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Cancer systems biology: signal processing for cancer research. [PDF]

open access: yesChin J Cancer, 2011
In this editorial we introduce the research paradigms of signal processing in the era of systems biology. Signal processing is a field of science traditionally focused on modeling electronic and communications systems, but recently it has turned to ...
Yli-Harja O   +3 more
europepmc   +5 more sources

Systems biology and cancer, [Editorial] [PDF]

open access: yesProgress in Biophysics and Molecular Biology, 2011
The systems approach to complex biological problems has rapidly gained ground during the first decade of this century. There are several reasons for this development. An important one is that while the achievement of sequencing the complete human genome,
Maini, Philip   +3 more
core   +7 more sources

ELECANS—an integrated model development environment for multiscale cancer systems biology [PDF]

open access: bronzeBioinform., 2013
MOTIVATION Computational multiscale models help cancer biologists to study the spatiotemporal dynamics of complex biological systems and to reveal the underlying mechanism of emergent properties.
Safee Ullah Chaudhary   +4 more
openalex   +2 more sources

Systems biology analysis of drivers underlying hallmarks of cancer cell metabolism. [PDF]

open access: yesScientific Reports, 2017
Malignant transformation is often accompanied by significant metabolic changes. To identify drivers underlying these changes, we calculated metabolic flux states for the NCI60 cell line collection and correlated the variance between metabolic states of ...
Bordbar, Aarash   +5 more
core   +2 more sources

Systems Biology and Experimental Model Systems of Cancer [PDF]

open access: yesJournal of Personalized Medicine, 2020
Over the past decade, we have witnessed an increasing number of large-scale studies that have provided multi-omics data by high-throughput sequencing approaches.
Gizem Damla Yalcin   +3 more
semanticscholar   +5 more sources

Engineering simulations for cancer systems biology [PDF]

open access: yesCurrent Drug Targets, 2012
Computer simulation can be used to inform in vivo and in vitro experimentation, enabling rapid, low-cost hypothesis generation and directing experimental design in order to test those hypotheses.
Andrews, Paul S.   +8 more
core   +7 more sources

Atlas of Cancer Signalling Network: a systems biology resource for integrative analysis of cancer data with Google Maps [PDF]

open access: goldOncogenesis, 2015
Cancerogenesis is driven by mutations leading to aberrant functioning of a complex network of molecular interactions and simultaneously affecting multiple cellular functions.
Inna Kuperstein   +12 more
openalex   +2 more sources

A Roadmap of Cancer Systems Biology

open access: yesNature Precedings, 2010
What is cancer systems biology? Why should we conduct systems biology research in cancer? What is the relationships between systems biology and personalized medicine? How do we conduct cancer systems biology research?
E. Wang
semanticscholar   +4 more sources

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