Results 61 to 70 of about 5,208,219 (312)

Humphrey Center News: Spring 1985 v. 1, no. 1 [PDF]

, 1985
Newsletter of the Hubert H.
Hubert H. Humphrey Cancer Research Center of Boston University
core  

At Short Telomeres Tel1 Directs Early Replication and Phosphorylates Rif1 [PDF]

, 2014
Funding AS was supported by a Cancer Research UK PhD studentship and ORSAS. SK is supported by a Scottish Universities Life Sciences Alliance PhD studentship.
Donaldson, Anne D., Kedziora, Sylwia, Sridhar, Akila   +2 more
core   +4 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Click Chemistry in Human Cancer Research

Zhongliu Fangzhi Yanjiu
As one of the typical bioorthogonal chemistry reactions, click chemistry joins molecules similar to “Lego”. Bioorthogonal click chemistry is used to modify cancer cells, design antitumor drugs, delivery drugs, manipulate immune cells, and help ...
Baihong ZHANG, Hongyun YUE
doaj   +1 more source

Non-selective Primary Human Tumor Cell Line Generation from Surgical Resections to be Paired With Flash Frozen and Paraffin Embedded Tissue: Advancements in Democratizing Translational Research Materials to Rural Institutions

Marshall Journal of Medicine, 2021
Translational cancer research relies on the availability of human patient tissue demonstrating the specific disease process under investigation. Biobanks of human tissue have historically been and remain to date the primary access point for cancer ...
Jennifer Hawkins, Rebecca Russell, Logan Lawrence, Amrita Valluri, Jessica Wellman, Krista Denning   +5 more
doaj   +1 more source

Humphrey Center News: Summer 1985 v. 1, no. 2 [PDF]

, 1985
Newsletter of the Hubert H.
Hubert H. Humphrey Cancer Research Center of Boston University
core  

Mouse models of colorectal cancer. [PDF]

, 2011
Colorectal cancer is one of the most common malignancies in the world. Many mouse models have been developed to evaluate features of colorectal cancer in humans. These can be grouped into genetically-engineered, chemically-induced, and inoculated models.
Koeffler, H Phillip, Tong, Yunguang, Yang, Wancai   +2 more
core   +2 more sources

The inhibitory SAPS3–AMPK interaction detected in HEK293 cells is not detectable in muscle or liver from humans or mice

FEBS Letters, EarlyView.
This study challenges the idea that Sit4‐associated protein subunit 3 (SAPS3) inhibits the energy‐sensing enzyme AMP‐activated protein kinase (AMPK) in muscle and liver tissue. Although SAPS3 interacts with AMPK in cultured cells, we found no such interaction in human or mouse tissues subjected to fasting, exercise, or a high‐fat diet.
Jesper B. Birk, Maria A. Møller, Jørgen F.P. Wojtaszewski, Rasmus Kjøbsted   +3 more
wiley   +1 more source

Non-Fungible Tokens for Organoids: Decentralized Biobanking to Empower Patients in Biospecimen Research

Blockchain in Healthcare Today
Introduction: Scientists use donated biospecimens to create organoids, miniature copies of patient tumors1 that are revolutionizing precision medicine2 and drug discovery.
William Sanchez, Larue Linder, Robert Miller,, Amelia Hood, Marielle Gross   +4 more
doaj   +1 more source

Application and Research Status of <sup>125</sup>I Seeds Brachytherapy in Unresectable Pancreatic Cancer [PDF]

, 2022
Xinxin Duan, Liuyi Yang, Jie Zhou, Ting Xiong, Aixia Sui   +4 more
openalex   +1 more source