Results 131 to 140 of about 85,373 (307)

Cancer de mama analisis y resultados de 75 casos

, 2017
Sé han estudiado retrospectivamente 75 casos de cáncer de mama, una de las localizaciones neoplásicas más frecuentes en el país, atendidos en el Servicio de Oncología del Hospital “Carlos Andráde Marín” de Quitó, durante un período de 5 años, de 1979 a 1983.
Pacheco Ojeda, Luis, Guerron, Miguel, Bueno, Cesar, Checa, Fernando, Granja Mena, Luis, Chavez, Vicente, León, Eduardo, Patricio León, Patricio   +7 more
openaire   +1 more source

A Avaliação da usabilidade de um sistema médico inteligente: BCCT.core [PDF]

, 2009
A avaliação estética da mama é um requisito em diversas aplicações médicas, nomeadamente no tratamento conservador do cancro da mama. Para ultrapassar as limitações de reprodutibilidade e praticabilidade dos métodos subjectivos correntes, foi ...
Afonso, Ana P., Cardoso, Jaime S., Cardoso, Maria João, Pérez Cota, Manuel   +3 more
core  

Multi‐Organelle Stress‐Induced Paraptosis by a ROS‐Amplifying Nanocatalyst for Enhanced Cancer Immunotherapy

Advanced Science, EarlyView.
The engineered TF‐Fe@LC nanoplatform programs paraptotic death via multipath ROS amplification that disrupts redox homeostasis, provoking mitochondrial dysfunction, autophagic blockade, and ER stress. This caspase‐independent process elicits robust immunogenic cell death, combining with αPD‐L1 to activate systemic CD8+ T‐cell immunity and suppress ...
Zhe Yu, Haozhe Ren, Hua Li, Jinghan Zhao, Miaomiao Cao, Tian Tang, Youbei Qiao, Liting Chen, Tiehong Yang, Hong Wu   +9 more
wiley   +1 more source

Xanthatin Targets CISD1 to Drive Ferroptosis and Mitophagy as a Dual Anticancer Strategy in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu, Haojie Chen, Xiang Li, Jingxin Liu, Yiwen Li, Zhenyi Shi, Shenshen Guo, Qingfeng Du, Aiping Lu, Daogang Guan   +9 more
wiley   +1 more source

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

Advanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong, Yilei Ma, Yuzhen Gao, Lin Zhou, Luping Lou, Qiang Fang, Sining Fang, Ru Zhao, Jin Zeng, Jun Yang, Guoli Li, Xinyou Xie, Yanzhong Wang, Jun Zhang   +13 more
wiley   +1 more source

The Benefits of Exercise in Breast Cancer. [PDF]

Arq Bras Cardiol, 2022
Campos MDSB, Feitosa RHF, Mizzaci CC, Flach MDRTV, Siqueira BJM, Mastrocola LE.   +5 more
europepmc   +1 more source

Análise dos fatores de risco em mulheres com cancer de mama

Brazilian Journal of Development
O câncer de mama e as doenças cardiovasculares possuem amplo impacto na saúde mundial. De etiologia multifatorial, ambas as doenças podem ser desenvolvidas por hábitos de vida não saudáveis, como o uso de tabaco e álcool, sedentarismo, obesidade e diabetes. Além disso, o câncer de mama pode estar associado a fatores genéticos e reprodutivos.
Gabrielle Feu Pereira, Beatriz Rodrigues Fialho, Rodrigo Alves Faria, Lorena Souza Rittiberg Mauricio, Cleide dos Santos Coelho, Maria Teresa Martins de Araújo, Vinícius Mengal, Sonia Alves Gouvea   +7 more
openaire   +1 more source

GPX4 Inhibitor Resistance and Metastatic Features in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study establishes breast cancer cell lines that are resistant to glutathione peroxidase 4 inhibitors (GPX4i) in vitro and investigates the metastatic capacity of the GPX4i‐resistant versus parental lines in vivo. GPX4i‐resistant cells survive upon intravenous injection, but lose capacity to spontaneously metastasize.
Marie Sabatier, Mayher Kaur, Milena Chaufan, Felix‐Levin Hormann, Luiza Martins Nascentes Melo, Mario Palma, Jordan Torpey, Yanshan Liang, Alanis Carmona, Cameron Fraser, Midori Flores, Krystina J. Szylo, Mahsa Yavari, Sheng Hui, Alpaslan Tasdogan, Sven Heiles, Jessalyn M. Ubellacker   +16 more
wiley   +1 more source

Redox‐Responsive Polymeric Nanocapsules for Enhanced Tumor‐Targeted Delivery of Antimicrobial Peptides

Advanced Science, EarlyView.
This study presents a modular redox‐responsive nanocapsule platform that enables enhanced tumor‐targeted delivery of antimicrobial peptides. Using melittin as an example, the system achieves controlled activation within the tumor microenvironment, improving intratumoral accumulation while minimizing systemic toxicity.
Lin Tang, Yajian Li, Xiaoyin Lv, Jianmei Guo, Yijia Zhang, Yuqi Lin, Kaili Nie, Jian Zeng, Ming Zhang, Qiong Dai   +9 more
wiley   +1 more source

Integralidade do Cuidado à Mulher com Câncer de Mama: Desafios na Implementação da Linha de Cuidado em um Estado do Nordeste do Brasil

Revista Brasileira de Cancerologia
Introdução: O câncer de mama é um problema de saúde pública significativo em razão da alta incidência e mortalidade entre as mulheres. Objetivo: Analisar a integralidade do cuidado à mulher com câncer de mama na Rede de Atenção à Saúde em um Estado do ...
Rosalva Raimundo da Silva, Mauricéa Maria de Santana, Adriana Falangola Benjamin Bezerra, Jurema Telles de Oliveira Lima, Tereza Maciel Lyra   +4 more
doaj   +1 more source