Results 311 to 320 of about 286,222 (357)
Some of the next articles are maybe not open access.
Hematology/Oncology Clinics of North America, 2001
Attempts to generate an anticancer immune response in vivo in patients with cancer have taken several forms. Although to date there have been relatively few published studies describing the effects of the approach in hematologic malignancy, that circumstance is expected to change rapidly during the next few years. In solid tumors, it is not known which,
R F, Rousseau +3 more
+7 more sources
Attempts to generate an anticancer immune response in vivo in patients with cancer have taken several forms. Although to date there have been relatively few published studies describing the effects of the approach in hematologic malignancy, that circumstance is expected to change rapidly during the next few years. In solid tumors, it is not known which,
R F, Rousseau +3 more
+7 more sources
Seminars in Oncology Nursing, 2003
To provide a review of cancer vaccines, how they work, and the current state of the science underlying these treatments.Research studies, review articles, book chapters, personal communications.Vaccines have been studied in a variety of malignancies; however, melanoma has provided the best tumor model for vaccination.
Paula M, Muehlbauer +1 more
+6 more sources
To provide a review of cancer vaccines, how they work, and the current state of the science underlying these treatments.Research studies, review articles, book chapters, personal communications.Vaccines have been studied in a variety of malignancies; however, melanoma has provided the best tumor model for vaccination.
Paula M, Muehlbauer +1 more
+6 more sources
Nature Reviews Cancer, 2021
Therapeutic cancer vaccines have undergone a resurgence in the past decade. A better understanding of the breadth of tumour-associated antigens, the native immune response and development of novel technologies for antigen delivery has facilitated improved vaccine design.
Saxena, M. +3 more
openaire +3 more sources
Therapeutic cancer vaccines have undergone a resurgence in the past decade. A better understanding of the breadth of tumour-associated antigens, the native immune response and development of novel technologies for antigen delivery has facilitated improved vaccine design.
Saxena, M. +3 more
openaire +3 more sources
Current Protocols in Human Genetics, 1997
AbstractThis unit describes the use of retroviral vectors that can be successfully employed for gene transfer into both primary tumor cultures and established cell lines. The unit includes procedures for assaying the stability of the vaccine following gene transfer.
T F, Greten, E M, Jaffee
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AbstractThis unit describes the use of retroviral vectors that can be successfully employed for gene transfer into both primary tumor cultures and established cell lines. The unit includes procedures for assaying the stability of the vaccine following gene transfer.
T F, Greten, E M, Jaffee
openaire +5 more sources
Hematology/Oncology Clinics of North America, 2019
Cancer vaccines are a promising strategic approach within the rapidly growing field of immuno-oncology. Therapeutic cancer vaccines are distinct from prophylactic vaccines and vary by both target antigen and vaccine platform. There are currently 3 FDA-approved therapeutic cancer vaccines: intravesical BCG live, sipuleucel-T, and T-VEC.
Peter J, DeMaria, Marijo, Bilusic
openaire +2 more sources
Cancer vaccines are a promising strategic approach within the rapidly growing field of immuno-oncology. Therapeutic cancer vaccines are distinct from prophylactic vaccines and vary by both target antigen and vaccine platform. There are currently 3 FDA-approved therapeutic cancer vaccines: intravesical BCG live, sipuleucel-T, and T-VEC.
Peter J, DeMaria, Marijo, Bilusic
openaire +2 more sources
Current Gene Therapy, 2007
Cytotoxic chemotherapy is associated with modest survival advantage as initial treatment of advanced lung cancer. However, toxicity and minimal benefit to use second line treatment justifies exploration of alternative approaches. Recent understanding of mechanisms by which tumor antigen recognition can be enhanced has justified development of a recent ...
Rob, Eager +2 more
openaire +2 more sources
Cytotoxic chemotherapy is associated with modest survival advantage as initial treatment of advanced lung cancer. However, toxicity and minimal benefit to use second line treatment justifies exploration of alternative approaches. Recent understanding of mechanisms by which tumor antigen recognition can be enhanced has justified development of a recent ...
Rob, Eager +2 more
openaire +2 more sources
2012 Sixth International Conference on Complex, Intelligent, and Software Intensive Systems, 2012
Cancer vaccine research is a hot topic for medical treatments of cancer. Identification of candidate antigenic stimuli for the vaccine is already improved using immune-informatics. Subsequent test in vivo are expensive and time consuming. There is an increasing request to a modeling approach to speed up this phase of vaccine research.
PAPPALARDO, FRANCESCO, MOTTA, Santo
openaire +2 more sources
Cancer vaccine research is a hot topic for medical treatments of cancer. Identification of candidate antigenic stimuli for the vaccine is already improved using immune-informatics. Subsequent test in vivo are expensive and time consuming. There is an increasing request to a modeling approach to speed up this phase of vaccine research.
PAPPALARDO, FRANCESCO, MOTTA, Santo
openaire +2 more sources
Expert Opinion on Therapeutic Targets, 2004
Cancer vaccines - a dream or a reality? There is no doubt that a time will come when this new approach to cancer treatment will provide opportunities that will be both complementary and synergistic with existing treatments. Novelty is often linked to risk, and if there is a given medical field that desperately needs therapeutic improvement, cancer is ...
openaire +2 more sources
Cancer vaccines - a dream or a reality? There is no doubt that a time will come when this new approach to cancer treatment will provide opportunities that will be both complementary and synergistic with existing treatments. Novelty is often linked to risk, and if there is a given medical field that desperately needs therapeutic improvement, cancer is ...
openaire +2 more sources
Surgical Oncology Clinics of North America, 2007
Therapeutic cancer vaccines target the cellular arm of the immune system to initiate a cytotoxic T-lymphocyte response against tumor-associated antigens. Immunotherapy offers one of the few therapeutic options that reproducibly leads to a subset of patients with long-term remissions (seemingly cures) of widely metastatic disease.
Lilah F, Morris, Antoni, Ribas
openaire +2 more sources
Therapeutic cancer vaccines target the cellular arm of the immune system to initiate a cytotoxic T-lymphocyte response against tumor-associated antigens. Immunotherapy offers one of the few therapeutic options that reproducibly leads to a subset of patients with long-term remissions (seemingly cures) of widely metastatic disease.
Lilah F, Morris, Antoni, Ribas
openaire +2 more sources