Results 141 to 150 of about 4,316,987 (297)
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley +1 more source
Candida Urinary Tract Infections; Treatment Protocol
Journal of Mazandaran University of Medical Sciences, 2017 Background and purpose: The choice of antifungal agent in treatment of Candida urinary tract infections (CUTI) is dependent on the site of infection, the underlying disease of the patient, and the pharmacokinetics/pharmacodynamics (PK/PD) of the agent ...
Mohammad Sadegh Rezai +5 more
doaj
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Vaginal azoles versus oral fluconazole in treatment of recurrent vulvovaginal candidiasis [PDF]
Background: Vulvovaginal candidiasis (VVC) is a fungal infection of the vagina and vulva. It is usually caused by Candida albicans, however, occasionally other candida species are responsible. The optimal treatment of VVC has not yet been defined.
فردی آذر, زهرا +3 more
core
MOLECULAR MECHANISMS OF DRUG RESISTANCE IN CANDIDA ALBICANS: ROLE OF TRANSCRIPTION FACTORS MCM1 AND ADA2 [PDF]
, 2011 Candida albicans is an opportunistic fungal pathogen responsible for localized as well as disseminated infections. C. albicans is the most commonly isolated specie from blood cultures, accounting for over 60% of all Candida isolates. The fungistatic drug
MOGAVERO, SELENE
core
Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics
Mass Spectrometry Reviews, EarlyView.ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers +5 more
wiley +1 more source
Medicine Bulletin, EarlyView.The figure was created in BioRender.com. ABSTRACT Accurate and early diagnosis remains a key challenge in modern disease management. Conventional diagnostic methods often suffer from limitations in sensitivity, spatial resolution, and practical usability.
Zizhuo Du +10 more
wiley +1 more source
Nordic Journal of Botany, EarlyView.Serra da Jiboia, located in the south‐central region of Bahia, represents an important ecotone between the Atlantic Forest and the Caatinga and harbors high floristic diversity and numerous endemic species. The Bromeliaceae family, well represented in the region, stands out for its ecological importance and adaptability to various microenvironments ...
Everton Hilo de Souza +5 more
wiley +1 more source
Clonagem, expressão heteróloga e obtenção de mutantes da trealase ácida de Candida glabrata [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Programa de Pós-Graduação em Biotecnologia, Florianópolis, 2010Candida glabrata é considerado um importante patógeno fúngico emergente devido principalmente ao incremento de pacientes ...
Lopes, Rafael Garcia
core
Aspartic Protease Inhibition Induces Proteomic Remodeling in Paracoccidioides brasiliensis
PROTEOMICS, EarlyView.ABSTRACT Paracoccidioidomycosis (PCM) is a major systemic mycosis in Latin America caused by Paracoccidioides brasiliensis, yet the contribution of aspartic proteases to fungal physiology and pathogenicity remains poorly understood. Here, we employed data‐independent acquisition (DIA)‐based quantitative proteomics to investigate the impact of pepstatin
Sarah Fernandes Lima +6 more
wiley +1 more source