Results 31 to 40 of about 897,136 (317)
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Does shear wave ultrasound independently predict axillary lymph node metastasis in women with invasive breast cancer? [PDF]
Shear wave elastography (SWE) shows promise as an adjunct to greyscale ultrasound examination in assessing breast masses. In breast cancer, higher lesion stiffness on SWE has been shown to be associated with features of poor prognosis.
Thomson, Kim +17 more
core +1 more source
Background Platinum-based chemotherapy is commonly used to treat non-small cell lung cancer (NSCLC); however, innate and acquired resistance is clinically seen in many patients.
Ji Hae Lee +4 more
doaj +1 more source
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
Discovery of novel MKL1 target genes important for cancer progression and metastasis : a focus on WNT1 inducible signaling pathway protein 1 (WISP1/CCN4) [PDF]
Tenascin-C (TNC) is involved in tumor initiation and metastasis, and high TNC expression has been associated with poor prognosis in cancers such as glioma, breast, colon and lung carcinoma (Orend and Chiquet-Ehrismann, 2006; Oskarsson, 2013).
Gürbüz, Irem
core +1 more source
Background: Venous thromboembolism (VTE) is a potential complication among lymphoma patients. We evaluated the incidence rate and predictors of VTE in lymphoma patients undergoing chemotherapy.Methods: The present study retrospectively studied 1,069 ...
Yue Chen +9 more
doaj +1 more source
Lymphangiogenesis and cancer metastasis
Lymphangiogenesis remains a fascinating biological process that plays a crucial role in both normal tissue development and several lymphatic diseases. The last few years have witnessed a rapid progression in understanding the development and regulation of the lymphatic system which provided insight on several pathological processes including cancer ...
Mahir A A, Al-Rawi, Wen G, Jiang
openaire +2 more sources
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman +7 more
wiley +1 more source
ESM1 Interacts with c-Met to Promote Gastric Cancer Peritoneal Metastasis by Inducing Angiogenesis
The peritoneum is the most common metastatic site of advanced gastric cancer and is associated with extremely poor prognosis. Endothelial-specific molecule 1 (ESM1) was found to be significantly associated with gastric cancer peritoneal metastasis (GCPM);
Tao Chen +9 more
core +1 more source
Anti-S100A4 Antibody Suppresses Metastasis Formation by Blocking Stroma Cell Invasion
The small Ca-binding protein, S100A4, has a well-established metastasis-promoting activity. Moreover, its expression is tightly correlated with poor prognosis in patients with numerous types of cancer.
Jörg Klingelhöfer +6 more
doaj +1 more source

