Results 71 to 80 of about 274,583 (262)
Frontiers in Pharmacology, 2021 Cancer vaccines represent among the most promising strategies in the battle against cancers. However, the clinical efficacy of current cancer vaccines is largely limited by the lack of optimized delivery systems to generate strong and persistent ...
Lu Han +6 more
doaj +1 more source
Understanding Barriers to HPV vaccine uptake in Appalachia [PDF]
, 2020 Every year in seven small counties of Ohio seventy-six people lose their lives to a completely preventable Human Papillomavirus-related cancer. These counties are not random, nor are they an anomaly.
Murphy, Michaela
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Journal of British Surgery, 1998 Abstract Background Advances in molecular pathology have enabled a number of colorectal cancer antigens to be identified and characterized. The commonest investigated include 17-1A, 791Tgp72 and carcinoembryonic antigen.
C A, Maxwell-Armstrong +2 more
openaire +2 more sources
Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers
Advanced Functional Materials, EarlyView.A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley +1 more source
Engaging the Immune Response to Normalize the Tumor Microenvironment [PDF]
, 2013 Solid tumors exist as heterogeneous populations comprised not only of malignant cells, but various other cell types, including cells that make up the vasculature, that can strongly influence tumorgenicity.
Sabins, Nina, Storkus, Walter
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Cancer Microenvironment and Cancer Vaccine [PDF]
Cancer Microenvironment, 2012 The cancer microenvironment is constituted of non-transformed host stromal cells such as endothelial cells, fibroblasts, various immune cells, and a complex extra-cellular matrix secreted by both the normal and neoplastic cells embedded in it. The importance of the microenvironment and its potential in cancer therapy is just being established.
Zhen-Yu, Ding +2 more
openaire +2 more sources
Advanced Functional Materials, EarlyView.The citric acid/urea (CA‐Urea) precursor system offers a versatile, scalable route to carbon dots with tunable luminescence and multifunctionality. Mechanistic insights into precursor chemistry and reaction parameters have enabled doping, surface modification, and hybridization strategies, yielding CDs for luminescent devices, sensing, catalysis ...
Yupeng Liu +10 more
wiley +1 more source
Protocol for identifying stressed granulocytes from septic mice
STAR ProtocolsSummary: Sepsis trains stressed granulocytes to boost nonspecific response and trigger a new wave of inflammation when facing secondary infection. Here, we present a protocol for a murine model of sepsis with secondary infection.
Yu Hao +6 more
doaj +1 more source
Role of HTLV-1 orf-I encoded proteins in viral transmission and persistence
Retrovirology, 2019 The human T cell leukemia virus type 1 (HTVL-1), first reported in 1980 by Robert Gallo’s group, is the etiologic agent of both cancer and inflammatory diseases.
Sarkis Sarkis +7 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Membrane vesicles derived from the probiotic Lacticaseibacillus casei BL23 demonstrate antimicrobial properties against Escherichia coli and a potential biological effect in improving the overall survival of C. elegans infected with Pseudomonas aeruginosa. These vesicles stimulated immune responses in primary cells without causing toxicity. Our results
Cecilia L. D'Antoni +11 more
wiley +1 more source