Results 101 to 110 of about 11,697,511 (307)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Cancer Trends: Cancer of the pancreas

, 2012
Cancer of the pancreas accounts for approximately 2.5% of all invasive cancers and is the 9th most commonly diagnosed cancer in Ireland.1 Almost 400 cases of pancreatic cancer were diagnosed annually between 1994 and 2010 (Table 1).
National Cancer Registry Ireland (NCRI)
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China National Lung Cancer Screening Guideline with Low-dose Computed Tomography (2025 Version)

Chinese Journal of Lung Cancer
Lung cancer remains the leading cause of cancer-related deaths in China. Optimizing lung cancer screening strategies to improve screening efficiency and mitigate associated harms has become a key research focus and priority in current clinical practice ...
Chinese Expert Group on Early Diagnosis and Treatment of Lung Cancer, China Lung Oncology Group   +1 more
doaj   +1 more source

Effects of Raupya Suvarna Sutashekhara, a herbo-mineral-metallic formulation as adjunct Oral Ayurvedic Medicine on long-term survival in patients of malignant brain tumor

Journal of Ayurveda and Integrative Medicine
Background: The incidence of brain tumors poses a significant threat, particularly with high-grade tumors that exhibit rapid growth and can significantly impair the patient's quality of life, despite treatment modalities.
Sadanand Sardeshmukh, Vineeta Deshmukh, Arvind Kulkarni, Swapna Kulkarni, Vasanti Godse, Shrinivas Datar, Sushama Bhuvad, Shweta Gujar, Sameer Gore, Bhagyashree Sardeshmukh, Vinita Awalkanthe, Anita Shingte, Sneha Dalvi, Vijay Radye, Sandeep Chavan   +14 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Cancer Trends: Cancers of the testis

, 2012
An average of 132 cases of testicular cancer was diagnosed per year in Ireland between 1994 and 2010 (Table 1). Almost all cases were microscopically verified (98%) and were germ-cell tumours—57% of which were seminomatous and 40% non-seminomatous ...
National Cancer Registry Ireland (NCRI)
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Gastric ESD may be useful as accurate staging and decision of future therapeutic strategy

Endoscopy International Open, 2017
Background and study aims We sometimes perform gastric endoscopic submucosal dissection (ESD) for total pathologic diagnosis when preoperative diagnosis is difficult.
Ai Fujimoto, Osamu Goto, Toshihiro Nishizawa, Yasutoshi Ochiai, Joichiro Horii, Tadateru Maehata, Teppei Akimoto, Satoshi Kinoshita, Seiji Sagara, Motoki Sasaki, Toshio Uraoka, Naohisa Yahagi   +11 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Diagnosing cancer in an emergency: Patterns of emergency presentation of cancer in Ireland 2002–2015 [PDF]

, 2018
Emergency presentation with cancer can result from lack of awareness of symptoms in patients and is generally associated with more advanced stage, limited treatment options and poorer survival outcomes.
National Cancer Registry Ireland (NCRI), Irish Cancer Society   +1 more
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