Results 61 to 70 of about 24,047,971 (353)
The Cancer Research Campaign [PDF]
Yes. David Lane, co-discoverer of the p53 tumour suppressor, and Mike Stratton, whose team identified and cloned the breast cancer susceptibility gene BRCA2, are two of the 1,300 scientists funded by the CRC.
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Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Macmillan Cancer Support runs an annual grant-funding scheme for UK-based researchers and this year the topics for research proposals are the role of primary care in meeting the needs of people living with cancer, people living with cancer that cannot be cured, and the use of digital technology to improve the experience and outcomes of people living ...
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Introduction: Scientists use donated biospecimens to create organoids, miniature copies of patient tumors1 that are revolutionizing precision medicine2 and drug discovery.
William Sanchez+4 more
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Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
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Recent advances in mass spectrometry based clinical proteomics: applications to cancer research
Cancer biomarkers have transformed current practices in the oncology clinic. Continued discovery and validation are crucial for improving early diagnosis, risk stratification, and monitoring patient response to treatment.
A. Macklin, Shahbaz Khan, T. Kislinger
semanticscholar +1 more source
All information about Cancer for researchers. Cancer biology (cellular and molecular, Genetics, Epigenetics, Metastasis, Metabolism), Causes (Chemicals, Diet and exercise, Infection, Radiation, Heredity, Physical agents, Hormones, Autoimmune diseases), Classification(Carcinoma, Sarcoma, Blastoma, Lymphoma, and leukemia), Treatment (Chemotherapy ...
Aliasghar Tabatabaei mohammadi+6 more
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In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi+5 more
wiley +1 more source
The untapped potential of ascites in ovarian cancer research and treatment
The build-up of fluid in the peritoneal cavity—ascites—is a hallmark of ovarian cancer, the most lethal of all gynaecological malignancies. This remarkable fluid, which contains a variety of cellular and acellular components, is known to contribute to ...
C. Ford+3 more
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Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria+3 more
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