Results 71 to 80 of about 269,977 (355)
Using MRI Cell Tracking to Monitor Immune Cell Recruitment in Response to a Peptide-Based Cancer Vaccine [PDF]
, 2017 Purpose: MRI cell tracking can be used to monitor immune cells involved in the immunotherapy response, providing insight into the mechanism of action, temporal progression of tumour growth and individual potency of therapies. To evaluate whether MRI could be used to track immune cell populations in response to immunotherapy, CD8+ cytotoxic T cells ...
arxiv +1 more source
Improvement of antitumor therapies based on vaccines and immune-checkpoint inhibitors by counteracting tumor-immunostimulationw [PDF]
, 2018 Immune-checkpoint inhibitors and antitumor vaccines may produce both tumor-inhibitory and tumor-stimulatory effects on growing tumors depending on the stage of tumor growth at which treatment is initiated.
Bustuoabad, Oscar David +8 more
core +2 more sources
Expression of HIV from a 1-LTR circular DNA in the absence of integration
RetrovirologyBackground Like all retroviruses, two kinds of viral DNA are present in the nucleus of HIV-infected cells: integrated DNA and a pool of unintegrated DNA containing linear and circular forms. For the most part, it has been difficult to examine the role of
Corrado Gurgo +4 more
doaj +1 more source
Aging and Cancer Vaccines [PDF]
Critical Reviews in Oncogenesis, 2013 Cancer vaccination is less effective at old than at young age, due to T cell unresponsiveness. This is caused by age-related changes of the immune system. Major immune defects at older age are lack of naive T cells, impaired activation pathways of T cells and antigen-presenting cells (APC), and age-related changes in the tumor microenvironment (TME ...
Dinesh Chandra, Claudia Gravekamp
openaire +3 more sources
, 2009 Cancer vaccines are medicines that work by stimulating or restoring the immune system’s ability to fight cancers and disease. There are two types of cancer vaccines,prophylactic cancer vaccines, which are intended to prevent cancer from developing ...
Radji, M. (Maksum)
core
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
EBioMedicine, 2021 Background: Recent studies have provided evidence of T cell reactivity to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in significant numbers of non-infected individuals, which has been attributed to cross-reactive CD4 memory T cells from
Isaac Quiros-Fernandez +3 more
doaj
Recent Advances in Cancer Vaccines: Challenges, Achievements, and Futuristic Prospects
Vaccines, 2022 Cancer is a chronic disease, and it can be lethal due to limited therapeutic options. The conventional treatment options for cancer have numerous challenges, such as a low blood circulation time as well as poor solubility of anticancer drugs. Therapeutic
Madhu Gupta +13 more
doaj +1 more source
The Oncologist, 2002 AbstractLearning ObjectivesAfter completing this course, the reader will be able to: Explain the relationship between the tumor and host immune system.Recognize the mechanisms by which tumor cells escape the immune surveillance.Recognize the potential of vaccines in the treatment and prevention of cancer.Access and take the CME test online and receive ...
openaire +2 more sources
Characterization of Murine Breast Cancer Cell Lines for Anti-Cancer Vaccine [PDF]
, 2017 Breast cancer is the most commonly diagnosed cancer in women and the second leading cause of cancer death among women in the United States (1). While treatments involving radiation and chemotherapy currently exist, disease must be detected early in order
Frazier, Haven N
core +2 more sources