Results 71 to 80 of about 11,697,511 (307)

Patient-derived tumor organoids for prediction of cancer treatment response [PDF]

, 2018
Cancer treatment, in particular radiotherapy and chemotherapy, is often hindered by an inherent resistance of cancer cells. Cancer stem cells in particular have previously been shown to be more resistant than other cells within a tumor and are thought ...
Nagle, Peter W., Coppes, Robert P., Coppes, Robert P.; id_orcid, van Luijk, Peter, Plukker, John Th. M., Muijs, Christina T., van Luijk, Peter; id_orcid, Muijs, Christina T.; id_orcid   +7 more
core   +2 more sources

Recurrent UBE3C-LRP5 translocations in head and neck cancer with therapeutic implications

npj Precision Oncology
Head and neck cancer is a major cause of morbidity and mortality worldwide. The identification of genetic alterations in head and neck cancer may improve diagnosis and treatment outcomes.
Bhasker Dharavath, Ashwin Butle, Akshita Chaudhary, Ankita Pal, Sanket Desai, Aniket Chowdhury, Rahul Thorat, Pawan Upadhyay, Sudhir Nair, Amit Dutt   +9 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Cancer Trends: Cervical cancer

, 2017
In the period 2013-2015, invasive cancer of the cervix uteri (ICD10: C53) accounted for just over 1% of all invasive cancers (excluding non-melanoma skin cancer) in Ireland, with an average of 262 cases diagnosed per year.
National Cancer Registry Ireland (NCRI)
core  

Neuroticism and responses to social comparison among cancer patients [PDF]

, 2009
The present study examined how the effects of three audiotapes containig different types of social comparison information on the mood of cancer patients depended on the level of neuroticism.
Buunk, A.P., Van den Bergh, Alfons C. M., van den Bergh, A.C.M., Stiegelis, Heidi E., Sanderman, Robbert, Stiegelis, H.E., Buunk, Abraham P., Sanderman, R., Brakel, Thecla M., Hagedoorn, Mariet, Bennenbroek, Femke T. C., Bennenbroek, F.T.C., Brakel, T.M., Hagedoorn, M.   +13 more
core   +2 more sources

B cell lymphoma 6 promotes hepatocellular carcinoma progression by inhibiting tumor infiltrating CD4+T cell cytotoxicity through ESM1

npj Precision Oncology
Immunotherapy exhibited potential effects for advanced hepatocellular carcinoma, unfortunately, the clinical benefits are often countered by cancer adaptive immune suppressive response.
Jiatao Li, Juan Feng, Ziyong Li, Yuanli Ni, Limei Liu, Xia Lei, Zixuan Chai, Na Zhuang, Jiake Xu, Yongpeng He, Juanjuan Shan, Cheng Qian   +11 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Cancer Trends: Cancer of the liver and biliary tract

, 2010
Liver cancer consists of two main types—hepatocellular carcinoma (HCC) which accounts for about 60% of cases, and intrahepatic bile duct cholangiocarcinoma (ICC), which accounts for about 20%. The liver is one of the less common cancer sites, about 0.
National Cancer Registry Ireland (NCRI)
core  

Do MDM2 SNP309 and TP53 R72P interact in breast cancer susceptibility? A large pooled series from the breast cancer association consortium.

, 2007
Association studies in large series of breast cancer patients can be used to identify single-nucleotide polymorphisms (SNP) contributing to breast cancer susceptibility.
Pharoah, Paul DP, Hogervorst, Frans BL, Dunning, Alison M, Nevanlinna, Heli A, Blomqvist, Carl,, Tommiska, Johanna, Healey, Catherine S, Pharoah, Paul D P, Tollenaar, Rob A E M, Reincke, Scarlett, Peto, Julian, Blomqvist, Carl, Van't Veer, Laura J, Johnson, Nichola, Fletcher, Olivia, Tollenaar, Rob AEM, Broeks, Annegien, Schmidt, Marjanka K, Braaf, Linde M, Hogervorst, Frans B L, Breast Cancer Association Consortium, Easton, Douglas F, Dörk, Thilo   +22 more
core   +1 more source

The systematic analysis of genes related to butyrate metabolism suggests that CDKN3 could serve as a promising therapeutic target for lung adenocarcinoma treatment

BMC Cancer
Background Metabolic pathways are known to significantly impact the development and advancement of lung cancer. This study sought to establish a signature related to butyrate metabolism that is specifically linked to lung adenocarcinoma (LUAD).
Yanchao Luan, Chao Liang, Qingsong Han, Xueqin Zhou, Na Yang, li Zhao   +5 more
doaj   +1 more source