Results 241 to 250 of about 1,564,848 (340)

Supplementary Table 1 from The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology

open access: green, 2023
Ogan D. Abaan   +14 more
openalex   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Challenges and opportunities in systems biology education. [PDF]

open access: yesEndocr Relat Cancer
Didier J   +9 more
europepmc   +1 more source

Supplementary Figures 1 - 8 from The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology

open access: green, 2023
Ogan D. Abaan   +14 more
openalex   +2 more sources

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

A global protein–lipid interactome map

open access: yesMolecular Systems Biology, 2010
Marc Brehme, Marc Vidal
doaj   +1 more source

Systems biology analysis of the lung cancer‑related secretome

open access: bronze, 2018
Lin Feng   +6 more
openalex   +2 more sources

Additional file 5 of Evaluation of the potential role of long non-coding RNA LINC00961 in luminal breast cancer: a case–control and systems biology study

open access: gold, 2020
Sepideh Mehrpour Layeghi   +5 more
openalex   +2 more sources

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

Translational studies on pancreatic cancer and gastric cancer: a methodology in PhD thesis. [PDF]

open access: yesFront Pharmacol
Resell M   +7 more
europepmc   +1 more source

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