Results 31 to 40 of about 1,024,518 (204)
Epigenetics, 2018 The relationship between CpG content and DNA methylation has attracted considerable interest in recent years. Direct or indirect methods have been developed to investigate their regulatory functions based on various hypotheses, large cohort studies, and ...
Fushun Chen +14 more
doaj +1 more source
Chemical approaches to targeting drug resistance cancer stem cells [PDF]
, 2016 STEMCHEM is a COST action aiming to target causes of drug resistance in cancer stem cells. Cancer stem cells are cells which are believed to be responsible for the larger part of the regenerative capacity of cancers.
Blaire Theuma, Krystle +6 more
core +1 more source
Wnt signalling in intestinal stem cells: lessons from mice and flies [PDF]
, 2018 Adult stem cells play critical roles in the basal maintenance of tissue integrity, also known as homeostasis, and in tissue regeneration following damage. The highly conserved Wnt signalling pathway is a key regulator of stem cell fate.
Carroll, Lynsey +2 more
core +2 more sources
Journal of Translational Medicine, 2017 Background Standardized animal-free components are required for manufacturing cell-based medicinal products. Human platelet concentrates are sources of growth factors for cell expansion but such products are characterized by undesired variability ...
Francesco Agostini +8 more
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Stem Cell Research, 2022 Induced pluripotent stem cell (iPSC) line SCIKFi001-A was reprogrammed from cGMP grade umbilical cord derived mesenchymal stem cells (UC-MSCs) via non-integrating, virus free, self-replicating RNA for eventual use in regenerative medicine.
Ricky Sanjaya +6 more
doaj +1 more source
Reprogramming Cancer Stem Cells [PDF]
Journal of Cancer Science & Therapy, 2012 n ...
Marco Tafani, Matteo Antonio Russo
openaire +2 more sources
New insights from the widening homogeneity perspective to target intratumor heterogeneity
Cancer Communications, 2018 Precision medicine has shed new light on the treatment of heterogeneous cancer patients. However, intratumor heterogeneity strongly constrains the clinical benefit of precision medicine.
Mengying Tong +6 more
doaj +1 more source
Numb Isoforms Deregulation in Medulloblastoma and Role of p66 Isoform in Cancer and Neural Stem Cells [PDF]
, 2018 Numb is an intracellular protein with multiple functions. The two prevalent isoforms, Numb p66 and Numb p72, are regulators of differentiation and proliferation in neuronal development.
Agnese Po +13 more
core +9 more sources
Gastric Cancer Stem Cells [PDF]
Journal of Clinical Oncology, 2008 Cancer stem cells are defined as the unique subpopulation in the tumors that possess the ability to initiate tumor growth and sustain self-renewal as well as metastatic potential. Accumulating evidence in recent years strongly indicate the existence of cancer stem cells in solid tumors of a wide variety of organs.
Shigeo, Takaishi +2 more
openaire +2 more sources
Cancer stem cells in prostate cancer: implications for targeted therapy [PDF]
, 2017 Prostate cancer (PCa) is the most frequently diagnosed cancer in men and the second most common cause of cancer-related mortality among men in the developed world.
Castelo-Branco, Pedro +5 more
core +1 more source