Results 51 to 60 of about 26,447,258 (401)

Redefining cancer research for therapeutic breakthroughs

British Journal of Cancer
Cancer research has played a pivotal role in improving patient outcomes. However, despite the significant investment in fundamental cancer research over the past few decades, the translation of funding into substantial advancements in cancer treatment ...
Arseniy E Yuzhalin
semanticscholar   +1 more source

Isolation and characterization of exosomes for cancer research

Journal of Hematology & Oncology, 2020
Exosomes are a subset of extracellular vesicles that carry specific combinations of proteins, nucleic acids, metabolites, and lipids. Mounting evidence suggests that exosomes participate in intercellular communication and act as important molecular ...
Le Zhu, Hao Sun, Shun Wang, Sheng-Lin Huang, Yan Zheng, Chaoqun Wang, Beiyuan Hu, Wei Qin, T. Zou, Yan Fu, Xiaotian Shen, Wenwei Zhu, Yan Geng, Lu Lu, H. Jia, L. Qin, Q. Dong   +16 more
semanticscholar   +1 more source

Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx® Digital Spatial Profiler

Cancers, 2021
Simple Summary In breast cancer, there is a high degree of variability in tumors and the surrounding tissue called the tumor microenvironment (TME). To better understand tumor biology and metastasis, as well as to predict response to cancer treatments or
Helga Bergholtz, J. Carter, A. Cesano, M. Cheang, S. Church, P. Divakar, C. Fuhrman, S. Goel, J. Gong, Jennifer L. Guerriero, M. Hoang, E. Hwang, H. Kuasne, Jinho Lee, Yan Liang, E. Mittendorf, J. Perez, A. Prat, L. Pusztai, J. Reeves, Y. Riazalhosseini, J. Richer, Ö. Sahin, Hiromi Sato, I. Schlam, T. Sørlie, D. Stover, S. Swain, A. Swarbrick, E. Thompson, S. Tolaney, S. Warren, On Behalf Of The GeoMx Breast Cancer Consortium   +32 more
semanticscholar   +1 more source

Humphrey Center News: Spring 1988 v. 3, no. 1 [PDF]

, 1988
Newsletter of the Hubert H.
Hubert H. Humphrey Cancer Research Center of Boston University, Lupfer, Caroline H.   +1 more
core   +1 more source

Three-Dimensional Spheroids as In Vitro Preclinical Models for Cancer Research

Pharmaceutics, 2020
Most cancer biologists still rely on conventional two-dimensional (2D) monolayer culture techniques to test in vitro anti-tumor drugs prior to in vivo testing.
Bárbara Pinto, Ana C. Henriques, Patrícia M. A. Silva, H. Bousbaa   +3 more
semanticscholar   +1 more source

Technologies for Cancer Research [PDF]

Biomedical Journal of Scientific & Technical Research, 2020
From an ever wider collection of scientific publications and from the continuous updates provided by the mass media, it is clear how the interconnection between technology and oncology is now close and profitable...
openaire   +4 more sources

Advances in Preventive Therapy for Estrogen-Receptor-Negative Breast Cancer. [PDF]

, 2014
Preventing breast cancer is an effective strategy for reducing breast cancer deaths. The purpose of chemoprevention (also termed preventive therapy) is to reduce cancer incidence by use of natural, synthetic, or biological agents.
Brown, Powel H, Litzenburger, Beate C
core   +1 more source

Microfluidic Technologies in Advancing Cancer Research

Micromachines
This review explores the significant role of microfluidic technologies in advancing cancer research, focusing on the below key areas: droplet-based microfluidics, organ-on-chip systems, paper-based microfluidics, electrokinetic chips, and microfluidic ...
Arjun Ajikumar, Kin Fong Lei
doaj   +1 more source

Comprehensive genomic characterization defines human glioblastoma genes and core pathways. [PDF]

, 2008
Human cancer cells typically harbour multiple chromosomal aberrations, nucleotide substitutions and epigenetic modifications that drive malignant transformation.
Cancer Genome Atlas Research Network
core   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source