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Veterinary Clinics of North America: Small Animal Practice, 2009
The immune system is generally divided into 2 primary components: the innate immune response, and the highly specific but more slowly developing adaptive or acquired immune response. Immune responses can be further separated by whether they are induced by exposure to a foreign antigen (an "active" response) or whether they are transferred through serum
Constantin N, Baxevanis +2 more
+10 more sources
The immune system is generally divided into 2 primary components: the innate immune response, and the highly specific but more slowly developing adaptive or acquired immune response. Immune responses can be further separated by whether they are induced by exposure to a foreign antigen (an "active" response) or whether they are transferred through serum
Constantin N, Baxevanis +2 more
+10 more sources
Current Opinion in Immunology, 2013
The war on cancer began a little more than 40 years ago as a national research program to radically improve the survival of patients with cancer, a leading cause of death in the United States and worldwide. The main weapons deployed have been surgery, radiation, and chemotherapy, treatments that often carry risks and/or cause adverse side effects ...
KIM YOUNG JUN, PARDOLL DREW M, FU JUAN
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The war on cancer began a little more than 40 years ago as a national research program to radically improve the survival of patients with cancer, a leading cause of death in the United States and worldwide. The main weapons deployed have been surgery, radiation, and chemotherapy, treatments that often carry risks and/or cause adverse side effects ...
KIM YOUNG JUN, PARDOLL DREW M, FU JUAN
+9 more sources
Surgical Oncology Clinics of North America, 2011
Immune-based therapies for cancer are now commonplace. Cytokine therapy, including interferon and interleukin-2, is safe in the community setting. The US Food and Drug Administration has recently approved sipuleucel-T for the treatment of advanced prostate cancer, the first therapeutic cancer vaccine to meet this level of efficacy.
Richard L, White, Asim, Amin
openaire +4 more sources
Immune-based therapies for cancer are now commonplace. Cytokine therapy, including interferon and interleukin-2, is safe in the community setting. The US Food and Drug Administration has recently approved sipuleucel-T for the treatment of advanced prostate cancer, the first therapeutic cancer vaccine to meet this level of efficacy.
Richard L, White, Asim, Amin
openaire +4 more sources
Veterinary Clinics of North America: Small Animal Practice, 2019
The enhanced understanding of immunology experienced over the last 4 decades afforded through the tools of molecular biology has recently translated into cancer immunotherapy becoming one of the most exciting and rapidly expanding fields. Human cancer immunotherapy is now recognized as one of the pillars of treatment alongside surgery, radiation, and ...
openaire +2 more sources
The enhanced understanding of immunology experienced over the last 4 decades afforded through the tools of molecular biology has recently translated into cancer immunotherapy becoming one of the most exciting and rapidly expanding fields. Human cancer immunotherapy is now recognized as one of the pillars of treatment alongside surgery, radiation, and ...
openaire +2 more sources
Biotechnology Journal, 2006
AbstractCancer is the second leading cause of death in the industrialized world. Most cancer patients are treated by a combination of surgery, radiation and/or chemotherapy. Whereas the primary tumor can, in most cases, be efficiently treated by a combination of these standard therapies, preventing the metastatic spread of the disease through ...
Manfred, Schuster +2 more
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AbstractCancer is the second leading cause of death in the industrialized world. Most cancer patients are treated by a combination of surgery, radiation and/or chemotherapy. Whereas the primary tumor can, in most cases, be efficiently treated by a combination of these standard therapies, preventing the metastatic spread of the disease through ...
Manfred, Schuster +2 more
openaire +2 more sources
New England Journal of Medicine, 1977
Control of cancer by immunologic methods was first suggested by physicians who observed, more than a century ago, that advanced cancer occasionally underwent total regression after acute bacterial ...
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Control of cancer by immunologic methods was first suggested by physicians who observed, more than a century ago, that advanced cancer occasionally underwent total regression after acute bacterial ...
openaire +2 more sources
Annals of the New York Academy of Sciences, 1999
Abstract: The goal of cancer treatment is to develop modalities that specifically target tumor cells, thereby avoiding unnecessary side effects to normal tissue. Vaccine strategies that result in the activation of the immune system specifically against proteins expressed by a cancer have the potential to be effective treatment for this purpose.
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Abstract: The goal of cancer treatment is to develop modalities that specifically target tumor cells, thereby avoiding unnecessary side effects to normal tissue. Vaccine strategies that result in the activation of the immune system specifically against proteins expressed by a cancer have the potential to be effective treatment for this purpose.
openaire +2 more sources
Cancer immunotherapy – revisited
Nature Reviews Drug Discovery, 2011Our insight into antitumour immune responses has increased considerably during the past decades, yet the development of immunotherapy as a treatment modality for cancer has been hampered by several factors. These include difficulties in the selection of the optimal dose and schedule, the methods of evaluation, and financial support.
Lesterhuis, W.J. +2 more
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