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Functional properties and sequence variation of HTLV-1 p13
Human T cell leukemia virus type-1 (HTLV-1) was the first retrovirus found to cause cancer in humans, but the mechanisms that drive the development of leukemia and other diseases associated with HTLV-1 infection remain to be fully understood. This review
Maria Omsland +9 more
doaj +1 more source
mRNA vaccine in cancer therapy: Current advance and future outlook
Messenger ribonucleic acid (mRNA) vaccines are a relatively new class of vaccines that have shown great promise in the immunotherapy of a wide variety of infectious diseases and cancer.
Youhuai Li +10 more
doaj +1 more source
Immunotherapy of lung cancer: An update [PDF]
In Germany lung cancer is the leading cause of cancer-associated death in men. Surgery, chemotherapy and radiation may enhance survival of patients suffering from lung cancer but the enhancement is typically transient and mostly absent with advanced ...
Hatz, R. A. +15 more
core +1 more source
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley +1 more source
High expression of Rex-orf-I and HBZ mRNAs and bronchiectasis in lung of HTLV-1A/C infected macaques
HTLV-1 type-A rarely causes lung disease in humans, whereas HTLV-1 type-C is more frequently associated with respiratory failure and premature death.
Sarkis Sarkis +21 more
doaj +1 more source
HTLV-1 p13 Protein Hijacks Macrophage Polarization and Promotes T-Cell Recruitment
The human T-cell leukemia type-1 (HTLV-1) retrovirus establishes chronic life-long infection in a fraction of infected individuals associated with severe pathological conditions. Although the mechanism driving disease development is not fully understood,
Ramona Moles +11 more
doaj +1 more source
Application of Nanotechnology in Therapeutic Cancer Vaccines
Cancer vaccines stimulate the immune system within the body by introducing tumor antigens in various forms, such as tumor cells, tumor‐related proteins or peptides, and genes expressing tumor antigens, into the body.
Jianmei Guo +6 more
doaj +1 more source
Current advances in cancer vaccines targeting NY-ESO-1 for solid cancer treatment
New York-esophageal cancer 1 (NY-ESO-1) belongs to the cancer testis antigen (CTA) family, and has been identified as one of the most immunogenic tumor-associated antigens (TAAs) among the family members.
Hong Zhou +13 more
doaj +1 more source
AbstractLearning ObjectivesAfter completing this course, the reader will be able to: Explain the relationship between the tumor and host immune system.Recognize the mechanisms by which tumor cells escape the immune surveillance.Recognize the potential of vaccines in the treatment and prevention of cancer.Access and take the CME test online and receive ...
openaire +2 more sources
Objective Ambulatory care–sensitive conditions (ACSCs) serve as indicators of access, quality, and performance of the health system. This study aimed to determine rheumatoid arthritis (RA)‐specific ACSCs for use in the evaluation of care system access and quality.
Kara Irwin +7 more
wiley +1 more source

