Results 71 to 80 of about 1,155,248 (307)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Polymorphisms in MyoD1, MyoG, MyF5, MyF6, and MSTN genes in Santa Inês sheep [PDF]
Pesquisa Agropecuária Brasileira, 2019 : The objective of this work was to sequence the MyoD1, MyoG, MyF5, MyF6, and MSTN genes and to identify polymorphisms in Santa Inês sheep (Ovis aries).
Luis Paulo Batista Sousa Junior +7 more
doaj +1 more source
PSYCHOPHARMACOLOGIC TARGETS IN PERSONALIZED PSYCHIATRY
Journal of Experimental and Molecular Biology, 2022 The advances made on genetic influence on response and side effects of psychiatric pharmacotherapy improved the concept of personalized psychiatry. The current evidence suggests that testing can be useful in patients who did not respond or tolerate at ...
Neamtu Monica
doaj +1 more source
Permanent Draft Genome Sequence of Photorhabdus temperata Strain Hm, an Entomopathogenic Bacterium Isolated from Nematodes [PDF]
, 2017 Photorhabdus temperata strain Hm is an entomopathogenic bacterium that forms a symbiotic association with Heterorhabditis nematodes. Here, we report a 5.0-Mbp draft genome sequence for P.
Abebe-Akele, Feseha +7 more
core +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Candidate genes of Waldenström’s macroglobulinemia: current evidence and research
The Application of Clinical Genetics, 2013 Giada Bianchi,1 Antonio Sacco,1 Shaji Kumar,2 Giuseppe Rossi,3 Irene Ghobrial,1 Aldo Roccaro11Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 2Division of Hematology, Mayo Clinic, Rochester, MN, USA ...
Bianchi G +5 more
doaj
Frontiers in Plant Science, 2023 To investigate the genetic mechanisms underlying the reproductive traits (time to flowering and maturity) in wheat and identify candidate genes associated, a phenotypic analysis was conducted on 239 wheat accessions (lines) from around the world.
Yindeng Ding +9 more
doaj +1 more source
Allelic diversity at orthologous candidate genes for drought tolerance in cereal crops: Example of the ASR gene family [PDF]
, 2008 Drought is a major abiotic stress. Many candidate genes have been proposed during the last years to explain aspects of tolerance to drought stress, for a specific crop and in a specific environment.
Baum, Michaël +8 more
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Variability of some genes of the somatotropic axis in the Piemontese cattle breed
Italian Journal of Animal Science, 2011 Growth hormone (GH) is a major participant in the control of several complex physiological processes, including growth and metabolism. The growth promoting aspects are generally mediated by the insulin-like growth factor 1 (IGF-1), produced primarily in ...
S. Sartore, L. Di Stasio
doaj +1 more source