Results 111 to 120 of about 5,770,101 (353)

Human Papillomavirus Infection: Prevention, Barriers to Vaccination, and the Need for Education [PDF]

, 2016
While there is no known cure for HPV, prophylactic vaccination provides an effective method of primary prevention against HPV-related diseases. However, many females and males never receive the HPV vaccine as recommended.
Kessler, Theresa A
core   +2 more sources

Cancer Microenvironment and Cancer Vaccine [PDF]

Cancer Microenvironment, 2012
The cancer microenvironment is constituted of non-transformed host stromal cells such as endothelial cells, fibroblasts, various immune cells, and a complex extra-cellular matrix secreted by both the normal and neoplastic cells embedded in it. The importance of the microenvironment and its potential in cancer therapy is just being established.
Zhen-Yu, Ding, Xue-Lin, Zou, Yu-Quan, Wei   +2 more
openaire   +2 more sources

Fluid Forces Control Structural Remodeling of Blind‐Ended Lymphatic Microvessels

Advanced Healthcare Materials, EarlyView.
Using innovative microfluidic biofabrication with fluid mechanical insights, we recapitulated the blind‐ended microanatomy and physiological drainage properties of capillary lymphatics. Our results reveal the interrelationship between intra‐ and extraluminal regions of lymphatic vessels due to flow‐induced sprouting and morphological changes that ...
Jacob C. Holter, Shashwat S. Agarwal, Joseph W. Tinapple, Joseph M. Barlage, Travis H. Jones, Jonathan W. Song   +5 more
wiley   +1 more source

Protocol for identifying stressed granulocytes from septic mice

STAR Protocols
Summary: Sepsis trains stressed granulocytes to boost nonspecific response and trigger a new wave of inflammation when facing secondary infection. Here, we present a protocol for a murine model of sepsis with secondary infection.
Yu Hao, Can Zhang, Fangyuan Li, Yang Fan, Kexin Chi, Hui Zeng, Ju Zhang   +6 more
doaj   +1 more source

Role of HTLV-1 orf-I encoded proteins in viral transmission and persistence

Retrovirology, 2019
The human T cell leukemia virus type 1 (HTVL-1), first reported in 1980 by Robert Gallo’s group, is the etiologic agent of both cancer and inflammatory diseases.
Sarkis Sarkis, Veronica Galli, Ramona Moles, David Yurick, Georges Khoury, Damian F. J. Purcell, Genoveffa Franchini, Cynthia A. Pise-Masison   +7 more
doaj   +1 more source

Biological therapy in the treatment of melanoma [PDF]

, 2018
Melanoma is one of the most aggressive tumors and its incidence is on the rise. The low rates of survival in metastatic melanoma has led to the development of new drugs for this type of patient, such as biological therapy which has shown remarkable ...
Benea, Vasile, Georgescu, Simona Roxana, Ghita, Ela, Ioghen, Mihaela Roxana, Ion, Alexandra-Florentina, Mitran, Cristina-Iulia, Mitran, Madalina-Irina, Sarbu, Maria Isabela, Tampa, Mircea   +8 more
core   +3 more sources

Biomimetic Copper Nanoparticles Coated with ACE2‐Overexpressing Membranes for Selective SARS‐CoV‐2 Neutralization and Disinfection

Advanced Healthcare Materials, EarlyView.
By fusing ACE2‐overexpressing membrane‐integrated liposome (MIL) with copper nanoparticles, the biomimetic Cu@MIL nanostructures were created that directly hijack the SARS‐CoV‐2 entry pathway. These particles combine potent virus‐targeting precision with intrinsic antiviral activity, achieving rapid neutralization and disinfection.
Pooja Aich, Wei‐Pang Chung, Wen‐Jyun Wang, Hidenobu Takahashi, Ming‐Shun Hsieh, Ying‐Chen Lin, Oh Seok Kwon, Wei‐Peng Li, Wei‐Lun Huang   +8 more
wiley   +1 more source

Breastfeeding and Neonatal Age Influence Neutrophil-Driven Ontogeny of Blood Cell Populations in the First Week of Human Life

Journal of Immunology Research
The first few days of life are characterized by rapid external and internal changes that require substantial immune system adaptations. Despite growing evidence of the impact of this period on lifelong immune health, this period remains largely uncharted.
Sebastiano Montante, Rym Ben-Othman, Nelly Amenyogbe, Asimenia Angelidou, Anita van den Biggelaar, Bing Cai, Yixuan Chen, Alansana Darboe, Joann Diray-Arce, Rebecca Ford, Olubukola Idoko, Amy Lee, Mandy Lo, Kerry McEnaney, Mehrnoush Malek, David Martino, Geraldine Masiria, Oludare A. Odumade, William Pomat, Casey Shannon, Kinga Smolen, The EPIC Consortium, Al Ozonoff, Peter Richmond, Scott Tebbutt, Ofer Levy, Beate Kampmann, Ryan Brinkman, Tobias Kollmann   +28 more
doaj   +1 more source

Elevated NTCP expression by an iPSC-derived human hepatocyte maintenance medium enhances HBV infection in NTCP-reconstituted HepG2 cells

Cell & Bioscience, 2021
Background The sodium taurocholate cotransporting polypeptide (NTCP) is a functional receptor for hepatitis B virus (HBV). NTCP-reconstituted human hepatoma cells support HBV infection, but the infection is suboptimal and no apparent HBV spread has been ...
Xinlei Li, Zhaohui Xu, Bidisha Mitra, Minghang Wang, Haitao Guo, Zongdi Feng   +5 more
doaj   +1 more source

The role of the immune system in brain metastasis [PDF]

, 2019
Metastatic brain tumors are the most common brain tumors in adults. With numerous successful advancements in systemic treatment of most common cancer types, brain metastasis is becoming increasingly important in the overall prognosis of cancer patients ...
Dey, Mahua, Leibold, Adam T., Monaco, Gina N.   +2 more
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