Genetic variants of EcPV2 E6 and E7 in equine genital and oronasal squamous cell carcinoma
Equine Veterinary Journal, EarlyView.Abstract Background Since its discovery in 2008, equine papillomavirus type 2 (EcPV2) has been detected in up to 100% of equine genital and up to 40% of equine oronasal squamous cell carcinomas (SCCs). Preliminary sequence data point to the existence of EcPV2 E6 and E7 oncogene variants compared to the British reference sequence from 2008.
Maya Jenner, Sabine Brandt
wiley +1 more source
From Standard of Care to mRNA Cancer Vaccines and Spatial Architecture-Based Precision Therapy in PDAC: Challenges and Expectations. [PDF]
Cancers (Basel)Stea EX, Kydonakis N, Roukos DH.
europepmc +1 more source
Exploration, EarlyView.This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi +5 more
wiley +1 more source
Personalized Cancer Vaccines in the Clinical Trial Pipeline. [PDF]
Asia Pac J Clin OncolIamukova L, Alferova E.
europepmc +1 more source
Under‐Explored Species, Breeds and Cell Types With Potential for Cultivated Meat Production
Food Bioengineering, EarlyView.This graphical abstract illustrates how the strategic selection of overlooked cell lines from novel species and specific agricultural breeds can help overcome current manufacturing bottlenecks in cultivated meat production. The schematic links the concept of an ‘ideal cell line’ to four key bioprocessing and product advantages that can be optimised ...
William Gordon‐Petrovskii +6 more
wiley +1 more source
Personalized cancer vaccines: promise, challenges, and the path forward. [PDF]
Ann Med Surg (Lond)Shafique M, Chaman Lal K, Ahmed MF.
europepmc +1 more source
Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors
FlexMat, EarlyView.This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu +3 more
wiley +1 more source
mRNA Cancer Vaccines: From Pandemic Paradigm to Personalized Oncology Therapeutics. [PDF]
Cancer InnovYang B, Liu J, Li Y, Liu X.
europepmc +1 more source
Lung cancer vaccines to enhance immune checkpoint inhibitor therapy: evidence and future perspectives. [PDF]
J Hematol OncolTang Z, Zha L, Liang R, Li T.
europepmc +1 more source
Key Clinical Frontiers of mRNA Loaded Lipid Nanoparticles in Cancer Vaccines. [PDF]
Int J NanomedicineCao L +5 more
europepmc +1 more source