Results 51 to 60 of about 1,083,547 (307)

Increased KCNQ3 expression in papillary thyroid cancer promotes proliferation and migration

Cancer Cell International
Purpose Papillary thyroid cancer (PTC), the most prevalent thyroid malignancy, is witnessing a global surge in incidence. The potassium voltage-gated channel subfamily Q member 3 (KCNQ3) is aberrantly overexpressed in PTC, yet its mechanistic ...
Qiuli Li, Muyuan Liu, Xuhong Song, Lingzhu Xie, Dongchen Liu, Ting Su, Yangzhan Xu, Gengquan Li, Bin Liang, Dongyang Huang   +9 more
doaj   +1 more source

Oncology Nursing in Singapore: How It Evolved and What Does the Future Hold?

Asia-Pacific Journal of Oncology Nursing, 2020
Cancer is the leading cause of death in Singapore since the early 1980s and has remained so since then, accounting for 29.7% of deaths in 2015. Rapid technological advancements in the treatment of cancer and the development of the specialty of radiation ...
Gek Phin Chua
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Cancer incidence and mortality in France over the period 1980-2005.

, 2008
BACKGROUND: The objective of this study was to provide updated estimates of national trends in cancer incidence and mortality for France for 1980-2005. METHODS: Twenty-five cancer sites were analysed.
Belot, A, Troussard, Xavier,, Bara, S, Hédelin, G, Raverdy, Nicole, Daubisse, L, Collignon, A, Arveux, Patrick, Trétarre, B, Faivre, Jean, Chérié-Challine, Laurence, Velten, M., Grosclaude, P, Colonna, Marc, Delafosse, Patricia, Monnereau, A, Benhamou, Ellen, Bovet, Martine, Molinié, F, Janoray, I, Bouvier, Anne Marie, Launoy, G, Grosclaude, Pascale, Bara, Simona, Monnereau, Alain, A., Troussard, Xavier, X., Le Stang, N, Maynadié, Marc, Janoray, Inès, Daubisse, Laetitia, Delafosse, P, Estève, J, Faivre, J, Monnereau, Alain,, Esteve, Jaume, Schvartz, C, Trétarre, Brigitte, Colonna, M, Bovet, M, Binder-Foucard, F, Bouvier, A-M, Hédelin, Guy, Collignon, Anne, Maynadié, M, Molinié, Florence, Remontet, L, Buemi, A, Belot, Aurélien, Schvartz, Claire, Launoy, Guy, Jougla, Eric, Danzon, Arlette, Troussard, X, Bossard, N, Guizard, A-V, Arveux, P, Jougla, E, Le Stang, Nolwenn, Benhamou, E, Raverdy, N, Binder-Foucard, Florence, Danzon, A, Velten, M, Guizard, Anne Valérie, Chérié-Challine, L, Remontet, L., Buemi, Antoine, Bossard, Nadine   +67 more
core   +1 more source

Incidence of cancer in Navarra

Anales del Sistema Sanitario de Navarra, 2009
The data on the incidence of cancer in Navarra for the two year period 1993-94 is set out by age groups and sex, with the aim of making available the most recent information contained in the Navarra Cancer Register. The collection of data for the years 1993-94 was carried out in an active manner in the information sources of the register.
openaire   +3 more sources

Nuclear ANLN regulates transcription initiation related Pol II clustering and target gene expression

Nature Communications
Anillin (ANLN), a mitotic protein that regulates contractile ring assembly, has been reported as an oncoprotein. However, the function of ANLN in cancer cells, especially in the nucleus, has not been fully understood.
Yu-Fei Cao, Hui Wang, Yong Sun, Bei-Bei Tong, Wen-Qi Shi, Liu Peng, Yi-Meng Zhang, Yu-Qiu Wu, Teng Fu, Hua-Yan Zou, Kai Zhang, Li-Yan Xu, En-Min Li   +12 more
doaj   +1 more source

The effectiveness of problem-based learning (PBL) in enhancing critical thinking skills in medical education: a systematic review and meta-analysis

Frontiers in Education
BackgroundProblem-based learning (PBL) has emerged as a transformative educational strategy aimed at enhancing critical thinking in medical education.
Ting Su, Jing Liu, Lele Meng, Yijing Luo, Qiaoling Ke, Lingzhu Xie, Lingzhu Xie   +6 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Increasing incidence of thyroid cancer in shanghai, China, 1983-2007

, 2011
Increasing incidences of thyroid cancer were observed in some countries, like USA, UK, France, etc. Jointpoint regression was used to analyze the incidence of thyroid cancer in Shanghai, China, from 1983 to 2007.
Youxin Wang, Wei Wang
core   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source