Results 211 to 220 of about 1,393,284 (302)

Delivery of candidate genes

Delivery of candidate ...
openaire   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

A near-complete genome assembly of cucumber line 6457 and identification of candidate gene controlling pedicel length. [PDF]

Hortic Res
Xie Y, Zhang C, Zhang J, Zhao J, Song X, Lei X, Fan L, Li X, Jia J, Wang C, Zhang X, Yan L, Song X.   +12 more
europepmc   +1 more source

Shellac‐Mediated Assembly of Nanoparticles for mRNA Delivery

Advanced Healthcare Materials, EarlyView.
A shellac‐mediated nanoparticle assembly strategy is presented, involving the complexation of mRNA and low‐molecular‐weight cationic molecules (e.g., polyethyleneimine, chitosan, lipids, and poly‐l‐lysine), followed by capping with shellac. This nanoparticle platform enables mRNA transfection following intravenous injection and facilitates gene editing
Meizhang Lu, Jingqu Chen, Zhixing Lin, Wanjun Xu, Tianzheng Wang, Shiyao Li, Die Yang, Frank Caruso   +7 more
wiley   +1 more source

Fine Mapping and Candidate Gene Identification of ORUFILM03g000096 Gene in Weedy Rice LM8: Insights into Grain Length Regulation. [PDF]

Rice (N Y)
Li F, Han Z, Zhou L, Fan W, Lou D, Ge J, Wang Y, Liu Z, Guo W, Qiao W, Cheng Y, Zhang L, Li D, Nong B, Dun B, Zheng X, Yang Q.   +16 more
europepmc   +1 more source

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

TOR1AIP2 as a candidate gene for dystonia-hemichorea/hemiballism. [PDF]

Parkinsonism Relat Disord
Kafantari E, Hernandez VJ, Necpál J, Leonidou M, Baureder R, Hedberg-Oldfors C, Jech R, Zech M, Schwartz TU, Puschmann A.   +9 more
europepmc   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Genetic Evolution of Melanoma: Comparative Analysis of Candidate Gene Mutations in Healthy Skin, Nevi, and Tumors from the Same Patients. [PDF]

Int J Mol Sci
Gil-Barrachina M, Hernando B, Perez-Pastor G, Alegre-de-Miquel V, Valenzuela-Oñate C, Minguez-Lujan S, Monfort-Lanzas P, Tomas-Bort E, Marques-Torrejon MA, Martinez-Cadenas C.   +9 more
europepmc   +1 more source

IX. Candidate Genes [PDF]

Molecular Psychiatry, 1999
openaire   +1 more source