Results 101 to 110 of about 5,770,101 (353)
Biomaterial-enhanced cancer vaccines
Materials & Design, 2022 Cancer vaccines are a promising strategy for preventing cancer progression through antitumor immunity activation. Some vaccines, such as Sipuleucel-T (an autologous active cellular immunotherapy), have been applied clinically.
Shengxian Li +4 more
doaj +1 more source
Going beyond the individual: How state-level characteristics relate to HPV vaccine rates in the United States [PDF]
, 2019 Background The human papillomavirus (HPV) vaccine is an underutilized cancer control practice in the United States. Although individual contextual factors are known to impact HPV vaccine coverage rates, the impact of macro-level elements are still ...
Brownson, Ross C +3 more
core +2 more sources
Expert Review of Vaccines, 2013 In 2010, the US FDA approved the first therapeutic cancer vaccine for the treatment of castration refractory prostate cancer - sipuleucel-T. Prostate cancer is an ideal model for cancer vaccine development based on the ready demonstration of humoral and cellular immunity to a range of cancer antigens as well as often slow progression which means that ...
Michael, Agnieszka +3 more
openaire +5 more sources
Cancer Vaccines: Adjuvant Potency, Importance of Age, Lifestyle, and Treatments
Frontiers in Immunology, 2021 Although the discovery and characterization of multiple tumor antigens have sparked the development of many antigen/derived cancer vaccines, many are poorly immunogenic and thus, lack clinical efficacy.
S. Cuzzubbo +5 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.The citric acid/urea (CA‐Urea) precursor system offers a versatile, scalable route to carbon dots with tunable luminescence and multifunctionality. Mechanistic insights into precursor chemistry and reaction parameters have enabled doping, surface modification, and hybridization strategies, yielding CDs for luminescent devices, sensing, catalysis ...
Yupeng Liu +10 more
wiley +1 more source
Potential association factors for developing effective peptide-based cancer vaccines
Frontiers in Immunology, 2022 Peptide-based cancer vaccines have been shown to boost immune systems to kill tumor cells in cancer patients. However, designing an effective T cell epitope peptide-based cancer vaccine still remains a challenge and is a major hurdle for the application ...
Chongming Jiang +14 more
doaj +1 more source
Improved induction of anti-melanoma T cells by adenovirus-5/3 fiber modification to target human DCs [PDF]
, 2018 To mount a strong anti-tumor immune response, non T cell inflamed (cold) tumors may require combination treatment encompassing vaccine strategies preceding checkpoint inhibition.
Chondronasiou, Dafni +9 more
core +3 more sources
Journal of British Surgery, 1998 Abstract Background Advances in molecular pathology have enabled a number of colorectal cancer antigens to be identified and characterized. The commonest investigated include 17-1A, 791Tgp72 and carcinoembryonic antigen.
C A, Maxwell-Armstrong +2 more
openaire +2 more sources
Synergistic potential of immune checkpoint inhibitors and therapeutic cancer vaccines.
Seminars in Cancer Biology, 2022 Cancer vaccines and immune checkpoint inhibitors (ICIs) function at different stages of the cancer immune cycle due to their distinct mechanisms of action. Therapeutic cancer vaccines enhance the activation and infiltration of cytotoxic immune cells into
Mariam Oladejo, Wyatt Paulishak, L. Wood
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett +19 more
wiley +1 more source