Results 11 to 20 of about 1,632,468 (362)

Cancer systems biology: signal processing for cancer research. [PDF]

Chin J Cancer, 2011
In this editorial we introduce the research paradigms of signal processing in the era of systems biology. Signal processing is a field of science traditionally focused on modeling electronic and communications systems, but recently it has turned to ...
Yli-Harja O, Ylipää A, Nykter M, Zhang W.   +3 more
europepmc   +5 more sources

Systems biology and cancer, [Editorial] [PDF]

Progress in Biophysics and Molecular Biology, 2011
The systems approach to complex biological problems has rapidly gained ground during the first decade of this century. There are several reasons for this development. An important one is that while the achievement of sequencing the complete human genome,
Maini, Philip, Noble, Denis, Sonnenschein, C, Soto, AM   +3 more
core   +6 more sources

Mathematical and statistical modeling in cancer systems biology. [PDF]

Front Physiol, 2012
Cancer is a major health problem with high mortality rates. In the post-genome era, investigators have access to massive amounts of rapidly accumulating high-throughput data in publicly available databases, some of which are exclusively devoted to ...
Blair RH, Trichler DL, Gaille DP.
europepmc   +2 more sources

Systems Biology and Experimental Model Systems of Cancer [PDF]

Journal of Personalized Medicine, 2020
Over the past decade, we have witnessed an increasing number of large-scale studies that have provided multi-omics data by high-throughput sequencing approaches.
Gizem Damla Yalcin, Nurseda Danisik, Rana Can Baygin, A. Acar   +3 more
semanticscholar   +4 more sources

A census of pathway maps in cancer systems biology. [PDF]

Nat Rev Cancer, 2020
Kuenzi BM, Ideker T.
europepmc   +2 more sources

Systems biology analysis of drivers underlying hallmarks of cancer cell metabolism. [PDF]

Scientific Reports, 2017
Malignant transformation is often accompanied by significant metabolic changes. To identify drivers underlying these changes, we calculated metabolic flux states for the NCI60 cell line collection and correlated the variance between metabolic states of ...
Bordbar, Aarash, Corbett, Austin J, Jamshidi, Neema, Palsson, Bernhard O, Thomas, Alex, Zielinski, Daniel C   +5 more
core   +2 more sources

Engineering simulations for cancer systems biology [PDF]

Current Drug Targets, 2012
Computer simulation can be used to inform in vivo and in vitro experimentation, enabling rapid, low-cost hypothesis generation and directing experimental design in order to test those hypotheses.
Andrews, Paul S., Bown, James L., Deeni, Yusuf Y., Goltsov, Alexey, Idowu, Michael A., Polac, Fiona A.C., Sampson, Adam T., Shovman, Mark, Stepney, Susan   +8 more
core   +7 more sources

Cancer Systems Biology: a peek into the future of patient care? [PDF]

Nat Rev Clin Oncol, 2014
Werner HM, Mills GB, Ram PT.
europepmc   +2 more sources

Systems Biology Approaches for the Prediction of Possible Role of Chlamydia pneumoniae Proteins in the Etiology of Lung Cancer

PLoS ONE, 2016
Accumulating evidence has recently supported the association of bacterial infection with the growth and development of cancers, particularly in organs that are constantly exposed to bacteria such as the lungs, colon, cervical cancer etc.
Shahanavaj Khan, A. Imran, A. Khan, Mohd Abul Kalam, A. Alshamsan   +4 more
semanticscholar   +3 more sources

Complexity in cancer biology: is systems biology the answer?

Cancer Medicine, 2013
Complex phenotypes emerge from the interactions of thousands of macromolecules that are organized in multimolecular complexes and interacting functional modules. In turn, modules form functional networks in health and disease.
Evangelia Koutsogiannouli, Athanasios G. Papavassiliou, Nikolaos A. Papanikolaou   +2 more
doaj   +4 more sources