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Cancer immunotherapy

Biotechnology Journal, 2006
AbstractCancer is the second leading cause of death in the industrialized world. Most cancer patients are treated by a combination of surgery, radiation and/or chemotherapy. Whereas the primary tumor can, in most cases, be efficiently treated by a combination of these standard therapies, preventing the metastatic spread of the disease through ...
Manfred, Schuster   +2 more
openaire   +2 more sources

Cancer immunotherapy – revisited

Nature Reviews Drug Discovery, 2011
Our insight into antitumour immune responses has increased considerably during the past decades, yet the development of immunotherapy as a treatment modality for cancer has been hampered by several factors. These include difficulties in the selection of the optimal dose and schedule, the methods of evaluation, and financial support.
Lesterhuis, W.J.   +2 more
openaire   +3 more sources

Cancer Immunotherapies

Veterinary Clinics of North America: Small Animal Practice, 2019
The enhanced understanding of immunology experienced over the last 4 decades afforded through the tools of molecular biology has recently translated into cancer immunotherapy becoming one of the most exciting and rapidly expanding fields. Human cancer immunotherapy is now recognized as one of the pillars of treatment alongside surgery, radiation, and ...
openaire   +2 more sources

Precision nanomedicine: navigating the tumor microenvironment for enhanced cancer immunotherapy and targeted drug delivery

Molecular Cancer
Cancer treatment has been revolutionized by immunotherapy and nanomedicine, offering innovative strategies to overcome the tumor microenvironment (TME) complexities.
Hussein Sabit   +8 more
semanticscholar   +1 more source

Cancer Immunotherapy

Dermatology, 1978
This paper briefly reviews some mechanisms of tumor immunity and the principles of cancer immunotherapy. Cellular and humoral immunity can both influence tumor cells. Most of the cells belonging to the immune system can act on neoplastic cells. T cells can kill them, macrophages inhibit their growth, and K cells through their Fc receptor also destroy ...
openaire   +2 more sources

Advances in cancer immunotherapy: historical perspectives, current developments, and future directions

Molecular Cancer
Cancer immunotherapy, encompassing both experimental and standard-of-care therapies, has emerged as a promising approach to harnessing the immune system for tumor suppression.
Meiyin Zhang   +8 more
semanticscholar   +1 more source

Bladder Cancer Immunotherapy

Journal of Urology, 1982
A randomized controlled prospective evaluation of intravesical and percutaneous bacillus Calmette-Guerin immunotherapy was done in 57 patients with transitional cell carcinoma of the bladder. In addition, 9 patients at high risk for tumor recurrence were treated with bacillus Calmette-Guerin produced a self-limited cystitis and 1 complication ...
D L, Lamm   +3 more
openaire   +2 more sources

Present and future of cancer nano-immunotherapy: opportunities, obstacles and challenges

Molecular Cancer
Clinically, multimodal therapies are adopted worldwide for the management of cancer, which continues to be a leading cause of death. In recent years, immunotherapy has firmly established itself as a new paradigm in cancer care that activates the body’s ...
Man Wang, Fei Yu, Yuan Zhang
semanticscholar   +1 more source

Corticosteroids and Cancer Immunotherapy.

Clinical Cancer Research, 2023
Despite revolutionizing cancer management, immunotherapies dysregulate the immune system leading to immune-mediated adverse events. These common and potentially dangerous toxicities are often treated with corticosteroids, which are among the most ...
Rachel S Goodman   +2 more
semanticscholar   +1 more source

Combinatorial Cancer Immunotherapies

2016
T cell checkpoint blockade therapies are revolutionizing the treatment of patients with cancer. Highlighted by the recent success of PD-1 plus CTLA-4 blockade in patients with melanomas, synergistic immunotherapy combinations of modalities represent an important opportunity to improve responses and outcomes for patients.
Matthew D, Hellmann   +2 more
openaire   +2 more sources

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