Results 21 to 30 of about 334,749 (357)

Persistent serum protein signatures define an inflammatory subcategory of long COVID

open access: yesNature Communications, 2023
Long COVID or post-acute sequelae of SARS-CoV-2 (PASC) is a clinical syndrome featuring diverse symptoms that can persist for months following acute SARS-CoV-2 infection.
Aarthi Talla   +19 more
doaj   +1 more source

Vaccines for Lung Cancer [PDF]

open access: yesJournal of Thoracic Oncology, 2006
Immunotherapy is based on the knowledge that the immune system can distinguish cancerous cells from normal cells. Conceptually, this is an attractive adjuvant approach because it is highly specific and can deal with disseminated disease with minimal impact on normal tissues.
Edward A. Hirschowitz   +2 more
openaire   +3 more sources

T Cell Subsets in the Germinal Center: Lessons from the Macaque Model

open access: yesFrontiers in Immunology, 2018
Germinal centers (GCs) are organized lymphoid tissue microstructures where B cells proliferate and differentiate into memory B cells and plasma cells. A few distinctive subsets of highly specialized T cells gain access to the GCs by expressing the B cell
Monica Vaccari, Genoveffa Franchini
doaj   +1 more source

Costs of delivering human papillomavirus vaccination to schoolgirls in Mwanza Region, Tanzania. [PDF]

open access: yes, 2012
BACKGROUND: Cervical cancer is the leading cause of female cancer-related deaths in Tanzania. Vaccination against human papillomavirus (HPV) offers a new opportunity to control this disease.
Quentin, Wilm   +9 more
core   +5 more sources

Evaluation of Microparticulate Ovarian Cancer Vaccine via Transdermal Route of Delivery [PDF]

open access: yes, 2016
Ovarian cancer is the fifth most commonly occurring malignancy in women, with the highest mortality rate among all the gynecological tumors. Microparticulate vaccine can serve as an immunotherapeutic approach with a promising antigenic delivery system ...
Akalkotkar, Archana   +3 more
core   +2 more sources

Q fever outbreak in the terraced vineyards of Lavaux, Switzerland

open access: yesNew Microbes and New Infections, EarlyView., 2014
Abstract Coxiella burnetii infection (Q fever) is a widespread zoonosis with low endemicity in Switzerland, therefore no mandatory public report was required. A cluster of initially ten human cases of acute Q fever infections characterized by prolonged fever, asthenia and mild hepatitis occurred in 2012 in the terraced vineyard of Lavaux ...
C. Bellini   +9 more
wiley   +1 more source

Cancer Vaccines [PDF]

open access: yesPrimary Care: Clinics in Office Practice, 2011
The term cancer vaccines encompasses 2 different types of vaccines. Prophylactic vaccines block infection by viruses that can alter host DNA and result in cancer. The hepatitis B vaccine and the human papillomavirus vaccines are examples of prophylactic vaccines that can prevent cancer from developing.
openaire   +4 more sources

On-target IgG hexamerisation driven by a C-terminal IgM tail-piece fusion variant confers augmented complement activation

open access: yesCommunications Biology, 2021
Sopp et al describe an approach, which exploits the tailpiece of the naturally multimeric IgM to augment hexamerisation of IgG. Their approach provides a newly engineered format of antibodies for promoting hexamerisation and enhanced complement-dependent
Joshua M. Sopp   +10 more
doaj   +1 more source

Therapeutic cancer vaccines [PDF]

open access: yesJournal of Clinical Investigation, 2015
The clinical benefit of therapeutic cancer vaccines has been established. Whereas regression of lesions was shown for premalignant lesions caused by HPV, clinical benefit in cancer patients was mostly noted as prolonged survival. Suboptimal vaccine design and an immunosuppressive cancer microenvironment are the root causes of the lack of cancer ...
Melief, C.J.M.   +4 more
openaire   +4 more sources

Cancer vaccines in the clinic

open access: yesBioengineering & Translational Medicine, 2023
AbstractVaccines are an important tool in the rapidly evolving repertoire of immunotherapies in oncology. Although cancer vaccines have been investigated for over 30 years, very few have achieved meaningful clinical success. However, recent advances in areas such antigen identification, formulation development and manufacturing, combination therapy ...
Morgan E. Janes   +4 more
openaire   +3 more sources

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