mRNA isoforms due to usage of more proximal polyadenylation signals (PASs) in introns and last exons. U1 snRNP (U1), vertebrates’
Jung-Min Oh +10 more
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Oxidative Stress in Cancer Cell Metabolism
Antioxidants, 2021 Reactive oxygen species (ROS) are important in regulating normal cellular processes whereas deregulated ROS leads to the development of a diseased state in humans including cancers.
Saniya Arfin +7 more
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A Novel Role of the TRPM4 Ion Channel in Exocytosis
Cells, 2022 Under physiological conditions, the widely expressed calcium-activated TRPM4 channel conducts sodium into cells. This sodium influx depolarizes the plasma membrane and reduces the driving force for calcium entry.
Paulina Stokłosa +2 more
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Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy
Nature Biomedical Engineering, 2021 Malignant transformation and tumour progression are associated with cancer-cell softening. Yet how the biomechanics of cancer cells affects T-cell-mediated cytotoxicity and thus the outcomes of adoptive T-cell immunotherapies is unknown.
Kewen Lei +15 more
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