Results 201 to 210 of about 755,351 (269)

Research note: Pool sequencing nominates MITF as a key candidate gene for white-belted feathers in chickens. [PDF]

Poult Sci
Huang X, Jiang Y, Zheng N, Liu H, Weng Z, Wen J, Li J, Ma C.   +7 more
europepmc   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

QTL/Segment Mapping and Candidate Gene Analysis for Oil Content Using a Wild Soybean Chromosome Segment Substitution Line Population. [PDF]

Plants (Basel)
Liu C, Ren J, Wen H, Zhen C, Han W, Chen X, He J, Liu F, Sun L, Xing G, Zhao J, Gai J, Wang W.   +12 more
europepmc   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

TOR1AIP2 as a candidate gene for dystonia-hemichorea/hemiballism. [PDF]

Parkinsonism Relat Disord
Kafantari E, Hernandez VJ, Necpál J, Leonidou M, Baureder R, Hedberg-Oldfors C, Jech R, Zech M, Schwartz TU, Puschmann A.   +9 more
europepmc   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

Genome-Wide Association Analysis and Candidate Gene Identification for Resistance to "Milky Disease" in the Chinese Mitten Crab (<i>Eriocheir sinensis</i>). [PDF]

Biology (Basel)
Yu Y, Liang X, Sun N, Zheng Y, Li B, Hu Q, Zhao Y, Bai Y, Li X.   +8 more
europepmc   +1 more source

A Candidate Gene for Cerebro-Oculo-Nasal Syndrome: A Zinc-Finger Gene <i>ZNF185</i> Located at Xq28. [PDF]

Mol Syndromol
Hazan F, Yılmaz Uzman C, Emecen DA, Yılmazer MM, Öztürk T, Bilen MM, Hüvez A, İlhan R, Genel F, Ballar P.   +9 more
europepmc   +1 more source

A near-complete genome assembly of cucumber line 6457 and identification of candidate gene controlling pedicel length. [PDF]

Hortic Res
Xie Y, Zhang C, Zhang J, Zhao J, Song X, Lei X, Fan L, Li X, Jia J, Wang C, Zhang X, Yan L, Song X.   +12 more
europepmc   +1 more source

Fine Mapping and Candidate Gene Identification of ORUFILM03g000096 Gene in Weedy Rice LM8: Insights into Grain Length Regulation. [PDF]

Rice (N Y)
Li F, Han Z, Zhou L, Fan W, Lou D, Ge J, Wang Y, Liu Z, Guo W, Qiao W, Cheng Y, Zhang L, Li D, Nong B, Dun B, Zheng X, Yang Q.   +16 more
europepmc   +1 more source