Results 81 to 90 of about 224,806 (322)

Genome Comparisons of Candida glabrata Serial Clinical Isolates Reveal Patterns of Genetic Variation in Infecting Clonal Populations

open access: yesFrontiers in Microbiology, 2019
Candida glabrata is an opportunistic fungal pathogen that currently ranks as the second most common cause of candidiasis. Although the mechanisms underlying virulence and drug resistance in C.
Laia Carreté   +6 more
semanticscholar   +1 more source

Host Transcriptomics and Culture‐Independent Testing for the Management of Febrile Neutropenia: Data From an Observational Study Conducted in a Bone Marrow Transplant Unit

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Background Managing febrile neutropenia is challenging due to the limited sensitivity of blood culture (BC) and the lack of tools differentiating infectious from non‐infectious fever. T2 magnetic resonance (T2MR) is a culture‐independent system detecting bacteria (T2Bacteria) and yeasts (T2Candida); SeptiCyte RAPID is a host response assay ...
Anna Maria Peri   +6 more
wiley   +1 more source

Eosinophilic cystitis caused by Candida glabrata: A case report

open access: yesUrology Case Reports, 2019
Eosinophilic cystitis is a rare disease of the bladder, for which there is no clear cause or standard treatment. We report the case of a 61 year old man who presented with irritative voiding symptoms and gross hematuria.
David T. Duong, Harris S. Goodman
doaj   +1 more source

An evolutionary perspective on zinc uptake by human fungal pathogens [PDF]

open access: yes, 2015
DW is supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (Grant Number 102549/Z/13/Z).Peer reviewedPublisher ...
Wilson, Duncan
core   +1 more source

In Vitro Activity of Ibrexafungerp, a Novel Glucan Synthase Inhibitor against Candida glabrata Isolates with FKS Mutations

open access: yesAntimicrobial Agents and Chemotherapy, 2019
Ibrexafungerp is a first-in-class glucan synthase inhibitor. In vitro activity was determined for 89 Candida glabrata isolates with molecularly identified FKS1 or FKS2 mutations conferring resistance to the echinocandins.
N. Nunnally   +4 more
semanticscholar   +1 more source

The structural, functional, and therapeutic potential of metacaspases in fungi and protozoa

open access: yesThe FEBS Journal, EarlyView.
Metacaspases are Ca2+‐dependent cysteine proteases whose structural characteristics, particularly calcium binding and autocatalytic processing, govern their activation and biological functions. These enzymes differ among microorganisms and regulate their cell cycles, making them excellent targets for drug development.
Ane C. M. Duarte   +9 more
wiley   +1 more source

Candida albicans biofilm heterogeneity does not influence denture stomatitis but strongly influences denture cleansing capacity [PDF]

open access: yes, 2017
Approximately 20  % of the UK population wear some form of denture prosthesis, resulting in denture stomatitis in half of these individuals. Candida albicans is primarily attributed as the causative agent, due to its biofilm -forming ability.
Allen   +18 more
core   +2 more sources

Microevolution of the pathogenic yeasts Candida albicans and Candida glabrata during antifungal therapy and host infection

open access: yesMicrobial Cell, 2019
Infections by the pathogenic yeasts Candida albicans and Candida glabrata are among the most common fungal diseases. The success of these species as human pathogens is contingent on their ability to resist antifungal therapy and thrive within the human ...
Pedro Pais   +5 more
semanticscholar   +1 more source

Salivary and Serum Cytokine Concentrations in Kidney Transplantation: A Prospective Study

open access: yesOral Diseases, EarlyView.
ABSTRACT Background Kidney transplant recipients (KTRs) experience immune modulation, which may lead to graft rejection and other adverse outcomes. Although serum cytokines are well‐established systemic immune markers, the role of salivary biomarkers has never been reported in the literature.
Luciano Miziara   +10 more
wiley   +1 more source

Candida glabrata spondylodiscitis: A case report

open access: yesThe Journal of Infection in Developing Countries, 2018
Introduction: Spondylodiscitis is an infection in the intervertebral disc space and adjacent end plates. It can be attributed to bacteria, mycobacteria or fungi. As the number of immunosuppressed patients continues to grow, the incidence of developing fungal infections has become more frequent. Methodology: We report the case of a 53-year-old ...
Christina El Khoury   +4 more
openaire   +4 more sources

Home - About - Disclaimer - Privacy