Results 11 to 20 of about 550,657 (156)

HLA-DR in Cytotoxic T lymphocytes predicts breast cancer patients' response to neoadjuvant chemotherapy [PDF]

open access: yes, 2018
Prediction of breast cancer response to Neoadjuvant Chemotherapy (NACT) is an urgent need to promptly direct non-responder patients to alternative therapies.
Borralho, Paula   +4 more
core   +2 more sources

NKG2D and its ligands: one for all, all for one [PDF]

open access: yes, 2018
The activating receptor NKG2D is peculiar in its capability to bind to numerous and highly diversified MHC class I-like self-molecules. These ligands are poorly expressed on normal cells but can be induced on damaged, transformed or infected cells, with ...
Cerboni, Cristina   +7 more
core   +5 more sources

CTLA-4 and PD-1 ligand gene expression in epithelial thyroid cancers [PDF]

open access: yes, 2018
The dysregulation of PD-1 ligands (PD-L1 and PD-L2) and CTLA-4 ligands (CD80 and CD86) represents a tumor strategy to escape the immune surveillance. Here, the expression of PD-L1, PD-L2, CD80 and CD86 was evaluated at mRNA level in 94 patients affected ...
Antonelli, Alessandro   +15 more
core   +3 more sources

Natural killer cell response to chemotherapy-stressed cancer cells: Role in tumor immunosurveillance. [PDF]

open access: yes, 2017
Natural killer (NK) cells are innate cytotoxic lymphoid cells that actively prevent neoplastic development, growth, and metastatic dissemination in a process called cancer immunosurveillance.
Borrelli, Cristiana   +5 more
core   +1 more source

SPARC is a new myeloid-derived suppressor cell marker licensing suppressive activities [PDF]

open access: yes, 2019
Myeloid-derived suppressor cells (MDSC) are well-known key negative regulators of the immune response during tumor growth, however scattered is the knowledge of their capacity to influence and adapt to the different tumor microenvironments and of the ...
Botti L.   +12 more
core   +3 more sources

Memory NK cell features exploitable in anticancer immunotherapy [PDF]

open access: yes, 2019
Besides their innate ability to rapidly produce effector cytokines and kill virus-infected or transformed cells, natural killer (NK) cells display a strong capability to adapt to environmental modifications and to differentiate into long-lived ...
Battella, Simone   +5 more
core   +2 more sources

Natural Killer cells responsiveness to physical esercise: a brief review [PDF]

open access: yes, 2013
Natural killer cells (NK) are a group of peripheral blood lymphocytes which display cytotoxic ac- tivity against a wide range of tumour cells. They are a consistent part of the inflammatory re- sponse that is activated when either internal or external ...
Concu A.   +4 more
core   +1 more source

The iSBTc/SITC primer on tumor immunology and biological therapy of cancer: a summary of the 2010 program

open access: yesJournal of Translational Medicine, 2011
The Society for Immunotherapy of Cancer, SITC (formerly the International Society for Biological Therapy of Cancer, iSBTc), aims to improve cancer patient outcomes by advancing the science, development and application of biological therapy and ...
Urba Walter J   +3 more
doaj   +1 more source

Synthetic immunology: T-cell engineering and adoptive immunotherapy

open access: yesSynthetic and Systems Biotechnology, 2018
During the past decades, the rapidly-evolving cancer is hard to be thoroughly eliminated even though the radiotherapy and chemotherapy do exhibit efficacy in some degree. However, a breakthrough appeared when the adoptive cancer therapy [1] was developed,
Wen Si, Cheng Li, Ping Wei
doaj   +1 more source

Neural regulation of cancer: from mechanobiology to inflammation. [PDF]

open access: yes, 2016
Despite recent progress in cancer research, the exact nature of malignant transformation and its progression is still not fully understood. Particularly metastasis, which accounts for most cancer death, is a very complex process, and new treatment ...
Kim, Tae-Hyung   +2 more
core   +2 more sources

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