Results 221 to 230 of about 286,222 (357)

Engineering Anti-Tumor Immunity: An Immunological Framework for mRNA Cancer Vaccines. [PDF]

Vaccines (Basel)
Roy O, Anderson KS.
europepmc   +1 more source

Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination

Advanced Science, EarlyView.
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi, Colby J. Agostino, Jinwei Huang, Toshitha Kannan, Niklas Laenger, Jennifer Londregan, Katlyn Lederer, Michaela Helble, Nicole Bedanova, Cory Livingston, Ebony N. Gary, Madison McCanna, Marta Tarquis Medina, Rumi Habib, Ignacio Rodriguez Relaño, Ivan Maillard, Ami Patel, David Allman, Andrew Kossenkov, Amelia Escolano, Daniel W. Kulp, David. B. Weiner   +21 more
wiley   +1 more source

Personalized cancer vaccines: promise, challenges, and the path forward. [PDF]

Ann Med Surg (Lond)
Shafique M, Chaman Lal K, Ahmed MF.
europepmc   +1 more source

ON THE TREATMENT OF CANCER BY THERAPEUTIC INOCULATIONS OF A BACTERIAL VACCINE,

, 1906
C. W. Jacobs, Victor Geets
openalex   +2 more sources

Genome‐Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle‐Mediated siRNA Delivery

Advanced Science, EarlyView.
A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source

Editorial: Advancements in antibody-based immunotherapy and cancer vaccines for hepatocellular carcinoma. [PDF]

Front Immunol
Tabll AA, Saeed A, Elkafrawy MS, El-Kafrawy SA.   +3 more
europepmc   +1 more source

Characterization of tumor-infiltrating lymphocytes in ovarian cancer and development of a peptide-based anti-cancer vaccine

, 2017
Kevin Röhle
openalex   +1 more source

MARPLE: A Proximity‐Triggered CRISPR‐Cas13 Platform for Ultrasensitive Antibody Detection

Advanced Science, EarlyView.
MARPLE is a modular CRISPR‐Cas13 immunoassay that uses antibody‐induced proximity to trigger a toehold‐exchange reaction, releasing an RNA activator for Cas13. This one‐pot, isothermal architecture enables ultrasensitive (femtomolar) and highly specific detection of diverse antibodies, including therapeutic, pathogen‐specific, and cancer‐associated ...
Elena Spezzani, Luca Capelli, Denise Di Lena, Alejandro Chamorro‐Garcia, Rudy Ippodrino, Alessandro Porchetta, Alessandro Bertucci   +6 more
wiley   +1 more source

Minimalist mRNAs: A fast track to cancer vaccines. [PDF]

Mol Ther Nucleic Acids
Salaberry L, Covo-Vergara Á, Beloki U, Silva-Pilipich N, Smerdou C.   +4 more
europepmc   +1 more source

Biotinylated Streptavidin Surface Coating Improves the Efficacy of a PLGA Microparticle-Based Cancer Vaccine

, 2020
Brett Gross, Khanidtha Chitphet, Amaraporn Wongrakpanich, Emad I. Wafa, Lyse A. Norian, Aliasger K. Salem   +5 more
openalex   +2 more sources