Results 51 to 60 of about 4,964,098 (260)

GASTROINTESTINAL CANCER STATISTICS

Сибирский онкологический журнал, 2017
The purpose of the study was to analyze the incidence and mortality rates of gastrointestinal cancer, and to provide data on the current state of cancer care for these patients. Material and methods. The crude and age-standardized incidence and mortality
E. M. Axel
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

ECOLOGICAL-GEOGRAPHICAL FEATURES OF MORBIDITY MALIGNANT NEOPLASMS OF THE POPULATION OF THE CHECHEN REPUBLIC

Юг России: экология, развитие, 2014
Presents an analysis of long-term data on cancer incidence of the population of theChechenRepublic. Examines the state of water quality in districts and cities of the Republic to reveal in these areas carcinogenic and carcinogenic factors of the ...
G. M. Abdurakhmanov, T. N. Ashurbekova
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

ITGA3–MET interaction promotes papillary thyroid cancer progression via ERK and PI3K/AKT pathways

Annals of Medicine
Background Studies have examined the role of integrin α3 (ITGA3) in papillary thyroid carcinoma (PTC). However, the functional and molecular mechanism by which ITGA3 is involved in the progression of PTC remains poorly understood.Methods To investigate ...
Youmian Lan, Dongchen Liu, Bin Liang, Xuhong Song, Lingzhu Xie, Hanwei Peng, Haipeng Guo, Chaoqun Hong, Xuwu Weng, Xiaolong Wei, Xiaoqi Liao, Rui Liang, Dongyang Huang, Muyuan Liu   +13 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Cancer incidence and mortality among Ohio residents (Online); Other title: Title from OCISS reports index screen: Ohio cancer incidence and mortality report, an analysis of incidence and mortality data

, 2011
Annual; 1997/2001-; "The Ohio Department of Health [and] Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University."; Vol.

core  

Incidence and survival of oesophageal and gastric cancer in England between 1998 and 2007, a population-based study. [PDF]

, 2012
BACKGROUND: Major changes in the incidence of oesophageal and gastric cancers have been reported internationally. This study describes recent trends in incidence and survival of subgroups of oesophageal and gastric cancer in England between 1998 and 2007
Hardwick, Richard H, Blazeby, Jane M, Jane M Blazeby, Elizabeth A Davies, Davies, Elizabeth A; id_orcid, Victoria H Coupland, Møller, Henrik; id_orcid, Coupland, Victoria H, Henrik Møller, Karen M Linklater, Møller, Henrik, Richard H Hardwick, Linklater, Karen M, Michael A Mendall, William Allum, Allum, William, Davies, Elizabeth A, Mendall, Michael A   +17 more
core   +2 more sources