Results 311 to 320 of about 269,977 (355)

Recent progress in mRNA cancer vaccines. [PDF]

Hum Vaccin Immunother
Yao R, Xie C, Xia X.
europepmc   +1 more source

Hybrid Molecules as Efficient Drugs against Multidrug‐Resistant Malaria Parasites

ChemMedChem, EarlyView.
Among hybrid molecules currently developed as antimalarial drug candidates, emoquine‐1 exhibits high activity against all the multidrug‐resistant Plasmodium strains tested up to now, including artemisinin‐resistant quiescent parasites, critical parameters for promising antimalarial drugs. It is also curative in mouse malaria.
Anne Robert, Lucie Paloque, Jean‐Michel Augereau, Flore Nardella, Michel Nguyen, Bernard Meunier, Françoise Benoit‐Vical   +6 more
wiley   +1 more source

Development and Clinical Applications of Therapeutic Cancer Vaccines with Individualized and Shared Neoantigens. [PDF]

Vaccines (Basel)
Hao Q, Long Y, Yang Y, Deng Y, Ding Z, Yang L, Shu Y, Xu H.   +7 more
europepmc   +1 more source

Synopsis of the 5th annual Cancer Vaccines and Immunotherapy Colloquium at Walker's Cay

, 2003
Malcolm S. Mitchell, W. Martin Kast
openalex   +2 more sources

Intracellular and Extracellular Efficacy of Homoisoflavone Derivatives Against Mycobacterium tuberculosis: Progress Toward Novel Antitubercular Agents

ChemMedChem, Accepted Article.
Tuberculosis (TB) is the leading cause of death among infectious diseases, and new studies focusing new anti‐TB drugs are urgent due to the emergence of drug‐resistant strains. In this regard, homoisoflavones, an underexplored subgroup of flavonoids, were explored for their potential as anti‐TB agents.
Sanderson D. Calixto, Juliane S. Falcão, Stella S. Antunes, Marlon H. Araujo, Alexandre L. B. Cunha, David R. Martins, Sarah M. R. Nascimento, Thatiana L. B. V. Simão, Elena B. Lasunskaia, Nelilma C. Romeiro, Paulo R. R. Costa, Michelle Muzitano, Guilherme S. Caleffi   +12 more
wiley   +1 more source

Circular RNA as a source of neoantigens for cancer vaccines. [PDF]

J Immunother Cancer
Ren Y, Manoharan T, Liu B, Cheng CZM, En Siew B, Cheong WK, Lee KY, Tan IJ, Lieske B, Tan KK, Chia G.   +10 more
europepmc   +1 more source

Millisecond phase transition kinetics of lyotropic liquid crystalline nanoparticles observed by time‐resolved small angle x‐ray solution scattering

ChemPhysChem, Accepted Article.
This study investigates the dynamic behavior of lyotropic liquid crystal nanoparticles (LCNPs), which are widely recognized for their applications in drug delivery. By employing nanosecond near‐infrared (NIR) laser pulse‐induced temperature jump (T‐jump) and time‐resolved X‐ray solution scattering (TRXSS), the structural dynamics of phase transitions ...
Changmin Lee, Arnold M. Chan, Adam K. Nijhawan, Madeline B. Ho, Irina Kosheleva, Lin X. Chen   +5 more
wiley   +1 more source

Cancer vaccines: from an immunology perspective. [PDF]

Immunother Adv
Makker S, Galley C, Bennett CL.
europepmc   +1 more source

Advances in Isotope Labeling for Solution Nucleic Acid Nuclear Magnetic Resonance Spectroscopy

ChemPlusChem, EarlyView.
Recent advances in the field of nucleic acid nuclear magnetic resonance (NMR) are presented. Stable isotope labeling protocols and new approaches to segmentally label nucleic acid with NMR‐active residues are summarized. The novel methods will have a strong impact on the future of nucleic acid NMR and the characterization of structure and dynamics of ...
Stefan Hilber, Solomon Kojo Attionu, Theodore Kwaku Dayie, Christoph Kreutz   +3 more
wiley   +1 more source

Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics

Clinical Pharmacology &Therapeutics, EarlyView.
The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou, Rohit Rao, Monica E. Shapiro, Nessy Tania, Cody Herron, Cynthia J. Musante, Jim H. Hughes   +6 more
wiley   +1 more source