Results 71 to 80 of about 88,514 (261)
MARPLE: A Proximity‐Triggered CRISPR‐Cas13 Platform for Ultrasensitive Antibody Detection
Advanced Science, EarlyView.MARPLE is a modular CRISPR‐Cas13 immunoassay that uses antibody‐induced proximity to trigger a toehold‐exchange reaction, releasing an RNA activator for Cas13. This one‐pot, isothermal architecture enables ultrasensitive (femtomolar) and highly specific detection of diverse antibodies, including therapeutic, pathogen‐specific, and cancer‐associated ...
Elena Spezzani +6 more
wiley +1 more source
Frontiers in Bioengineering and Biotechnology, 2015 The present work defines a modified critical size rabbit ulna defect model for bone regeneration in which a non-resorbable barrier membrane was used to separate the radius from the ulna to create a valid model for evaluation of tissue-engineered ...
Rania M El Backly +11 more
doaj +1 more source
Aplicação da sequenciação de nova geração ao diagnóstico genético do cancro da mama hereditário [PDF]
, 2015 Introdução: O cancro da mama hereditário (CMH) constitui 5-10% dos casos de cancro da mama, dos quais cerca de 30% se devem a mutações germinais de elevada penetrância nos genes BRCA1 e BRCA2.
Gonçalves, João +6 more
core
Qualidade de vida dos doentes com cancro colorretal
Pensar Enfermagem, 2018 Introdução: O Cancro (CCR) é definido como um tumor maligno que acomete o cólon e o reto, e é mais comum em idades avançadas. Trata-se de uma das neoplasias mais frequentes na população adulta mundial, apresentando incidência e mortalidade crescentes em ...
Ramona Garcia Souza Dominguez +2 more
semanticscholar +1 more source
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.Quantitative phase maps of single cells recorded in flow cytometry modality feed a hierarchical architecture of machine learning models for the label‐free identification of subtypes of ovarian cancer. The employment of a priori clinical information improves the classification performance, thus emulating the clinical application of liquid biopsy during ...
Daniele Pirone +11 more
wiley +1 more source
Journal of Orthopaedics and Traumatology, 2017 Background The purpose of this study was to summarize the available evidence about total lumbar disc replacement (TDR), focusing our attention on four main topics: clinical and functional outcomes, comparison with fusion surgery results, rate of ...
Matteo Formica +6 more
doaj +1 more source
Arthritis &Rheumatology, Accepted Article.Objective Systemic lupus erythematosus (SLE) is characterized by increased type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama +16 more
wiley +1 more source
The Cowl - v.29 - n.2 - Jan 28, 1976 [PDF]
, 1976 The Cowl - student newspaper of Providence College. Volume 29, Number 2 - January 28, 1976. 8 pages. Note: The volume number printed on the banner page of this issue (XXIX) duplicates the volume number for the 1966-67 academic ...
core +1 more source
International Journal of Cancer, EarlyView.What's New? Immune checkpoint inhibitors (ICIs) improve survival in advanced gastroesophageal cancer (GEC), but their benefits may differ by sex. Little is known, however about the impact of sex‐related immune differences on ICI efficacy. In this meta‐analysis, sex‐specific outcomes of ICI therapy were evaluated in advanced GEC, encompassing both ...
Michael Masetti +4 more
wiley +1 more source
Gazeta Médica, 2018 INTRODUÇÃO: O rastreio do cancro da mama é realizado através da mamografia nas mulheres. O objetivo desta revisão foi avaliar se a mamografia de rastreio diminui a mortalidade por cancro da mama.
S. Alves, Bernardo Pereira, I. Peixoto
semanticscholar +1 more source