Results 111 to 120 of about 286,222 (357)

Outlook Magazine, Winter 2018 [PDF]

, 2018
https://digitalcommons.wustl.edu/outlook/1206/thumbnail ...

core   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Effect of dendritic cell vaccine on blood redox status in patients with cervical cancer

, 2023
Anna P. Menshenina, I. A. Goroshinskaya, E. M. Frantsiyants, T Moiseenko, Ekaterina V. Verenikina, И. В. Каплиева, Л. А. Немашкалова   +6 more
openalex   +1 more source

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

High seroconversion rate but low antibody titers after two injections of BNT162b2 (Pfizer-BioNTech) vaccine in patients treated with chemotherapy for solid cancers [PDF]

, 2021
Romain Palich, Marianne Veyri, Aurore Vozy, Stéphane Marot, Joseph Gligorov, Marc Antoine Benderra, P. Maingon, Laurence Morand‐Joubert, Z. Adjoutah, Anne‐Geneviève Marcelin, Jean‐Philippe Spano, Jérôme Barrière   +11 more
openalex   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Myeloid Cell Crosstalk Regulates the Efficacy of the DNA/ALVAC/gp120 HIV Vaccine Candidate

Frontiers in Immunology, 2019
Vaccination with DNA-SIV + ALVAC-SIV + gp120 alum results in inflammasome activation, high levels of IL-1β production, emergency myelopoiesis, and the egress of CXCR4+ CD14+ pre-monocytes from bone marrow.
Monica Vaccari, Slim Fourati, Dallas R. Brown, Isabela Silva de Castro, Massimiliano Bissa, Luca Schifanella, Melvin N. Doster, Kathryn E. Foulds, Mario Roederer, Richard A. Koup, Yongjun Sui, Jay A. Berzofsky, Rafick-Pierre Sekaly, Genoveffa Franchini   +13 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Human Melanoma and Glioblastoma Cells Express Cathepsins Supporting Reovirus Moscow Strain Infection

Viruses
This study evaluates the oncolytic potential of the Moscow strain of reovirus against human metastatic melanoma and glioblastoma cells. The Moscow strain effectively infects and replicates within human melanoma cell lines and primary glioblastoma cells ...
Yulia Ammour, Eugenia Nikolaeva, Olesya Sagimbaeva, Pavel Shamsutdinov, Anastasia Astapenko, Yulia Zhelaeva, Marina Gavrilova, Olga Susova, Aleksey Mitrofanov, Ali Bekyashev, Tatiana Nasedkina, Oxana Svitich, Evgeny Faizuloev, Vitaly Zverev   +13 more
doaj   +1 more source

First-in-man application of a novel therapeutic cancer vaccine formulation with the capacity to induce multi-functional T cell responses in ovarian, breast and prostate cancer patients [PDF]

, 2012
Neil L. Berinstein, Mohan Karkada, Michael A. Morse, John Nemunaitis, Gurkamal Chatta, Howard L. Kaufman, Kunle Odunsi, Rita Nigam, Leeladhar Sammatur, Lisa D. MacDonald, Genevieve Weir, Marianne M. Stanford, Marc Mansour   +12 more
openalex   +1 more source