Anti-Proliferative and Pro-Apoptotic Effects of Digested Aglianico Grape Pomace Extract in Human Colorectal Cancer Cells [PDF]
, 2022 Giusy Rita Caponio +11 more
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Autophagy and cancer: Modulation of cell death pathways and cancer cell adaptations
Journal of Cell Biology, 2019 Towers et al. review the complex roles of autophagy in cancer and how autophagy relates to mechanisms of cancer cell death and tumor immunology.
C. Towers, Darya Wodetzki, A. Thorburn
semanticscholar +1 more source
Cancer stem cells in esophageal squamous cell cancer.
Oncology letters, 2019 Cancer stem cells (CSCs) are hypothesized to govern the origin, progression, drug resistance, recurrence and metastasis of human cancer. CSCs have been identified in nearly all types of human cancer, including esophageal squamous cell cancer (ESCC). Four major methods are typically used to isolate or enrich CSCs, including: i) fluorescence-activated ...
Wu, Qian +8 more
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The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Consensus on Application of Third-generation EGFR-TKI in EGFR Mutated NSCLC (2022 Version)
Chinese Journal of Lung Cancer, 2022 Chinese Society of Clinical Oncology (CSCO) Non-small Cell Lung Cancer Committee +1 more
doaj +1 more source
Linker Histones Maintain Genome Stability and Drive the Process of Cellular Ageing
Frontiers in Bioscience-LandmarkAgeing comprises a cascade of processes that are inherent in all living creatures. There are fourteen general hallmarks of cellular ageing, the majority of which occur at a molecular level.
George Miloshev +3 more
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Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumors
Nature Cell Biology, 2018 As oxygen is essential for many metabolic pathways, tumour hypoxia may impair cancer cell proliferation1–4. However, the limiting metabolites for proliferation under hypoxia and in tumours are unknown.
J. Garcia-Bermudez +11 more
semanticscholar +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
The Latest Look at PDT and Immune Checkpoints
Current Issues in Molecular BiologyPhotodynamic therapy (PDT) can not only directly eliminate cancer cells, but can also stimulate antitumor immune responses. It also affects the expression of immune checkpoints. The purpose of this review is to collect, analyze, and summarize recent news
David Aebisher +2 more
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LncRNA XIST/miR-34a axis modulates the cell proliferation and tumor growth of thyroid cancer through MET-PI3K-AKT signaling [PDF]
, 2018 Hua Liu +4 more
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