Results 201 to 210 of about 1,393,284 (302)

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla García‐Iglesias, Jagoda Litowczenko, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

QTL/Segment Mapping and Candidate Gene Analysis for Oil Content Using a Wild Soybean Chromosome Segment Substitution Line Population. [PDF]

Plants (Basel)
Liu C, Ren J, Wen H, Zhen C, Han W, Chen X, He J, Liu F, Sun L, Xing G, Zhao J, Gai J, Wang W.   +12 more
europepmc   +1 more source

Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model

Advanced Healthcare Materials, EarlyView.
This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti, Cristina Richichi, Daniela Osti, Elena Ceccacci, Giovanni Bertalot, Camilla Cerutti, Giuseppina Giardina, Adriana Marinaro, Brunella Costanza, Valentina Gambino, Elena Zaccheroni, Daniela Tosoni, Maria G. Filippone, Marcello Del Corvo, Yinxiu Zhan, Teresa Gravina, Davide Corà, Monica Patanè, Bianca Pollo, Maria Giovanna Jodice, Salvatore Pece, Babette B. Weksler, Ignacio A. Romero, Pierre‐Olivier Couraud, Elisabetta Munzone, Massimiliano Del Bene, Francesco DiMeco, Giuliana Pelicci   +27 more
wiley   +1 more source

Research note: Pool sequencing nominates MITF as a key candidate gene for white-belted feathers in chickens. [PDF]

Poult Sci
Huang X, Jiang Y, Zheng N, Liu H, Weng Z, Wen J, Li J, Ma C.   +7 more
europepmc   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Rice drought tolerance QTLs: Meta-analysis improves resolution to a few candidate gene level [PDF]

, 2009
Ahmadi, Nourollah, Courtois, Brigitte, Frouin, Julien, Hamelin, Chantal, Khowaja, Farhkanda S., Price, Adam H., Rami, Jean-François, Ruiz, Manuel   +7 more
core  

Genome-Wide Association Analysis and Candidate Gene Identification for Resistance to "Milky Disease" in the Chinese Mitten Crab (<i>Eriocheir sinensis</i>). [PDF]

Biology (Basel)
Yu Y, Liang X, Sun N, Zheng Y, Li B, Hu Q, Zhao Y, Bai Y, Li X.   +8 more
europepmc   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

A Candidate Gene for Cerebro-Oculo-Nasal Syndrome: A Zinc-Finger Gene <i>ZNF185</i> Located at Xq28. [PDF]

Mol Syndromol
Hazan F, Yılmaz Uzman C, Emecen DA, Yılmazer MM, Öztürk T, Bilen MM, Hüvez A, İlhan R, Genel F, Ballar P.   +9 more
europepmc   +1 more source