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Special Issue: Cancer Metastasis and Therapeutic Resistance
Metastasis and resistance to cancer therapeutics are critical barriers to curing cancer. This special issue entitled “Cancer Metastasis and Therapeutic Resistance” contains nine original contributions.
Elizabeth S. Yeh
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Immunology of Cervical Cancer [PDF]
Optimal function of the immune system allows the recognition and elimination of infected and tumor cells. However, these cells can develop mechanisms to evade the cellular immune response. In human papillomavirus (HPV) infection, dysregulation of major histocompatibility complex Class I molecules and other components of the innate immune system promote
Roberto Jiménez-Lima+5 more
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JTM’s Tumor immunology goes broad: announcing the Immunobiology and Immunotherapy section
For the last four years the Journal of Translational Medicine (JTM) has hosted the Section of Tumor Immunology and Biological Cancer Therapy. Under the editorial leadership of Dr.
Bot Adrian+2 more
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Cancer Immunology and Immunotherapy [PDF]
Hanahan and Weinberg described six distinct biological properties of cancer cells that enable tumor growth and metastasis. These properties were referred to as the traditional hallmarks of cancer. Recent discoveries further elucidated hallmarks including evasion of immune destruction by tumor cells that disrupt anticancer response pathways. This review
Lawrence G Lum+3 more
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Evolutionary paradigm in cancer immunology*
The dynamical system theory in combination with experimental medical data can serve to improve our understanding of how the immune system works and fights the cancer.
Tsygvintsev Alexei
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Senescence and Immunoregulation in the Tumor Microenvironment
Immunotherapies have revolutionized cancer treatment, but despite the many lives that have been extended by these therapies many patients do not respond for reasons that are not well understood.
Megan K. Ruhland, Elise Alspach
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Understanding how murine models can elucidate the mechanisms underlying antitumor immune responses and advance immune-based drug development is essential to advancing the field of cancer immunotherapy.
Andrew Zloza+11 more
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The Natural Killer–Dendritic Cell Immune Axis in Anti-Cancer Immunity and Immunotherapy
Natural killer (NK) cells and dendritic cells (DCs) are crucial mediators of productive immune responses to infection and disease. NK cells and a subtype of DCs, the type 1 conventional DCs (cDC1s), are individually important for regulating immune ...
Erin E. Peterson, Kevin C. Barry
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Summary of the primer on tumor immunology and the biological therapy of cancer
The International Society for Biological Therapy of Cancer (iSBTc) is one of the "premier destinations for interaction and innovation in the cancer biologics community".
Margolin Kim+3 more
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Nano-Enhanced Cancer Immunotherapy: Immunology Encounters Nanotechnology
Cancer immunotherapy utilizes the immune system to fight cancer and has already moved from the laboratory to clinical application. However, and despite excellent therapeutic outcomes in some hematological and solid cancers, the regular clinical use of ...
Ernesto Bockamp+3 more
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