Results 61 to 70 of about 4,964,098 (260)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Temporal upregulation of TREM2 parallel to M2 macrophage marker expression in tuberculosis: implications for macrophage polarization regulation

Frontiers in Cellular and Infection Microbiology
BackgroundThis study aims to explore the association between Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) expression and tuberculosis pathogenesis, with particular focus on its potential correlation with established macrophage polarization ...
Xiaoqian Shang, Naifeisha Maimaiti, Fengming Tian, Chunbo Liao, Hu Sun, Xuan Zhou, Weina Kong, Qiannan Sun, Liang Wang, Xiumin Ma   +9 more
doaj   +1 more source

Ohio Cancer Incidence Surveillance System record

, 2007
Quarterly; Vol. 1, issue 2 [i.e. issue 1] (Winter 2007)-; Description based on: Winter 2007; title from caption (viewed on July 24, 2008).; latest issue consulted: Vol. 2, issue 1 (Spring 2008).; Winter 2007 and Spring 2007 both called v.
Ohio Cancer Incidence Surveillance System.
core  

Colorectral cancer incidence, mortality, treatment and survival in Ireland 1994-2010 [PDF]

, 2013
This report describes incidence, mortality, treatment and survival for colorectal cancer in Ireland for the period 1994-2010. Colorectal cancer made up 11% of all cancers in women and 14% in men in 2007-2009, making it the second most common cancer in ...
McDevittt, Joe, Comber, Harry, Walsh, Paul   +2 more
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Pancreatic cancer mortality trends attributable to high fasting blood sugar over the period 1990–2019 and projections up to 2040

Frontiers in Endocrinology
BackgroundPancreatic cancer (PC) is a prevalent malignancy within the digestive system, with diabetes recognized as one of its well-established risk factors.MethodsData on PC mortality attributed to high fasting blood sugar were retrieved from the Global
Yongguang Wei, Yongguang Wei, Yongguang Wei, Zedong Qin, Xiwen Liao, Xiwen Liao, Xiwen Liao, Xin Zhou, Xin Zhou, Xin Zhou, Huasheng Huang, Huasheng Huang, Huasheng Huang, Chenlu Lan, Chenlu Lan, Chenlu Lan, Wei Qin, Wei Qin, Wei Qin, Guangzhi Zhu, Guangzhi Zhu, Guangzhi Zhu, Hao Su, Hao Su, Hao Su, Tao Peng, Tao Peng, Tao Peng   +27 more
doaj   +1 more source

Ohio cancer incidence and mortality report, an analysis of incidence and mortality data

, 2009
Annual; 1997/2001-; "The Ohio Department of Health [and] Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University."; Vol.

core  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

The Mechanism of HPV-mediated DNA Methylation in the Promoter Region of Long-chain Non-coding RNA MAGI2-AS3 in the Occurrence and Development of Cervical Cancer

Clinical and Experimental Obstetrics & Gynecology
Background: Cervical cancer, a malignancy of gynecological origin, typically necessitates a therapeutic approach combining surgery and chemoradiotherapy as the primary intervention.
Jie Zhang, Qiong Xia, Qinghua Zhang
doaj   +1 more source