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Philosophical Transactions of the Royal Society B: Biological Sciences, 2011 Abstract While vaccines are primarily thought of in terms of their use for prevention of infectious diseases, they can potentially be used to prevent or treat cancer. This manuscript explores the rationale for vaccines and immunotherapies for cancer from both the scientific and the global needs perspectives.
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Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects
Cell Reports, 2021 Summary: SARS-CoV-2 is one of three coronaviruses that have crossed the animal-to-human barrier and caused widespread disease in the past two decades. The development of a universal human coronavirus vaccine could prevent future pandemics.
Madeleine F. Jennewein +28 more
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Cancer Microenvironment and Cancer Vaccine [PDF]
Cancer Microenvironment, 2012 The cancer microenvironment is constituted of non-transformed host stromal cells such as endothelial cells, fibroblasts, various immune cells, and a complex extra-cellular matrix secreted by both the normal and neoplastic cells embedded in it. The importance of the microenvironment and its potential in cancer therapy is just being established.
Zhen-Yu, Ding +2 more
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Plant production and immunogenic characterisation of Human papillomavirus chimaeric vaccines [PDF]
, 2011 Includes abstract.Includes bibliographical references (leaves 153-175).Cervical cancer is primarily caused by infection with Human papillomavirus (HPV) and is a global concern, particularly in developing countries which contain ~80% of the cervical ...
Pineo, Catherine
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PathogensThe transient depletion of monocytes alone prior to exposure of macaques to HTLV-1 enhances both HTLV-1WT (wild type) and HTLV-1p12KO (Orf-1 knockout) infectivity, but seroconversion to either virus is not sustained over time, suggesting a progressive ...
Anna Gutowska +12 more
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OncoImmunology, 2017 Purpose: Although local oncolytic viral therapy (OVT) may enhance tumor lysis, antigen release, and adaptive immune responses, systemic antitumor responses post-therapy are limited. Adoptive immunotherapy with autologous dendritic cells (DC) and cytokine-
Jun Ren +13 more
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Advances in Neoantigen-Based Cancer Vaccines. [PDF]
Cancers (Basel)Neoantigen-based immunotherapies harness somatic mutations as tumor-specific targets and represent a major advance in personalized cancer treatment.
Wu AC, Nakamura Y, Kiyotani K.
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OncoImmunology, 2013 These are exciting times for the field of cancer immunotherapy. Although the clinical efficacy of monoclonal antibodies has been demonstrated since the early 1990s, the therapeutic profile of other immunotherapeutic approaches-especially vaccines-has not yet been formally clarified.
Yaddanapudi, Kavitha +2 more
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Therapeutic cancer vaccines: Where do we stand?
Journal of Integrative Medicine and Research, 2023 Vaccines and immunotherapy have transformed the treatment modalities and prevention of several diseases including malignancy. Vaccines for infectious diseases have been in use for many decades, but very few cancer vaccines are approved for human use ...
Rajlaxmi Sarangi +4 more
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