Results 11 to 20 of about 184,119 (211)
Trial results for two COVID-19 vaccines suggest at least 90% efficacy against symptomatic disease (VEDIS). It remains unknown whether this efficacy is mediated by lowering SARS-CoV-2 infection susceptibility (VESUSC) or development of symptoms after ...
David A. Swan +10 more
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1993 represents the 100th anniversary of William Coley's first report of tumor regressions induced by immune system activation in response to bacterial toxins. While many subsequent cancer vaccine trials have yielded tantalizing results, active immunotherapy has not yet become an established modality of cancer therapy.
openaire +4 more sources
Aging, cancer, and cancer vaccines [PDF]
AbstractWorld population has experienced continuous growth since 1400 A.D. Current projections show a continued increase - but a steady decline in the population growth rate - with the number expected to reach between 8 and 10.5 billion people within 40 years.
MAZZOLA, PAOLO +6 more
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Methods to Measure Antibody Neutralization of Live Human Coronavirus OC43
The human Betacoronavirus OC43 is a common cause of respiratory viral infections in adults and children. Lung infections with OC43 are associated with mortality, especially in hematopoietic stem cell transplant recipients.
Jim Boonyaratanakornkit +7 more
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T Cell Subsets in the Germinal Center: Lessons from the Macaque Model
Germinal centers (GCs) are organized lymphoid tissue microstructures where B cells proliferate and differentiate into memory B cells and plasma cells. A few distinctive subsets of highly specialized T cells gain access to the GCs by expressing the B cell
Monica Vaccari, Genoveffa Franchini
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Persistent serum protein signatures define an inflammatory subcategory of long COVID
Long COVID or post-acute sequelae of SARS-CoV-2 (PASC) is a clinical syndrome featuring diverse symptoms that can persist for months following acute SARS-CoV-2 infection.
Aarthi Talla +19 more
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In vivo dynamics of AAV-mediated gene delivery to sensory neurons of the trigeminal ganglia
The ability to genetically manipulate trigeminal ganglion (TG) neurons would be useful in the study of the craniofacial nervous system and latent alphaherpesvirus infections.
Chung H. Dang +7 more
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CXCR3 enables recruitment and site-specific bystander activation of memory CD8+ T cells
T cell bystander activation is induced by systemic inflammation. Here the authors show, using mouse model systems and correlating with human vaccination data, that localized inflammation elicits bystander activation, and that CXCR3 specifically recruits ...
Nicholas J. Maurice +4 more
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Sopp et al describe an approach, which exploits the tailpiece of the naturally multimeric IgM to augment hexamerisation of IgG. Their approach provides a newly engineered format of antibodies for promoting hexamerisation and enhanced complement-dependent
Joshua M. Sopp +10 more
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